| mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome SC Johnson, ME Yanos, EB Kayser, A Quintana, M Sangesland, ... Science 342 (6165), 1524-1528, 2013 | 551 | 2013 |
| A comprehensive analysis of replicative lifespan in 4,698 single-gene deletion strains uncovers conserved mechanisms of aging MA McCormick, JR Delaney, M Tsuchiya, S Tsuchiyama, A Shemorry, ... Cell metabolism 22 (5), 895-906, 2015 | 269 | 2015 |
| H3K36 methylation promotes longevity by enhancing transcriptional fidelity P Sen, W Dang, G Donahue, J Dai, J Dorsey, X Cao, W Liu, K Cao, ... Genes & development 29 (13), 1362-1376, 2015 | 241 | 2015 |
| Molecular mechanisms underlying genotype‐dependent responses to dietary restriction J Schleit, SC Johnson, CF Bennett, M Simko, N Trongtham, A Castanza, ... Aging cell 12 (6), 1050-1061, 2013 | 180 | 2013 |
| pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast C Murakami, JR Delaney, A Chou, D Carr, J Schleit, GL Sutphin, EH An, ... Cell cycle 11 (16), 3087-3096, 2012 | 80 | 2012 |
| Yeast replicative aging: a paradigm for defining conserved longevity interventions BM Wasko, M Kaeberlein FEMS yeast research 14 (1), 148-159, 2014 | 78 | 2014 |
| Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate BM Wasko, A Dudakovic, RJ Hohl The Journal of pharmacology and experimental therapeutics 337 (2), 540-546, 2011 | 73 | 2011 |
| Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae JR Delaney, C Murakami, A Chou, D Carr, J Schleit, GL Sutphin, EH An, ... Experimental gerontology 48 (10), 1006-1013, 2013 | 66 | 2013 |
| Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation AJ Wiemer, SY Jose, LW Shull, RJ Barney, BM Wasko, KM Lamb, RJ Hohl, ... Bioorganic & medicinal chemistry 16 (7), 3652-3660, 2008 | 64 | 2008 |
| Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans CF Bennett, JJ Kwon, C Chen, J Russell, K Acosta, N Burnaevskiy, ... PLoS genetics 13 (3), e1006695, 2017 | 60 | 2017 |
| Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast C Beaupere, L Dinatto, BM Wasko, RB Chen, L VanValkenburg, ... Proceedings of the National Academy of Sciences 115 (38), 9586-9591, 2018 | 48 | 2018 |
| A novel bisphosphonate inhibitor of squalene synthase combined with a statin or a nitrogenous bisphosphonate in vitro [S] BM Wasko, JP Smits, LW Shull, DF Wiemer, RJ Hohl Journal of lipid research 52 (11), 1957-1964, 2011 | 45 | 2011 |
| Inhibition of DNA double-strand break repair by the Ku heterodimer in mrx mutants of Saccharomyces cerevisiae BM Wasko, CL Holland, MA Resnick, LK Lewis DNA repair 8 (2), 162-169, 2009 | 43 | 2009 |
| Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism R Yu, X Cao, L Sun, J Zhu, BM Wasko, W Liu, E Crutcher, H Liu, MC Jo, ... Nature Communications 12 (1), 1981, 2021 | 42 | 2021 |
| End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging JR Delaney, A Chou, B Olsen, D Carr, C Murakami, U Ahmed, S Sim, ... FEMS yeast research 13 (3), 267-276, 2013 | 37 | 2013 |
| Synthesis and biological evaluation of a series of aromatic bisphosphonates RJ Barney, BM Wasko, A Dudakovic, RJ Hohl, DF Wiemer Bioorganic & medicinal chemistry 18 (20), 7212-7220, 2010 | 34 | 2010 |
| PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae HJ Cui, XG Liu, M McCormick, BM Wasko, W Zhao, X He, Y Yuan, ... Age 37, 1-8, 2015 | 33 | 2015 |
| Buffering the pH of the culture medium does not extend yeast replicative lifespan BM Wasko, DT Carr, H Tung, H Doan, N Schurman, JR Neault, J Feng, ... F1000Research 2, 216, 2013 | 29 | 2013 |
| Yeast as a model to understand the interaction between genotype and the response to calorie restriction J Schleit, BM Wasko, M Kaeberlein FEBS letters 586 (18), 2868-2873, 2012 | 29 | 2012 |
| Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae KL Chen, TN Ven, MM Crane, MLC Brunner, AK Pun, KL Helget, K Brower, ... Geroscience 42, 749-764, 2020 | 28 | 2020 |
Raymond HohlPenn State Cancer InstituteE-mail megerősítve itt: pennstatehealth.psu.edu