| Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome BC Capell, MR Erdos, JP Madigan, JJ Fiordalisi, R Varga, KN Conneely, ... Proceedings of the National Academy of Sciences 102 (36), 12879-12884, 2005 | 483 | 2005 |
| Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification PJ Roberts, N Mitin, PJ Keller, EJ Chenette, JP Madigan, RO Currin, ... Journal of Biological Chemistry 283 (37), 25150-25163, 2008 | 442 | 2008 |
| Say no to DMSO: dimethylsulfoxide inactivates cisplatin, carboplatin, and other platinum complexes MD Hall, KA Telma, KE Chang, TD Lee, JP Madigan, JR Lloyd, ... Cancer research 74 (14), 3913-3922, 2014 | 384 | 2014 |
| DNA double‐strand break‐induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation‐induced apoptosis JP Madigan, HL Chotkowski, RL Glaser Nucleic acids research 30 (17), 3698-3705, 2002 | 332 | 2002 |
| Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity*♦ L Esser, F Zhou, KM Pluchino, J Shiloach, J Ma, W Tang, C Gutierrez, ... Journal of Biological Chemistry 292 (2), 446-461, 2017 | 202 | 2017 |
| Anti-inflammatory effects of freeze-dried black raspberry powder in ulcerative colitis DC Montrose, NA Horelik, JP Madigan, GD Stoner, LS Wang, RS Bruno, ... Carcinogenesis 32 (3), 343-350, 2011 | 174 | 2011 |
| Histone H2A. Z is widely but nonrandomly distributed in chromosomes of Drosophila melanogaster TJ Leach, M Mazzeo, HL Chotkowski, JP Madigan, MG Wotring, ... Journal of Biological Chemistry 275 (30), 23267-23272, 2000 | 171 | 2000 |
| Ibuprofen inhibits activation of nuclear β-catenin in human colon adenomas and induces the phosphorylation of GSK-3β EJ Greenspan, JP Madigan, LA Boardman, DW Rosenberg Cancer Prevention Research 4 (1), 161-171, 2011 | 119 | 2011 |
| Regulation of Rnd3 localization and function by protein kinase Cα-mediated phosphorylation JP Madigan, BO Bodemann, DC Brady, BJ Dewar, PJ Keller, M Leitges, ... Biochemical Journal 424 (1), 153-161, 2009 | 83 | 2009 |
| Genome-wide analysis of the relationship between transcriptional regulation by Rpd3p and the histone H3 and H4 amino termini in budding yeast N Sabet, S Volo, C Yu, JP Madigan, RH Morse Molecular and cellular biology 24 (20), 8823-8833, 2004 | 70 | 2004 |
| Inhibition of glutathione peroxidase mediates the collateral sensitivity of multidrug-resistant cells to tiopronin MD Hall, TS Marshall, ADT Kwit, LMM Jenkins, AE Dulcey, JP Madigan, ... Journal of Biological Chemistry 289 (31), 21473-21489, 2014 | 67 | 2014 |
| Global and specific transcriptional repression by the histone H3 amino terminus in yeast N Sabet, F Tong, JP Madigan, S Volo, MM Smith, RH Morse Proceedings of the National Academy of Sciences 100 (7), 4084-4089, 2003 | 63 | 2003 |
| The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis DC Brady, JK Alan, JP Madigan, AS Fanning, AD Cox Molecular and Cellular Biology 29 (4), 1035-1049, 2009 | 58 | 2009 |
| The protein phosphatase 2A inhibitor LB100 sensitizes ovarian carcinoma cells to cisplatin-mediated cytotoxicity KE Chang, BR Wei, JP Madigan, MD Hall, RM Simpson, Z Zhuang, ... Molecular cancer therapeutics 14 (1), 90-100, 2015 | 55 | 2015 |
| Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53 SAF Morad, JP Madigan, JC Levin, N Abdelmageed, R Karimi, ... Biochemical pharmacology 85 (8), 1057-1065, 2013 | 52 | 2013 |
| Src-mediated phosphorylation of the tyrosine phosphatase PRL-3 is required for PRL-3 promotion of Rho activation, motility and invasion JJ Fiordalisi, BJ Dewar, LM Graves, JP Madigan, AD Cox PloS one 8 (5), e64309, 2013 | 45 | 2013 |
| A role for ceramide glycosylation in resistance to oxaliplatin in colorectal cancer JP Madigan, RW Robey, JE Poprawski, H Huang, CJ Clarke, ... Experimental cell research 388 (2), 111860, 2020 | 38 | 2020 |
| A gene expression signature associated with overall survival in patients with hepatocellular carcinoma suggests a new treatment strategy JP Gillet, JB Andersen, JP Madigan, S Varma, RK Bagni, K Powell, ... Molecular pharmacology 89 (2), 263-272, 2016 | 32 | 2016 |
| Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL PS Souza, JP Madigan, JP Gillet, K Kapoor, SV Ambudkar, RC Maia, ... Experimental cell research 336 (2), 318-328, 2015 | 29 | 2015 |
| Vitamin D resistance and colon cancer prevention C Giardina, JP Madigan, CA Godman Tierney, B M. Brenner, ... Carcinogenesis 33 (3), 475-482, 2012 | 27 | 2012 |
