Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues X Zhang, DT Odom, SH Koo, MD Conkright, G Canettieri, J Best, H Chen, ... Proceedings of the National Academy of Sciences 102 (12), 4459-4464, 2005 | 1179 | 2005 |
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B G Rena, S Guo, SC Cichy, TG Unterman, P Cohen Journal of Biological Chemistry 274 (24), 17179-17183, 1999 | 962 | 1999 |
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis V Nogueira, Y Park, CC Chen, PZ Xu, ML Chen, I Tonic, T Unterman, ... Cancer cell 14 (6), 458-470, 2008 | 892 | 2008 |
FoxO proteins in insulin action and metabolism A Barthel, D Schmoll, TG Unterman Trends in Endocrinology & Metabolism 16 (4), 183-189, 2005 | 753 | 2005 |
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter … S Guo, G Rena, S Cichy, X He, P Cohen, T Unterman Journal of Biological Chemistry 274 (24), 17184-17192, 1999 | 700 | 1999 |
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression W Zhang, S Patil, B Chauhan, S Guo, DR Powell, J Le, A Klotsas, ... Journal of Biological Chemistry 281 (15), 10105-10117, 2006 | 644 | 2006 |
Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings AR Barnosky, KK Hoddy, TG Unterman, KA Varady Translational Research 164 (4), 302-311, 2014 | 492 | 2014 |
Regulation of glucose-6-phosphatase gene expression by protein kinase Bα and the Forkhead transcription factor FKHR: evidence for insulin response unit-dependent and … D Schmoll, KS Walker, DR Alessi, R Grempler, A Burchell, S Guo, ... Journal of Biological Chemistry 275 (46), 36324-36333, 2000 | 443 | 2000 |
Hepatic insulin resistance directly promotes formation of cholesterol gallstones SB Biddinger, JT Haas, BB Yu, O Bezy, E Jing, W Zhang, TG Unterman, ... Nature medicine 14 (7), 778-782, 2008 | 438 | 2008 |
Phosphorylation of serine 256 suppresses transactivation by FKHR (FOXO1) by multiple mechanisms: direct and indirect effects on nuclear/cytoplasmic shuttling and DNA binding X Zhang, L Gan, H Pan, S Guo, X He, ST Olson, A Mesecar, S Adam, ... Journal of Biological Chemistry 277 (47), 45276-45284, 2002 | 380 | 2002 |
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration Z Sun, RA Miller, RT Patel, J Chen, R Dhir, H Wang, D Zhang, MJ Graham, ... Nature medicine 18 (6), 934-942, 2012 | 360 | 2012 |
Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors DL Allen, TG Unterman American Journal of Physiology-Cell Physiology 292 (1), C188-C199, 2007 | 348 | 2007 |
Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting G Rena, AR Prescott, S Guo, P Cohen, TG Unterman Biochemical Journal 354 (3), 605-612, 2001 | 339 | 2001 |
The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site YL Woods, G Rena, N Morrice, A Barthel, W Becker, S Guo, TG Unterman, ... Biochemical Journal 355 (3), 597-607, 2001 | 331 | 2001 |
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion G Rena, YL Woods, AR Prescott, M Peggie, TG Unterman, MR Williams, ... The EMBO journal, 2002 | 304 | 2002 |
Multiple elements regulate nuclear/cytoplasmic shuttling of FOXO1: characterization of phosphorylation-and 14-3-3-dependent and-independent mechanisms X Zhao, L Gan, H Pan, D Kan, M Majeski, SA Adam, TG Unterman Biochemical Journal 378 (3), 839-849, 2004 | 286 | 2004 |
Transcriptional cross talk between the forkhead transcription factor forkhead box O1A and the progesterone receptor coordinates cell cycle regulation and differentiation in … M Takano, Z Lu, T Goto, L Fusi, J Higham, J Francis, A Withey, J Hardt, ... Molecular endocrinology 21 (10), 2334-2349, 2007 | 246 | 2007 |
Serum levels of total and free IGF-I and IGFBP-3 are increased and maintained in long-term training LP Koziris, RC Hickson, RT Chatterton Jr, RT Groseth, JM Christie, ... Journal of applied physiology 86 (4), 1436-1442, 1999 | 233 | 1999 |
Induction of cyclin D2 in rat granulosa cells requires FSH-dependent relief from FOXO1 repression coupled with positive signals from Smad Y Park, ET Maizels, ZJ Feiger, H Alam, CA Peters, TK Woodruff, ... Journal of Biological Chemistry 280 (10), 9135-9148, 2005 | 226 | 2005 |
Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein β in differentiating human endometrial stromal cells M Christian, X Zhang, T Schneider-Merck, TG Unterman, B Gellersen, ... Journal of Biological Chemistry 277 (23), 20825-20832, 2002 | 226 | 2002 |