APOBEC3B is an enzymatic source of mutation in breast cancer MB Burns, L Lackey, MA Carpenter, A Rathore, AM Land, B Leonard, ... Nature 494 (7437), 366-370, 2013 | 920 | 2013 |
Genetic variants near TIMP3 and high-density lipoprotein–associated loci influence susceptibility to age-related macular degeneration W Chen, D Stambolian, AO Edwards, KE Branham, M Othman, ... Proceedings of the National Academy of Sciences 107 (16), 7401-7406, 2010 | 622 | 2010 |
APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo MT Liddament, WL Brown, AJ Schumacher, RS Harris Current Biology 14 (15), 1385-1391, 2004 | 563 | 2004 |
Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction EW Refsland, MD Stenglein, K Shindo, JS Albin, WL Brown, RS Harris Nucleic acids research 38 (13), 4274-4284, 2010 | 420 | 2010 |
Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1 JF Hultquist, JA Lengyel, EW Refsland, RS LaRue, L Lackey, WL Brown, ... Journal of virology 85 (21), 11220-11234, 2011 | 416 | 2011 |
Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration JL Mbisa, R Barr, JA Thomas, N Vandegraaff, IJ Dorweiler, ... Journal of virology 81 (13), 7099-7110, 2007 | 347 | 2007 |
E2-2 protein and Fuchs's corneal dystrophy KH Baratz, N Tosakulwong, E Ryu, WL Brown, K Branham, W Chen, ... New England Journal of Medicine 363 (11), 1016-1024, 2010 | 328 | 2010 |
APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma B Leonard, SN Hart, MB Burns, MA Carpenter, NA Temiz, A Rathore, ... Cancer research 73 (24), 7222-7231, 2013 | 187 | 2013 |
Subcellular localization of the APOBEC3 proteins during mitosis and implications for genomic DNA deamination L Lackey, EK Law, WL Brown, RS Harris Cell Cycle 12 (5), 762-772, 2013 | 185 | 2013 |
Genetic control of the alternative pathway of complement in humans and age-related macular degeneration LA Hecker, AO Edwards, E Ryu, N Tosakulwong, KH Baratz, WL Brown, ... Human molecular genetics 19 (1), 209-215, 2010 | 180 | 2010 |
The DNA deaminase activity of human APOBEC3G is required for Ty1, MusD, and human immunodeficiency virus type 1 restriction AJ Schumacher, G Haché, DA MacDuff, WL Brown, RS Harris Journal of virology 82 (6), 2652-2660, 2008 | 180 | 2008 |
Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A MA Carpenter, M Li, A Rathore, L Lackey, EK Law, AM Land, B Leonard, ... Journal of Biological Chemistry 287 (41), 34801-34808, 2012 | 162 | 2012 |
The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers B Leonard, JL McCann, GJ Starrett, L Kosyakovsky, EM Luengas, ... Cancer research 75 (21), 4538-4547, 2015 | 150 | 2015 |
First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G M Li, SMD Shandilya, MA Carpenter, A Rathore, WL Brown, AL Perkins, ... ACS chemical biology 7 (3), 506-517, 2012 | 149 | 2012 |
RNA bacteriophage capsid-mediated drug delivery and epitope presentation WL Brown, RA Mastico, M Wu, KG Heal, CJ Adams, JB Murray, ... Intervirology 45 (4-6), 371-380, 2003 | 145 | 2003 |
Epstein–Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity AZ Cheng, J Yockteng-Melgar, MC Jarvis, N Malik-Soni, I Borozan, ... Nature microbiology 4 (1), 78-88, 2019 | 132 | 2019 |
Cell-specific delivery of bacteriophage-encapsidated ricin A chain M Wu, WL Brown, PG Stockley Bioconjugate chemistry 6 (5), 587-595, 1995 | 132 | 1995 |
APOBEC3B and AID have similar nuclear import mechanisms L Lackey, ZL Demorest, AM Land, JF Hultquist, WL Brown, RS Harris Journal of molecular biology 419 (5), 301-314, 2012 | 118 | 2012 |
The local dinucleotide preference of APOBEC3G can be altered from 5′-CC to 5′-TC by a single amino acid substitution A Rathore, MA Carpenter, Ö Demir, T Ikeda, M Li, NM Shaban, EK Law, ... Journal of molecular biology 425 (22), 4442-4454, 2013 | 116 | 2013 |
Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity EW Refsland, JF Hultquist, EM Luengas, T Ikeda, NM Shaban, EK Law, ... PLoS genetics 10 (11), e1004761, 2014 | 114 | 2014 |