Der p 1 facilitates transepithelial allergen delivery by disruption of tight junctions H Wan, HL Winton, C Soeller, ER Tovey, DC Gruenert, PJ Thompson, ... The Journal of clinical investigation 104 (1), 123-133, 1999 | 1006 | 1999 |
Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1) T Hamada, WHI McLean, M Ramsay, GHS Ashton, A Nanda, T Jenkins, ... Human molecular genetics 11 (7), 833-840, 2002 | 385 | 2002 |
The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus H Wan, HL Winton, C Soeller, GW Taylor, DC Gruenert, PJ Thompson, ... Clinical & Experimental Allergy 31 (2), 279-294, 2001 | 339 | 2001 |
Quantitative structural and biochemical analyses of tight junction dynamics following exposure of epithelial cells to house dust mite allergen Der p 1 Wan, Winton, Soeller, Gruenert, Cannell, Garrod, Robinson Clinical & Experimental Allergy 30 (5), 685-698, 2000 | 237 | 2000 |
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation E Gemenetzidis, A Bose, AM Riaz, T Chaplin, BD Young, M Ali, D Sugden, ... PloS one 4 (3), e4849, 2009 | 228 | 2009 |
Tight junction properties of the immortalized human bronchial epithelial cell lines Calu-3 and 16HBE14o H Wan, HL Winton, C Soeller, GA Stewart, PJ Thompson, DC Gruenert, ... European Respiratory Journal 15 (6), 1058-1068, 2000 | 218 | 2000 |
Compound heterozygosity for non-sense and mis-sense mutations in desmoplakin underlies skin fragility/woolly hair syndrome NV Whittock, H Wan, RAJ Eady, SM Morley, MC Garzon, L Kristal, P Hyde, ... Journal of Investigative Dermatology 118 (2), 232-238, 2002 | 170 | 2002 |
Lack of plakophilin 1 increases keratinocyte migration and reduces desmosome stability AP South, H Wan, MG Stone, PJC Dopping-Hepenstal, PE Purkis, ... Journal of cell science 116 (16), 3303-3314, 2003 | 155 | 2003 |
Cell lines of pulmonary and non‐pulmonary origin as tools to study the effects of house dust mite proteinases on the regulation of epithelial permeability Winton, Wan, Cannell, Gruenert, J Thompson, Garrod, Robinson Clinical & Experimental Allergy 28 (10), 1273-1285, 1998 | 140 | 1998 |
Induction of human epithelial stem/progenitor expansion by FOXM1 E Gemenetzidis, D Elena-Costea, EK Parkinson, A Waseem, H Wan, ... Cancer research 70 (22), 9515-9526, 2010 | 129 | 2010 |
Class specific inhibition of house dust mite proteinases which cleave cell adhesion, induce cell death and which increase the permeability of lung epithelium HL Winton, H Wan, MB Cannell, PJ Thompson, DR Garrod, GA Stewart, ... British journal of pharmacology 124 (6), 1048-1059, 1998 | 121 | 1998 |
Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes H Wan, MG Stone, C Simpson, LE Reynolds, JF Marshall, IR Hart, ... Journal of cell science 116 (20), 4239-4248, 2003 | 120 | 2003 |
Frameshift mutation in the V2 domain of human keratin 1 results in striate palmoplantar keratoderma NV Whittock, FJ Smith, WHI McLean, H Wan, R Mallipeddi, WA Griffiths, ... Journal of investigative dermatology 118 (5), 838-844, 2002 | 118 | 2002 |
Epithelial secretion of C3 promotes colonization of the upper urinary tract by Escherichia coli T Springall, NS Sheerin, K Abe, VM Holers, H Wan, SH Sacks Nature medicine 7 (7), 801-806, 2001 | 110 | 2001 |
Striate palmoplantar keratoderma arising from desmoplakin and desmoglein 1 mutations is associated with contrasting perturbations of desmosomes and the keratin filament network H Wan, PJC Dopping‐Hepenstal, MJ Gratian, MG Stone, G Zhu, ... British Journal of Dermatology 150 (5), 878-891, 2004 | 79 | 2004 |
Non‐junctional human desmoglein 3 acts as an upstream regulator of Src in E‐cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris SM Tsang, L Brown, K Lin, L Liu, K Piper, EA O'Toole, R Grose, IR Hart, ... The Journal of Pathology 227 (1), 81-93, 2012 | 77 | 2012 |
Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src SM Tsang, L Liu, MT Teh, A Wheeler, R Grose, IR Hart, DR Garrod, ... PLoS One 5 (12), e14211, 2010 | 76 | 2010 |
Desmoglein 3 promotes cancer cell migration and invasion by regulating activator protein 1 and protein kinase C-dependent-Ezrin activation L Brown, A Waseem, IN Cruz, J Szary, E Gunic, T Mannan, M Unadkat, ... Oncogene 33 (18), 2363-2374, 2014 | 74 | 2014 |
Desmoglein 3 acting as an upstream regulator of Rho GTPases, Rac-1/Cdc42 in the regulation of actin organisation and dynamics SM Tsang, L Brown, H Gadmor, L Gammon, F Fortune, A Wheeler, H Wan Experimental cell research 318 (18), 2269-2283, 2012 | 59 | 2012 |
Increased keratinocyte proliferation initiated through downregulation of desmoplakin by RNA interference H Wan, AP South, IR Hart Experimental cell research 313 (11), 2336-2344, 2007 | 59 | 2007 |