| mTOR-and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity SC Cheng, J Quintin, RA Cramer, KM Shepardson, S Saeed, V Kumar, ... science 345 (6204), 1250684, 2014 | 2031 | 2014 |
| Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis SC Cheng, BP Scicluna, RJW Arts, MS Gresnigt, E Lachmandas, ... Nature immunology 17 (4), 406-413, 2016 | 569 | 2016 |
| Mitochondrial hyperpolarization during chronic complex I inhibition is sustained by low activity of complex II, III, IV and V M Forkink, GR Manjeri, DC Liemburg-Apers, E Nibbeling, M Blanchard, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1837 (8), 1247-1256, 2014 | 119 | 2014 |
| How to deal with oxygen radicals stemming from mitochondrial fatty acid oxidation D Speijer, GR Manjeri, R Szklarczyk Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014 | 72 | 2014 |
| Complex I disorders: causes, mechanisms, and development of treatment strategies at the cellular level F Valsecchi, WJH Koopman, GR Manjeri, RJ Rodenburg, JAM Smeitink, ... Developmental disabilities research reviews 16 (2), 175-182, 2010 | 68 | 2010 |
| Pharmacological targeting of mitochondrial complex I deficiency: the cellular level and beyond P Roestenberg, GR Manjeri, F Valsecchi, JAM Smeitink, PHGM Willems, ... Mitochondrion 12 (1), 57-65, 2012 | 53 | 2012 |
| Skeletal muscle mitochondria of NDUFS4−/− mice display normal maximal pyruvate oxidation and ATP production MT Alam, GR Manjeri, RJ Rodenburg, JAM Smeitink, RA Notebaart, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1847 (6-7), 526-533, 2015 | 35 | 2015 |
| Increased mitochondrial ATP production capacity in brain of healthy mice and a mouse model of isolated complex I deficiency after isoflurane anesthesia GR Manjeri, RJ Rodenburg, L Blanchet, S Roelofs, LG Nijtmans, ... Journal of Inherited Metabolic Disease 39, 59-65, 2016 | 21 | 2016 |
| Isoflurane anesthetic hypersensitivity and progressive respiratory depression in a mouse model with isolated mitochondrial complex I deficiency S Roelofs, GR Manjeri, PH Willems, GJ Scheffer, JA Smeitink, JJ Driessen Journal of anesthesia 28, 807-814, 2014 | 13 | 2014 |
| Phenylarsine oxide interferes with the death inducing signaling complex and inhibits tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced apoptosis XM Sun, A Canda-Sanchez, GR Manjeri, GM Cohen, MJ Pinkoski Experimental cell research 315 (14), 2453-2462, 2009 | 6 | 2009 |
| View metadata, citation and similar papers at core. ac. uk A DE, JFM COOPER, T DA POR Signo y Seña 28 (28), 211-235, 2015 | 2 | 2015 |
| Glycolytic Metabolism is Differentially Coupled to Proliferative Potential and Morphodynamic Capacity in RAW 264.7 and Mafb/C-Maf Deficient Macrophage Lineages G Helden, MJP Wijers, F Oerlemans, GR Manjeri, JA Fransen, B Wieringa | 1 | 2015 |
| Characterization of the Ndufs4-/-model to evaluate a novel therapeutic strategy towards mitochondrial dysfunction GR Manjeri Sl: sn, 2017 | | 2017 |
| Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. CSC Cheng ShihChin, BP Scicluna, RJW Arts, MS Gresnigt, ... | | 2016 |
| Cholesterol biosynthesis compensates for the impaired redox state caused by mitochondrial complex I-deficiency TJJ Schirris, S Rossell, R de Haas, SJCM Frambach, GR Manjeri, ... on-and off-target mitochondrial drug effects by systems medicine, 145, 2016 | | 2016 |
| How to deal with oxygen radicals stemming from D Speijer, GR Manjeri, R Szklarczyk | | 2014 |
| View metadata, citation and similar papers at core. ac. uk G Manjeri, S Roelofs, A Janssen, L Blanchet, J Driessen, R Rodenburg, ... future 1659, 115-120, 2004 | | 2004 |
| Tissue specific metabolic consequences of isolated mitochondrial complex I deficiency in mice G Manjeri, S Roelofs, A Janssen, L Blanchet, J Driessen, R Rodenburg, ... Biochim. Biophys. Acta 2010, 659-663, 1797 | | 1797 |
| Complex I deficiency: Causes, consequences and treatment options with focus towards the NDUFS4 subunit P Roestenberg, GR Manjeri, F Valsecchi Characterization of the Ndufs4-/-model to evaluate a novel therapeutic …, 0 | | |
| Biochemical characterization of the oxidative phosphorylation system in tissues of high energy demand in a mouse model of isolated complex I deficiency GR Manjeri Characterization of the Ndufs4-/-model to evaluate a novel therapeutic …, 0 | | |
Prof. dr. Jan A.M. SmeitinkProfessor in Mitochondrial MedicineE-mail megerősítve itt: radboudumc.nl