Követés
Douglas Easton
Douglas Easton
Professor of Genetic Epidemiology, University of Cambridge
E-mail megerősítve itt: medschl.cam.ac.uk
Cím
Hivatkozott rá
Hivatkozott rá
Év
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
1958 Birth Cohort Controls Jones Richard W. 18 McArdle Wendy L. 18 Ring ...
Nature 447 (7145), 661-678, 2007
95012007
Identification of the breast cancer susceptibility gene BRCA2
R Wooster, G Bignell, J Lancaster, S Swift, S Seal, J Mangion, N Collins, ...
Nature 378 (6559), 789-792, 1995
49521995
Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case series unselected for family history: a combined analysis of 22 studies
A Antoniou, PDP Pharoah, S Narod, HA Risch, JE Eyfjord, JL Hopper, ...
The American Journal of Human Genetics 72 (5), 1117-1130, 2003
48902003
Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families
D Ford, DF Easton, M Stratton, S Narod, D Goldgar, P Devilee, DT Bishop, ...
The American Journal of Human Genetics 62 (3), 676-689, 1998
39891998
Patterns of somatic mutation in human cancer genomes
C Greenman, P Stephens, R Smith, GL Dalgliesh, C Hunter, G Bignell, ...
Nature 446 (7132), 153-158, 2007
38122007
Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers
KB Kuchenbaecker, JL Hopper, DR Barnes, KA Phillips, TM Mooij, ...
Jama 317 (23), 2402-2416, 2017
30472017
Localization of a Breast Cancer Susceptibility Gene, BRCA2, to Chromosome 13q12-13
R Wooster, SL Neuhausen, J Mangion, Y Quirk, D Ford, N Collins, ...
Science 265 (5181), 2088-2090, 1994
28791994
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar, C Vacher, Z Berger, JE Davies, S Luo, LG Oroz, F Scaravilli, ...
Nature genetics 36 (6), 585-595, 2004
28482004
Genome-wide association study identifies novel breast cancer susceptibility loci
DF Easton, KA Pooley, AM Dunning, PDP Pharoah, D Thompson, ...
Nature 447 (7148), 1087-1093, 2007
28462007
Risks of cancer in BRCA1-mutation carriers
D Ford, DF Easton, DT Bishop, SA Narod, DE Goldgar
The Lancet 343 (8899), 692-695, 1994
24901994
Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.
DF Easton, D Ford, DT Bishop
American journal of human genetics 56 (1), 265, 1995
22051995
Polychemotherapy for early breast cancer: an overview of the randomised trials
Early Breast Cancer Trialists' Collaborative Group
The Lancet 352 (9132), 930-942, 1998
21601998
The landscape of cancer genes and mutational processes in breast cancer
PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ...
Nature 486 (7403), 400-404, 2012
19472012
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1925*2020
Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.
DF Easton, DT Bishop, D Ford, GP Crockford
American journal of human genetics 52 (4), 678, 1993
17841993
The evolutionary history of lethal metastatic prostate cancer
G Gundem, P Van Loo, B Kremeyer, LB Alexandrov, JMC Tubio, ...
Nature 520 (7547), 353-357, 2015
15082015
Cancer incidence in BRCA1 mutation carriers
D Thompson, DF Easton
Journal of the National Cancer Institute 94 (18), 1358-1365, 2002
15082002
Association analysis identifies 65 new breast cancer risk loci
K Michailidou, S Lindström, J Dennis, J Beesley, S Hui, S Kar, A Lemaçon, ...
Nature 551 (7678), 92-94, 2017
14662017
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
1958 Birth Cohort Controls: Jones Richard W 18 McArdle Wendy L 18 Ring Susan ...
Nature genetics 39 (11), 1329-1337, 2007
14522007
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
14232015
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