| Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing AW Fjorback, M Seaman, C Gustafsen, A Mehmedbasic, S Gokool, C Wu, ... Journal of Neuroscience 32 (4), 1467-1480, 2012 | 296 | 2012 |
| Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA MS Nielsen, C Gustafsen, P Madsen, JR Nyengaard, G Hermey, O Bakke, ... Molecular and cellular biology 27 (19), 6842-6851, 2007 | 224 | 2007 |
| The hypercholesterolemia-risk gene SORT1 facilitates PCSK9 secretion C Gustafsen, M Kjolby, M Nyegaard, M Mattheisen, J Lundhede, ... Cell metabolism 19 (2), 310-318, 2014 | 200 | 2014 |
| Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein C Gustafsen, S Glerup, LT Pallesen, D Olsen, OM Andersen, A Nykjær, ... Journal of Neuroscience 33 (1), 64-71, 2013 | 121 | 2013 |
| The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain AS Carlo, C Gustafsen, G Mastrobuoni, MS Nielsen, T Burgert, D Hartl, ... Journal of Neuroscience 33 (1), 358-370, 2013 | 117 | 2013 |
| Heparan sulfate proteoglycans present PCSK9 to the LDL receptor C Gustafsen, D Olsen, J Vilstrup, S Lund, A Reinhardt, N Wellner, ... Nature communications 8 (1), 503, 2017 | 113 | 2017 |
| SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia S Glerup, D Olsen, CB Vaegter, C Gustafsen, SS Sjoegaard, G Hermey, ... Neuron 82 (5), 1074-1087, 2014 | 100 | 2014 |
| SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET S Glerup, M Lume, D Olsen, JR Nyengaard, CB Vaegter, C Gustafsen, ... Cell reports 3 (1), 186-199, 2013 | 72 | 2013 |
| Proneurotrophin‐3 may induce Sortilin‐dependent death in inner ear neurons J Tauris, C Gustafsen, EI Christensen, P Jansen, A Nykjaer, ... European Journal of Neuroscience 33 (4), 622-631, 2011 | 60 | 2011 |
| Different motifs regulate trafficking of SorCS1 isoforms MS Nielsen, SJ Keat, JW Hamati, P Madsen, JJ Gutzmann, A Engelsberg, ... Traffic 9 (6), 980-994, 2008 | 58 | 2008 |
| Increased serum levels of sortilin are associated with depression and correlated with BDNF and VEGF HN Buttenschøn, D Demontis, M Kaas, B Elfving, S Mølgaard, ... Translational psychiatry 5 (11), e677-e677, 2015 | 52 | 2015 |
| Targeting PCSK9 to tackle cardiovascular disease S Hummelgaard, JP Vilstrup, C Gustafsen, S Glerup, K Weyer Pharmacology & therapeutics 249, 108480, 2023 | 50 | 2023 |
| SorLA complement-type repeat domains protect the amyloid precursor protein against processing A Mehmedbasic, SK Christensen, J Nilsson, U Rüetschi, C Gustafsen, ... Journal of Biological Chemistry 290 (6), 3359-3376, 2015 | 50 | 2015 |
| GGA autoinhibition revisited JF Cramer, C Gustafsen, MA Behrens, CLP Oliveira, JS Pedersen, ... Traffic 11 (2), 259-273, 2010 | 40 | 2010 |
| The Lotus japonicus ndxgene family is involved in nodule function and maintenance M Grønlund, C Gustafsen, A Roussis, D Jensen, LP Nielsen, KA Marcker, ... Plant Molecular Biology 52, 303-316, 2003 | 18 | 2003 |
| PAK kinases target sortilin and modulate its sorting LT Pallesen, C Gustafsen, JF Cramer, SV Petersen, SS Thirup, P Madsen, ... Molecular and cellular biology 40 (3), e00411-19, 2020 | 17 | 2020 |
| Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome CK Skeby, S Hummelgaard, C Gustafsen, F Petrillo, KP Frederiksen, ... Kidney International 104 (4), 754-768, 2023 | 16 | 2023 |
| Association between circulating proprotein convertase subtilisin/kexin type 9 levels and prognosis in patients with severe chronic kidney disease LD Rasmussen, M Bøttcher, P Ivarsen, HS Jørgensen, M Nyegaard, ... Nephrology Dialysis Transplantation 35 (4), 632-639, 2020 | 13 | 2020 |
| HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA P Madsen, TJ Isaksen, P Siupka, AE Tóth, M Nyegaard, C Gustafsen, ... Scientific Reports 9 (1), 611, 2019 | 13 | 2019 |
| PCSK9 deficiency alters brain lipid composition without affecting brain development and function A Pärn, D Olsen, J Tuvikene, M Kaas, E Borisova, M Bilgin, M Elhauge, ... Frontiers in molecular neuroscience 15, 1084633, 2023 | 9 | 2023 |
