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Donald Gray Heppner
Donald Gray Heppner
Quigley BioPharma LLC
Adresse e-mail validée de quigleybio.com
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A Preliminary Evaluation of a Recombinant Circumsporozoite Protein Vaccine against Plasmodium falciparum Malaria
JA Stoute, M Slaoui, DG Heppner, P Momin, KE Kester, P Desmons, ...
New England Journal of Medicine 336 (2), 86-91, 1997
11211997
Protection of Humans against Malaria by Immunization with Radiation-Attenuated Plasmodium falciparum Sporozoites
SL Hoffman, LML Goh, TC Luke, I Schneider, TP Le, DL Doolan, J Sacci, ...
The Journal of infectious diseases 185 (8), 1155-1164, 2002
10102002
Enhanced T-cell immunogenicity of plasmid DNA vaccines boosted by recombinant modified vaccinia virus Ankara in humans
SJ McConkey, WHH Reece, VS Moorthy, D Webster, S Dunachie, ...
Nature medicine 9 (6), 729-735, 2003
7232003
Randomized, double-blind, phase 2a trial of falciparum malaria vaccines RTS, S/AS01B and RTS, S/AS02A in malaria-naive adults: safety, efficacy, and immunologic associates of …
KE Kester, JF Cummings, O Ofori-Anyinam, CF Ockenhouse, U Krzych, ...
Journal of Infectious Diseases 200 (3), 337-346, 2009
614*2009
A Recombinant Vesicular Stomatitis Virus Ebola Vaccine.
JA Regules, B JH
N Engl J Med 376 (4), 330-341, 2017
4622017
A field trial to assess a blood-stage malaria vaccine
MA Thera, OK Doumbo, D Coulibaly, MB Laurens, A Ouattara, AK Kone, ...
New England Journal of Medicine 365 (11), 1004-1013, 2011
4542011
Safety, Immunogenicity, and Efficacy of a Recombinantly Produced Plasmodium falciparum Circumsporozoite Protein-Hepatitis B Surface Antigen Subunit Vaccine
DM Gordon, TW McGovern, U Krzych, JC Cohen, I Schneider, ...
Journal of Infectious Diseases 171 (6), 1576-1585, 1995
4301995
Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya
BR Ogutu, OJ Apollo, D McKinney, W Okoth, J Siangla, F Dubovsky, ...
PloS one 4 (3), e4708, 2009
3872009
Efficacy of Recombinant Circumsporozoite Protein Vaccine Regimens against Experimental Plasmodium falciparum Malaria
KE Kester, DA McKinney, N Tornieporth, CF Ockenhouse, DG Heppner, ...
The Journal of infectious diseases 183 (4), 640-647, 2001
3612001
Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway
S Pichyangkul, K Yongvanitchit, U Kum-Arb, H Hemmi, S Akira, AM Krieg, ...
The Journal of Immunology 172 (8), 4926-4933, 2004
3522004
Protective immunity induced with malaria vaccine, RTS, S, is linked to Plasmodium falciparum circumsporozoite protein-specific CD4+ and CD8+ T cells producing IFN-γ
P Sun, R Schwenk, K White, JA Stoute, J Cohen, WR Ballou, G Voss, ...
The Journal of Immunology 171 (12), 6961-6967, 2003
3042003
Towards an RTS, S-based, multi-stage, multi-antigen vaccine against falciparum malaria: progress at the Walter Reed Army Institute of Research
DG Heppner Jr, KE Kester, CF Ockenhouse, N Tornieporth, O Ofori, ...
Vaccine 23 (17-18), 2243-2250, 2005
2582005
Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A
MD Spring, JF Cummings, CF Ockenhouse, S Dutta, R Reidler, E Angov, ...
PloS one 4 (4), e5254, 2009
2462009
Plasmodium falciparum antimalarial drug susceptibility on the north-western border of Thailand during five years of extensive use of artesunate-mefloquine
A Brockman, RN Price, M Van Vugt, DG Heppner, D Walsh, P Sookto, ...
Transactions of the Royal Society of Tropical Medicine and Hygiene 94 (5 …, 2000
2422000
Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand
F Nosten, C Luxemburger, DE Kyle, WR Ballou, J Wittes, EH Wah, ...
The lancet 348 (9029), 701-707, 1996
2381996
Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design
KM VanBuskirk, MT O'Neill, P De La Vega, AG Maier, U Krzych, J Williams, ...
Proceedings of the National Academy of Sciences 106 (31), 13004-13009, 2009
2112009
Update on the clinical development of candidate malaria vaccines
WR Ballou, M Arevalo-Herrera, D Carucci, TL Richie, G Corradin, C Diggs, ...
The Intolerable Burden of Malaria II: What's New, What's Needed: Supplement …, 2004
2052004
Safety and immunogenicity of single-dose live oral cholera vaccine CVD 103-HgR in 5-9-year-old Indonesian children
C Simanjuntak, H Totosudirjo, N Witham, N Punjabi, D Burr, K Sorenson, ...
The Lancet 340 (8821), 689-694, 1992
1891992
First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers
M Spring, J Murphy, R Nielsen, M Dowler, JW Bennett, S Zarling, ...
Vaccine 31 (43), 4975-4983, 2013
1812013
Salmonella typhi Vaccine Strain CVD 908 Expressing the Circumsporozoite Protein of Plasmodium falciparum: Strain Construction and Safety and Immunogenicity …
C Gonzalez, D Hone, FR Noriega, CO Tacket, JR Davis, G Losonsky, ...
Journal of Infectious Diseases 169 (4), 927-931, 1994
1811994
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