E-CRISP: fast CRISPR target site identification F Heigwer, G Kerr, M Boutros Nature methods 11 (2), 122-123, 2014 | 1018 | 2014 |
Techniques for clustering gene expression data G Kerr, HJ Ruskin, M Crane, P Doolan Computers in biology and medicine 38 (3), 283-293, 2008 | 335 | 2008 |
Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss H Liu, J Golji, LK Brodeur, FS Chung, JT Chen, RS deBeaumont, ... Nature medicine 25 (1), 95-102, 2019 | 307 | 2019 |
Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells O Voloshanenko, G Erdmann, TD Dubash, I Augustin, M Metzig, G Moffa, ... Nature communications 4 (1), 2610, 2013 | 284 | 2013 |
SHP2 inhibition restores sensitivity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors L Dardaei, HQ Wang, M Singh, P Fordjour, KX Shaw, S Yoda, G Kerr, ... Nature medicine 24 (4), 512-517, 2018 | 196 | 2018 |
GenomeRNAi: a database for cell-based and in vivo RNAi phenotypes, 2013 update EE Schmidt, O Pelz, S Buhlmann, G Kerr, T Horn, M Boutros Nucleic acids research 41 (D1), D1021-D1026, 2013 | 155 | 2013 |
RNA-Seq vs dual-and single-channel microarray data: sensitivity analysis for differential expression and clustering A Sîrbu, G Kerr, M Crane, HJ Ruskin PloS one 7 (12), e50986, 2012 | 132 | 2012 |
The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis I Augustin, V Goidts, A Bongers, G Kerr, G Vollert, B Radlwimmer, ... EMBO molecular medicine 4 (1), 38-51, 2012 | 105 | 2012 |
RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAFV600E metastatic colorectal cancer E Elez, J Ros, J Fernández, G Villacampa, AB Moreno-Cárdenas, ... Nature medicine 28 (10), 2162-2170, 2022 | 91 | 2022 |
Dose and schedule determine distinct molecular mechanisms underlying the efficacy of the p53–MDM2 inhibitor HDM201 S Jeay, S Ferretti, P Holzer, J Fuchs, EA Chapeau, M Wartmann, ... Cancer research 78 (21), 6257-6267, 2018 | 84 | 2018 |
E-TALEN: a web tool to design TALENs for genome engineering F Heigwer, G Kerr, N Walther, K Glaeser, O Pelz, M Breinig, M Boutros Nucleic acids research 41 (20), e190-e190, 2013 | 84 | 2013 |
Dpp/Gbb signaling is required for normal intestinal regeneration during infection J Zhou, S Florescu, AL Boettcher, L Luo, D Dutta, G Kerr, Y Cai, BA Edgar, ... Developmental biology 399 (2), 189-203, 2015 | 72 | 2015 |
Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis I Augustin, J Gross, D Baumann, C Korn, G Kerr, T Grigoryan, C Mauch, ... Journal of Experimental Medicine 210 (9), 1761-1777, 2013 | 55 | 2013 |
Amplicon sequencing of colorectal cancer: variant calling in frozen and formalin-fixed samples J Betge, G Kerr, T Miersch, S Leible, G Erdmann, CL Galata, T Zhan, ... PLoS One 10 (5), e0127146, 2015 | 39 | 2015 |
Comparison of microarray preprocessing methods K Shakya, HJ Ruskin, G Kerr, M Crane, J Becker Advances in computational biology, 139-147, 2010 | 36 | 2010 |
Structure of the MRAS–SHOC2–PP1C phosphatase complex ZJ Hauseman, M Fodor, A Dhembi, J Viscomi, D Egli, M Bleu, S Katz, ... Nature 609 (7926), 416-423, 2022 | 35 | 2022 |
Degron mediated BRM/SMARCA2 depletion uncovers novel combination partners for treatment of BRG1/SMARCA4-mutant cancers F Rago, MT DiMare, GN Elliott, DA Ruddy, S Sovath, G Kerr, CB Hyo-eun, ... Biochemical and biophysical research communications 508 (1), 109-116, 2019 | 35 | 2019 |
Autocrine Wnt regulates the survival and genomic stability of embryonic stem cells I Augustin, DL Dewi, J Hundshammer, G Erdmann, G Kerr, M Boutros Science signaling 10 (461), eaah6829, 2017 | 33 | 2017 |
Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers S Ferretti, J Hamon, R de Kanter, C Scheufler, R Andraos-Rey, S Barbe, ... Nature 629 (8011), 443-449, 2024 | 31 | 2024 |
Identification of the HECT E3 ligase UBR5 as a regulator of MYC degradation using a CRISPR/Cas9 screen L Schukur, T Zimmermann, O Niewoehner, G Kerr, S Gleim, ... Scientific Reports 10 (1), 20044, 2020 | 29 | 2020 |