Hhal methyltransferase flips its target base out of the DNA helix S Klimasauskas, S Kumar, RJ Roberts, X Cheng Cell 76 (2), 357-369, 1994 | 1291 | 1994 |
The DNA (cytosine-5) methyltransferases S Kumar, X Cheng, S Klimasauskas, S Mi, J Posfai, RJ Roberts, ... Nucleic acids research 22 (1), 1, 1994 | 576 | 1994 |
5-hmC in the brain is abundant in synaptic genes and shows differences at the exon-intron boundary T Khare, S Pai, K Koncevicius, M Pal, E Kriukiene, Z Liutkeviciute, M Irimia, ... Nature structural & molecular biology 19 (10), 1037-1043, 2012 | 308 | 2012 |
2-Aminopurine as a fluorescent probe for DNA base flipping by methyltransferases B Holz, E Weinhold, S Klimasauskas, S Serva Nucleic acids research 26 (4), 1076-1083, 1998 | 285 | 1998 |
Direct transfer of extended groups from synthetic cofactors by DNA methyltransferases C Dalhoff, G Lukinavičius, S Klimas̆auskas, E Weinhold Nature chemical biology 2 (1), 31-32, 2006 | 265 | 2006 |
Processive methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase G Vilkaitis, I Suetake, S Klimašauskas, S Tajima Journal of Biological Chemistry 280 (1), 64-72, 2005 | 253 | 2005 |
Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures forHhaI methyltransferase-DNA-AdoHcy complexes M O'Gara, S Klimaŝauskas, RJ Roberts, X Cheng Journal of molecular biology 261 (5), 634-645, 1996 | 221 | 1996 |
A new tool for biotechnology: AdoMet-dependent methyltransferases S Klimašauskas, E Weinhold Trends in biotechnology 25 (3), 99-104, 2007 | 194 | 2007 |
MHhal binds tightly to substrates containing mismatches at the target base S Klimašauskas, RJ Roberts Nucleic acids research 23 (8), 1388-1395, 1995 | 193 | 1995 |
Sequence motifs characteristic of DNA [cytosine-N4] methyltransferases: similarity to adenine and cytosine-C5 DNA-methylases S Klimasauskas, A Timinskas, M Saulius, D Butkiene, V Butkus, ... Nucleic acids research 17 (23), 9823-9832, 1989 | 185 | 1989 |
Cytosine-5-methyltransferases add aldehydes to DNA Z Liutkevičiūtė, G Lukinavičius, V Masevičius, D Daujotytė, ... Nature chemical biology 5 (6), 400-402, 2009 | 182 | 2009 |
Targeted labeling of DNA by methyltransferase-directed transfer of activated groups (mTAG) G Lukinavičius, V Lapienė, Z Staševskij, C Dalhoff, E Weinhold, ... Journal of the American Chemical Society 129 (10), 2758-2759, 2007 | 162 | 2007 |
An adversarial DNA N6-methyladenine-sensor network preserves polycomb silencing SM Kweon, Y Chen, E Moon, K Kvederaviciutė, S Klimasauskas, ... Molecular cell 74 (6), 1138-1147. e6, 2019 | 148 | 2019 |
Dynamic modes of the flipped‐out cytosine during HhaI methyltransferase–DNA interactions in solution S Klimašauskas, T Szyperski, S Serva, K Wüthrich The EMBO journal, 1998 | 144 | 1998 |
The mechanism of DNA cytosine-5 methylation: Kinetic and mutational dissection of HhaI methyltransferase G Vilkaitis, S Serva, E Weinhold, S Klimašauskas Journal of Biological Chemistry 276 (24), 20924-20934, 2001 | 141 | 2001 |
Cytosine modification in DNA by BcnI methylase yields N4-methylcytosine A Janulaitis, S Klimasauskas, M Petrusyte, V Butkus FEBS Lett 161 (1), 131-134, 1983 | 140 | 1983 |
Enhanced chemical stability of AdoMet analogues for improved methyltransferase-directed labeling of DNA G Lukinavičius, M Tomkuvienė, V Masevičius, S Klimašauskas ACS chemical biology 8 (6), 1134-1139, 2013 | 125 | 2013 |
DNA fluorocode: A single molecule, optical map of DNA with nanometre resolution RK Neely, P Dedecker, J Hotta, G Urbanavičiūtė, S Klimašauskas, ... Chemical science 1 (4), 453-460, 2010 | 119 | 2010 |
Synthesis of S-adenosyl-L-methionine analogs and their use for sequence-specific transalkylation of DNA by methyltransferases C Dalhoff, G Lukinavičius, S Klimašauskas, E Weinhold Nature protocols 1 (4), 1879-1886, 2006 | 115 | 2006 |
Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M. HhaI–DNA complexes RK Neely, D Daujotyte, S Grazulis, SW Magennis, DTF Dryden, ... Nucleic Acids Research 33 (22), 6953-6960, 2005 | 113 | 2005 |