Cellular and molecular pathobiology of pulmonary arterial hypertension M Humbert, NW Morrell, SL Archer, KR Stenmark, MR MacLean, IM Lang, ... Journal of the American College of Cardiology 43 (12S), S13-S24, 2004 | 2179 | 2004 |
Genomic atlas of the human plasma proteome BB Sun, JC Maranville, JE Peters, D Stacey, JR Staley, J Blackshaw, ... Nature 558 (7708), 73-79, 2018 | 1779 | 2018 |
Cellular and molecular basis of pulmonary arterial hypertension NW Morrell, S Adnot, SL Archer, J Dupuis, P Lloyd Jones, MR MacLean, ... Journal of the American College of Cardiology 54 (1_Supplement_S), S20-S31, 2009 | 1082 | 2009 |
Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia RC Trembath, JR Thomson, RD Machado, NV Morgan, C Atkinson, ... New England Journal of Medicine 345 (5), 325-334, 2001 | 918 | 2001 |
Elevated levels of inflammatory cytokines predict survival in idiopathic and familial pulmonary arterial hypertension E Soon, AM Holmes, CM Treacy, NJ Doughty, L Southgate, RD Machado, ... Circulation 122 (9), 920-927, 2010 | 875 | 2010 |
Inflammation, growth factors, and pulmonary vascular remodeling PM Hassoun, L Mouthon, JA Barberà, S Eddahibi, SC Flores, ... Journal of the american college of cardiology 54 (1_Supplement_S), S10-S19, 2009 | 868 | 2009 |
Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor C Atkinson, S Stewart, PD Upton, R Machado, JR Thomson, RC Trembath, ... Circulation 105 (14), 1672-1678, 2002 | 816 | 2002 |
Relevant issues in the pathology and pathobiology of pulmonary hypertension RM Tuder, SL Archer, P Dorfmüller, SC Erzurum, C Guignabert, ... Journal of the American College of Cardiology 62 (25S), D4-D12, 2013 | 682 | 2013 |
Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study MM Hoeper, RJ Barst, RC Bourge, J Feldman, AE Frost, N Galié, ... Circulation 127 (10), 1128-1138, 2013 | 662 | 2013 |
Sildenafil inhibits hypoxia-induced pulmonary hypertension L Zhao, NA Mason, NW Morrell, B Kojonazarov, A Sadykov, A Maripov, ... Circulation 104 (4), 424-428, 2001 | 644 | 2001 |
Altered Growth Responses of Pulmonary Artery Smooth Muscle Cells From Patients With Primary Pulmonary Hypertension to Transforming Growth Factor-β1 and … NW Morrell, X Yang, PD Upton, KB Jourdan, N Morgan, KK Sheares, ... Circulation 104 (7), 790-795, 2001 | 587 | 2001 |
Mutations of the TGF‐β type II receptor BMPR2 in pulmonary arterial hypertension RD Machado, MA Aldred, V James, RE Harrison, B Patel, EC Schwalbe, ... Human mutation 27 (2), 121-132, 2006 | 544 | 2006 |
Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension L Long, ML Ormiston, X Yang, M Southwood, S Gräf, RD Machado, ... Nature medicine 21 (7), 777-785, 2015 | 522 | 2015 |
Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension TK Jeffery, NW Morrell Progress in cardiovascular diseases 45 (3), 173-202, 2002 | 516 | 2002 |
Whole-genome sequencing of patients with rare diseases in a national health system E Turro, WJ Astle, K Megy, S Gräf, D Greene, O Shamardina, HL Allen, ... Nature 583 (7814), 96-102, 2020 | 506 | 2020 |
Genetics and genomics of pulmonary arterial hypertension NW Morrell, MA Aldred, WK Chung, CG Elliott, WC Nichols, F Soubrier, ... European Respiratory Journal 53 (1), 2019 | 480 | 2019 |
Imatinib in pulmonary arterial hypertension patients with inadequate response to established therapy HA Ghofrani, NW Morrell, MM Hoeper, H Olschewski, AJ Peacock, ... American journal of respiratory and critical care medicine 182 (9), 1171-1177, 2010 | 475 | 2010 |
Comprehensive rare variant analysis via whole-genome sequencing to determine the molecular pathology of inherited retinal disease KJ Carss, G Arno, M Erwood, J Stephens, A Sanchis-Juan, S Hull, K Megy, ... The American Journal of Human Genetics 100 (1), 75-90, 2017 | 466 | 2017 |
ETA and ETB receptors modulate the proliferation of human pulmonary artery smooth muscle cells N Davie, SJ Haleen, PD Upton, JM Polak, MH Yacoub, NW Morrell, ... American journal of respiratory and critical care medicine 165 (3), 398-405, 2002 | 453 | 2002 |
Dysfunctional Smad signaling contributes to abnormal smooth muscle cell proliferation in familial pulmonary arterial hypertension X Yang, L Long, M Southwood, N Rudarakanchana, PD Upton, TK Jeffery, ... Circulation research 96 (10), 1053-1063, 2005 | 449 | 2005 |