Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction K Sato, A Suematsu, K Okamoto, A Yamaguchi, Y Morishita, Y Kadono, ... Journal of experimental medicine 203 (12), 2673-2682, 2006 | 1906 | 2006 |
Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis N Komatsu, K Okamoto, S Sawa, T Nakashima, M Oh-Hora, T Kodama, ... Nature medicine 20 (1), 62-68, 2014 | 1265 | 2014 |
Optically tunable amino-functionalized graphene quantum dots. H Tetsuka, R Asahi, A Nagoya, K Okamoto, I Tajima, R Ohta, A Okamoto Advanced Materials (Deerfield Beach, Fla.) 24 (39), 5333-5338, 2012 | 955 | 2012 |
Osteoimmunology: the conceptual framework unifying the immune and skeletal systems K Okamoto, T Nakashima, M Shinohara, T Negishi-Koga, N Komatsu, ... Physiological reviews 97 (4), 1295-1349, 2017 | 521 | 2017 |
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis M Asagiri, T Hirai, T Kunigami, S Kamano, HJ Gober, K Okamoto, ... Science 319 (5863), 624-627, 2008 | 376 | 2008 |
IL-17-producing γδ T cells enhance bone regeneration T Ono, K Okamoto, T Nakashima, T Nitta, S Hori, Y Iwakura, H Takayanagi Nature communications 7 (1), 10928, 2016 | 366 | 2016 |
Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals M Shinohara, T Koga, K Okamoto, S Sakaguchi, K Arai, H Yasuda, ... Cell 132 (5), 794-806, 2008 | 366 | 2008 |
Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression T Yamamoto, M Ebisuya, F Ashida, K Okamoto, S Yonehara, E Nishida Current Biology 16 (12), 1171-1182, 2006 | 348 | 2006 |
IκBζ regulates TH17 development by cooperating with ROR nuclear receptors K Okamoto, Y Iwai, M Oh-Hora, M Yamamoto, T Morio, K Aoki, K Ohya, ... Nature 464 (7293), 1381-1385, 2010 | 337 | 2010 |
Host defense against oral microbiota by bone-damaging T cells M Tsukasaki, N Komatsu, K Nagashima, T Nitta, W Pluemsakunthai, ... Nature communications 9 (1), 701, 2018 | 293 | 2018 |
Critical role of p38 and GATA3 in natural helper cell function J Furusawa, K Moro, Y Motomura, K Okamoto, J Zhu, H Takayanagi, ... The Journal of Immunology 191 (4), 1818-1826, 2013 | 147 | 2013 |
Autoregulation of osteocyte Sema3A orchestrates estrogen action and counteracts bone aging M Hayashi, T Nakashima, N Yoshimura, K Okamoto, S Tanaka, ... Cell Metabolism 29 (3), 627-637. e5, 2019 | 146 | 2019 |
Immune complexes regulate bone metabolism through FcRγ signalling T Negishi-Koga, HJ Gober, E Sumiya, N Komatsu, K Okamoto, S Sawa, ... Nature communications 6 (1), 6637, 2015 | 140 | 2015 |
Sepsis-induced osteoblast ablation causes immunodeficiency A Terashima, K Okamoto, T Nakashima, S Akira, K Ikuta, H Takayanagi Immunity 44 (6), 1434-1443, 2016 | 137 | 2016 |
Regulation of bone by the adaptive immune system in arthritis K Okamoto, H Takayanagi Arthritis research & therapy 13, 1-11, 2011 | 136 | 2011 |
Induction of apoptosis in the rheumatoid synovium by Fas ligand gene transfer K Okamoto, H Asahara, T Kobayashi, H Matsuno, T Hasunuma, T Kobata, ... Gene Therapy 5 (3), 331-338, 1998 | 124 | 1998 |
Sensitization of osteosarcoma cells to death receptor-mediated apoptosis by HDAC inhibitors through downregulation of cellular FLIP K Watanabe, K Okamoto, S Yonehara Cell Death & Differentiation 12 (1), 10-18, 2005 | 114 | 2005 |
Human T‐cell leukemia virus type‐I oncoprotein Tax inhibits Fas‐mediated apoptosis by inducing cellular FLIP through activation of NF‐κB K Okamoto, J Fujisawa, M Reth, S Yonehara Genes to Cells 11 (2), 177-191, 2006 | 102 | 2006 |
Stepwise cell fate decision pathways during osteoclastogenesis at single-cell resolution M Tsukasaki, NCN Huynh, K Okamoto, R Muro, A Terashima, Y Kurikawa, ... Nature metabolism 2 (12), 1382-1390, 2020 | 94 | 2020 |
Osteoimmunology K Okamoto, H Takayanagi Genetics of Bone Biology and Skeletal Disease, 261-282, 2018 | 90 | 2018 |