| NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights SM Gough, CI Slape, PD Aplan Blood, The Journal of the American Society of Hematology 118 (24), 6247-6257, 2011 | 360 | 2011 |
| Abstract P5-04-18: ARV-471, an oral estrogen receptor PROTAC degrader for breast cancer JJ Flanagan, Y Qian, SM Gough, M Andreoli, M Bookbinder, G Cadelina, ... Cancer research 79 (4_Supplement), P5-04-18-P5-04-18, 2019 | 148 | 2019 |
| The discovery of ARV-471, an orally bioavailable estrogen receptor degrading PROTAC for the treatment of patients with breast cancer LB Snyder, JJ Flanagan, Y Qian, SM Gough, M Andreoli, M Bookbinder, ... Cancer Res 81 (13), 44, 2021 | 101 | 2021 |
| Age-related epigenetic drift in the pathogenesis of MDS and AML S Maegawa, SM Gough, N Watanabe-Okochi, Y Lu, N Zhang, RJ Castoro, ... Genome research 24 (4), 580-591, 2014 | 95 | 2014 |
| NUP98–PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function SM Gough, F Lee, F Yang, RL Walker, YJ Zhu, M Pineda, M Onozawa, ... Cancer discovery 4 (5), 564-577, 2014 | 84 | 2014 |
| Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome YJ Chung, C Robert, SM Gough, FV Rassool, PD Aplan Leukemia research 38 (1), 95-102, 2014 | 64 | 2014 |
| Cloning and characterization of a novel β integrin-related cDNA coding for the protein TIED (“ten β integrin EGF-like repeat domains”) that maps to chromosome band 13q33: a … RW Berg, E Leung, S Gough, C Morris, WP Yao, SX Wang, J Ni, ... Genomics 56 (2), 169-178, 1999 | 57 | 1999 |
| Cloning, sequence analysis, and chromosomal localization of the novel human integrin α11 subunit (ITGA11) K Lehnert, J Ni, E Leung, SM Gough, A Weaver, WP Yao, D Liu, SX Wang, ... Genomics 60 (2), 179-187, 1999 | 49 | 1999 |
| Release and clinical significance of soluble CD83 in chronic lymphocytic leukemia BD Hock, LJ Fernyhough, SM Gough, A Steinkasserer, AG Cox, ... Leukemia research 33 (8), 1089-1095, 2009 | 39 | 2009 |
| The small GTPase RAC3 gene is located within chromosome band 17q25. 3 outside and telomeric of a region commonly deleted in breast and ovarian tumours CM Morris, L Haataja, M McDonald, S Gough, D Markie, J Groffen, ... Cytogenetics and cell genetics 89 (1-2), 18-23, 2000 | 38 | 2000 |
| Oral estrogen receptor PROTAC vepdegestrant (ARV-471) is highly efficacious as monotherapy and in combination with CDK4/6 or PI3K/mTOR pathway inhibitors in preclinical ER+ … SM Gough, JJ Flanagan, J Teh, M Andreoli, E Rousseau, M Pannone, ... Clinical Cancer Research 30 (16), 3549-3563, 2024 | 35 | 2024 |
| Mechanistic insights into chromatin targeting by leukemic NUP98-PHF23 fusion Y Zhang, Y Guo, SM Gough, J Zhang, KR Vann, K Li, L Cai, X Shi, ... Nature Communications 11 (1), 3339, 2020 | 26 | 2020 |
| The integrin α10 subunit: Expression pattern, partial gene structure, and chromosomal localization K Lehnert, J Ni, E Leung, S Gough, CM Morris, D Liu, SX Wang, ... Cytogenetics and cell genetics 87 (3-4), 238-244, 1999 | 25 | 1999 |
| Progenitor B-1 B-cell acute lymphoblastic leukemia is associated with collaborative mutations in 3 critical pathways SM Gough, L Goldberg, M Pineda, RL Walker, YJ Zhu, S Bilke, YJ Chung, ... Blood advances 1 (20), 1749-1759, 2017 | 22 | 2017 |
| NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function. Cancer Discov. 2014; 4 (5): 564 … SM Gough, F Lee, F Yang, RL Walker, YJ Zhu, M Pineda, M Onozawa, ... CD-13-0419, 0 | 14 | |
| Methods of treating breast cancer with tetrahydronaphthalene derivatives as estrogen receptor degraders AP Crew, J Flanagan, SM Gough, J Royal III, MD Moore, Y Qian, ... US Patent 12,208,095, 2025 | 10 | 2025 |
| Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance L Goldberg, SM Gough, F Lee, C Dang, RL Walker, YJ Zhu, S Bilke, ... Genes, Chromosomes and Cancer 56 (6), 472-483, 2017 | 10 | 2017 |
| Depletion of Cytotoxic T-Cells Does Not Protect NUP98-HOXD13 Mice from Myelodysplastic Syndrome but Reveals a Modest Tumor Immunosurveillance Effect SM Gough, YJ Chung, PD Aplan PLoS One 7 (5), e36876, 2012 | 9 | 2012 |
| Refined physical map of the human PAX2/HOX11/NFKB2 cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13.3-q21.1 SM Gough, M McDonald, XN Chen, JR Korenberg, A Neri, T Kahn, ... BMC genomics 4, 1-12, 2003 | 7 | 2003 |
| Abstract P4-04-04: Identification and development of oral estrogen receptor PROTAC degraders for breast cancer JJ Flanagan, Y Qian, SM Gough, M Andreoli, M Bookbinder, J Bradley, ... Cancer Research 78 (4_Supplement), P4-04-04-P4-04-04, 2018 | 6 | 2018 |
peter d. aplanSenior Investigator national institutes of healthE-mail megerősítve itt: mail.nih.gov
