Cikkek nyilvánosan hozzáférhető megbízással - Gary MiramsTovábbi információ
Valahol hozzáférhető: 83
Chaste: a test-driven approach to software development for biological modelling
J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ...
Computer Physics Communications 180 (12), 2452-2471, 2009
Megbízások: US National Institutes of Health
An integrative computational model for intestinal tissue renewal
IMM Van Leeuwen, GR Mirams, A Walter, A Fletcher, P Murray, J Osborne, ...
Cell proliferation 42 (5), 617-636, 2009
Megbízások: US National Institutes of Health, Cancer Research UK
Uncertainty and variability in models of the cardiac action potential: Can we build trustworthy models?
RH Johnstone, ETY Chang, R Bardenet, TP De Boer, DJ Gavaghan, ...
Journal of molecular and cellular cardiology 96, 49-62, 2016
Megbízások: UK Engineering and Physical Sciences Research Council, National Centre for …
Uncertainty and variability in computational and mathematical models of cardiac physiology
GR Mirams, P Pathmanathan, RA Gray, P Challenor, RH Clayton
The Journal of physiology 594 (23), 6833-6847, 2016
Megbízások: US National Institutes of Health, UK Engineering and Physical Sciences …
Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current I f: Novel electrophysiological insights and therapeutic potential
RA Capel, N Herring, M Kalla, A Yavari, GR Mirams, G Douglas, G Bub, ...
Heart Rhythm 12 (10), 2186-2194, 2015
Megbízások: British Heart Foundation, UK Engineering and Physical Sciences Research …
Assessment of an in silico mechanistic model for proarrhythmia risk prediction under the CiPA initiative
Z Li, WW Wu, J Sheng, PN Tran, M Wu, A Ranolph, RH Johnstone, ...
Clinical Pharmacology & Therapeutics, 2018
Megbízások: US Department of Energy, UK Engineering and Physical Sciences Research …
Application of cardiac electrophysiology simulations to pro‐arrhythmic safety testing
GR Mirams, MR Davies, Y Cui, P Kohl, D Noble
British Journal of Pharmacology 167 (5), 932-945, 2012
Megbízások: British Heart Foundation
Systems Toxicology: Real World Applications and Opportunities
T Hartung, RE FitzGerald, P Jennings, GR Mirams, MC Peitsch, ...
Chemical Research in Toxicology 30 (4), 870, 2017
Megbízások: Swiss National Science Foundation, US National Institutes of Health …
Calibration of ionic and cellular cardiac electrophysiology models
DG Whittaker, M Clerx, CL Lei, DJ Christini, GR Mirams
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 12 (4), e1482, 2020
Megbízások: US National Institutes of Health, UK Biotechnology and Biological Sciences …
Prediction of Thorough QT study results using action potential simulations based on ion channel screens
GR Mirams, MR Davies, SJ Brough, MH Bridgland-Taylor, Y Cui, ...
Journal of pharmacological and toxicological methods 70 (3), 246-254, 2014
Megbízások: US National Institutes of Health, UK Engineering and Physical Sciences …
Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment
RC Elkins, MR Davies, SJ Brough, DJ Gavaghan, Y Cui, N Abi-Gerges, ...
Journal of pharmacological and toxicological methods 68 (1), 112-122, 2013
Megbízások: US National Institutes of Health, UK Engineering and Physical Sciences …
Uncertainty quantification reveals the importance of data variability and experimental design considerations for in silico proarrhythmia risk assessment
KC Chang, S Dutta, GR Mirams, KA Beattie, J Sheng, PN Tran, M Wu, ...
Frontiers in physiology 8, 917, 2017
Megbízások: US Department of Energy, Wellcome Trust
General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy
Z Li, GR Mirams, T Yoshinaga, BJ Ridder, X Han, JE Chen, ...
Clinical Pharmacology & Therapeutics 107 (1), 102-111, 2020
Megbízások: US Department of Energy, US National Institutes of Health, British Heart …
High resolution structural evidence suggests the sarcoplasmic reticulum forms microdomains with acidic stores (lysosomes) in the heart
D Aston, RA Capel, KL Ford, HC Christian, GR Mirams, EA Rog-Zielinska, ...
Scientific Reports 7, 40620, 2017
Megbízások: US National Institutes of Health, British Heart Foundation, UK Engineering …
mRNA expression levels in failing human hearts predict cellular electrophysiological remodeling: a population-based simulation study
J Walmsley, JF Rodriguez, GR Mirams, K Burrage, IR Efimov, ...
PloS one 8 (2), e56359, 2013
Megbízások: US National Institutes of Health
Recent developments in using mechanistic cardiac modelling for drug safety evaluation
MR Davies, K Wang, GR Mirams, A Caruso, D Noble, A Walz, T Lavé, ...
Drug discovery today 21 (6), 924-938, 2016
Megbízások: Wellcome Trust
Cardiac tissue slices: preparation, handling, and successful optical mapping
K Wang, P Lee, GR Mirams, P Sarathchandra, TK Borg, DJ Gavaghan, ...
American Journal of Physiology-Heart and Circulatory Physiology 308 (9 …, 2015
Megbízások: US National Institutes of Health, UK Biotechnology and Biological Sciences …
Control of NFAT Isoform Activation and NFAT-Dependent Gene Expression through Two Coincident and Spatially Segregated Intracellular Ca 2+ Signals
P Kar, GR Mirams, HC Christian, AB Parekh
Molecular Cell 64 (4), 746-759, 2016
Megbízások: UK Engineering and Physical Sciences Research Council, UK Medical Research …
Chaste: cancer, heart and soft tissue environment
FR Cooper, RE Baker, MO Bernabeu, R Bordas, L Bowler, ...
Journal of Open Source Software, 2020
Megbízások: UK Biotechnology and Biological Sciences Research Council, British Heart …
Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing
TA Quinn, S Granite, MA Allessie, C Antzelevitch, C Bollensdorff, G Bub, ...
Progress in biophysics and molecular biology 107 (1), 4-10, 2011
Megbízások: US National Institutes of Health, British Heart Foundation
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