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Lachlan Whitehead
Lachlan Whitehead
Adresse e-mail validée de wehi.edu.au
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BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis
K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ...
Science 359 (6378), eaao6047, 2018
7802018
Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G Núñez, ...
Proceedings of the National Academy of Sciences 114 (6), E961-E969, 2017
4322017
RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers
E Nolan, F Vaillant, D Branstetter, B Pal, G Giner, L Whitehead, SW Lok, ...
Nature medicine 22 (8), 933-939, 2016
2842016
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ...
Nature communications 11 (1), 3151, 2020
2612020
Essential role of the PfRh5/PfRipr/CyRPA complex during Plasmodium falciparum invasion of erythrocytes
JC Volz, A Yap, X Sisquella, JK Thompson, NTY Lim, LW Whitehead, ...
Cell host & microbe 20 (1), 60-71, 2016
2512016
Embryogenesis and adult life in the absence of intrinsic apoptosis effectors BAX, BAK, and BOK
FFS Ke, HK Vanyai, AD Cowan, ARD Delbridge, L Whitehead, S Grabow, ...
Cell 173 (5), 1217-1230. e17, 2018
2022018
Diffractive imaging using partially coherent x rays
LW Whitehead, GJ Williams, HM Quiney, DJ Vine, RA Dilanian, S Flewett, ...
Physical review letters 103 (24), 243902, 2009
1872009
The neuropeptide VIP confers anticipatory mucosal immunity by regulating ILC3 activity
C Seillet, K Luong, J Tellier, N Jacquelot, RD Shen, P Hickey, VC Wimmer, ...
Nature immunology 21 (2), 168-177, 2020
1722020
Lensless imaging using broadband X-ray sources
B Abbey, LW Whitehead, HM Quiney, DJ Vine, GA Cadenazzi, ...
Nature Photonics 5 (7), 420-424, 2011
1722011
IL-18 production from the NLRP1 inflammasome prevents obesity and metabolic syndrome
AJ Murphy, MJ Kraakman, HL Kammoun, D Dragoljevic, MKS Lee, ...
Cell metabolism 23 (1), 155-164, 2016
1692016
TgCDPK3 Regulates Calcium-Dependent Egress of Toxoplasma gondii from Host Cells
JM McCoy, L Whitehead, GG van Dooren, CJ Tonkin
PLoS Pathogens 8 (12), e1003066, 2012
1612012
Intraclonal plasticity in mammary tumors revealed through large-scale single-cell resolution 3D imaging
AC Rios, BD Capaldo, F Vaillant, B Pal, R van Ineveld, CA Dawson, ...
Cancer cell 35 (4), 618-632. e6, 2019
1562019
Inhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasites
BE Sleebs, S Lopaticki, DS Marapana, MT O'Neill, P Rajasekaran, ...
PLoS biology 12 (7), e1001897, 2014
1552014
SIDT2 transports extracellular dsRNA into the cytoplasm for innate immune recognition
TA Nguyen, BRC Smith, MD Tate, GT Belz, MH Barrios, KD Elgass, ...
Immunity 47 (3), 498-509. e6, 2017
1372017
Essential role for a novel population of binucleated mammary epithelial cells in lactation
AC Rios, NY Fu, PR Jamieson, B Pal, L Whitehead, KR Nicholas, ...
Nature communications 7 (1), 11400, 2016
1002016
DaXi—high-resolution, large imaging volume and multi-view single-objective light-sheet microscopy
B Yang, M Lange, A Millett-Sikking, X Zhao, J Bragantini, S VijayKumar, ...
Nature methods 19 (4), 461-469, 2022
982022
Monosodium urate crystals generate nuclease-resistant neutrophil extracellular traps via a distinct molecular pathway
SM Chatfield, K Grebe, LW Whitehead, KL Rogers, T Nebl, JM Murphy, ...
The Journal of Immunology 200 (5), 1802-1816, 2018
922018
A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo
KS Potts, TJ Sargeant, JF Markham, W Shi, C Biben, EC Josefsson, ...
Blood, The Journal of the American Society of Hematology 124 (17), 2725-2729, 2014
822014
Plasmodium falciparum ligand binding to erythrocytes induce alterations in deformability essential for invasion
X Sisquella, T Nebl, JK Thompson, L Whitehead, BM Malpede, ...
Elife 6, e21083, 2017
772017
Inhibition of hematopoietic cell kinase activity suppresses myeloid cell-mediated colon cancer progression
AR Poh, CG Love, F Masson, A Preaudet, C Tsui, L Whitehead, S Monard, ...
Cancer Cell 31 (4), 563-575. e5, 2017
702017
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