Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells J Boren, M Cascante, S Marin, B Comın-Anduix, JJ Centelles, S Lim, ... Journal of Biological Chemistry 276 (41), 37747-37753, 2001 | 225 | 2001 |
Metabolic strategy of boar spermatozoa revealed by a metabolomic characterization S Marin, K Chiang, S Bassilian, WNP Lee, LG Boros, ... FEBS letters 554 (3), 342-346, 2003 | 180 | 2003 |
Novel semisynthetic derivatives of betulin and betulinic acid with cytotoxic activity RC Santos, JAR Salvador, S Marín, M Cascante Bioorganic & medicinal chemistry 17 (17), 6241-6250, 2009 | 175 | 2009 |
COordination of Standards in MetabOlomicS (COSMOS): facilitating integrated metabolomics data access RM Salek, S Neumann, D Schober, J Hummel, K Billiau, J Kopka, ... Metabolomics 11, 1587-1597, 2015 | 173 | 2015 |
Metabolomics and fluxomics approaches M Cascante, S Marin Essays in biochemistry 45, 67-82, 2008 | 160 | 2008 |
Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly (ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells B Comın-Anduix, LG Boros, S Marin, J Boren, C Callol-Massot, ... Journal of Biological Chemistry 277 (48), 46408-46414, 2002 | 151 | 2002 |
Metabolic reprogramming and dependencies associated with epithelial cancer stem cells independent of the epithelial-mesenchymal transition program E Aguilar, I Marin de Mas, E Zodda, S Marin, F Morrish, V Selivanov, ... Stem cells 34 (5), 1163-1176, 2016 | 101 | 2016 |
Wheat germ extract decreases glucose uptake and RNA ribose formation but increases fatty acid synthesis in MIA pancreatic adenocarcinoma cells LG Boros, K Lapis, B Szende, R Tömösközi-Farkas, Á Balogh, J Boren, ... Pancreas 23 (2), 141-147, 2001 | 97 | 2001 |
Relevance of the MEK/ERK signaling pathway in the metabolism of activated macrophages: a metabolomic approach PG Través, P de Atauri, S Marín, M Pimentel-Santillana, ... The Journal of immunology 188 (3), 1402-1410, 2012 | 95 | 2012 |
Synthesis and structure–activity relationship study of novel cytotoxic carbamate and N-acylheterocyclic bearing derivatives of betulin and betulinic acid RC Santos, JAR Salvador, S Marín, M Cascante, JN Moreira, TCP Dinis Bioorganic & medicinal chemistry 18 (12), 4385-4396, 2010 | 90 | 2010 |
Glucose-6-phosphate dehydrogenase and transketolase modulate breast cancer cell metabolic reprogramming and correlate with poor patient outcome A Benito, IH Polat, V Noé, CJ Ciudad, S Marin, M Cascante Oncotarget 8 (63), 106693, 2017 | 67 | 2017 |
A key role for transketolase-like 1 in tumor metabolic reprogramming S Diaz-Moralli, E Aguilar, S Marin, JF Coy, M Dewerchin, MR Antoniewicz, ... Oncotarget 7 (32), 51875, 2016 | 67 | 2016 |
Dynamic profiling of the glucose metabolic network in fasted rat hepatocytes using [1,2-13C2]glucose S Marin, WNP LEE, S Bassilian, S Lim, LG Boros, JJ Centelles, ... Biochemical Journal 381 (1), 287-294, 2004 | 67 | 2004 |
New betulinic acid derivatives induce potent and selective antiproliferative activity through cell cycle arrest at the S phase and caspase dependent apoptosis in human cancer cells RC Santos, JAR Salvador, R Cortés, G Pachón, S Marín, M Cascante Biochimie 93 (6), 1065-1075, 2011 | 61 | 2011 |
Synthesis and anticancer activity of novel fluorinated asiatic acid derivatives BMF Goncalves, JAR Salvador, S Marin, M Cascante European Journal of Medicinal Chemistry 114, 101-117, 2016 | 59 | 2016 |
The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia A Erdem, S Marin, DA Pereira-Martins, R Cortés, A Cunningham, ... Nature Communications 13 (1), 1105, 2022 | 47 | 2022 |
Software for dynamic analysis of tracer-based metabolomic data: estimation of metabolic fluxes and their statistical analysis VA Selivanov, S Marin, PWN Lee, M Cascante Bioinformatics 22 (22), 2806-2812, 2006 | 46 | 2006 |
Model-driven discovery of long-chain fatty acid metabolic reprogramming in heterogeneous prostate cancer cells I Marin de Mas, E Aguilar, E Zodda, C Balcells, S Marin, G Dallmann, ... PLOS Computational Biology 14 (1), e1005914, 2018 | 44 | 2018 |
Epicatechin gallate impairs colon cancer cell metabolic productivity S Sanchez-Tena, G Alcarraz-Vizan, S Marin, JL Torres, M Cascante Journal of agricultural and food chemistry 61 (18), 4310-4317, 2013 | 40 | 2013 |
Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability A Erdem, S Marin, DA Pereira-Martins, M Geugien, A Cunningham, ... Nature Communications 13 (1), 2013, 2022 | 36 | 2022 |