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James W. Ajioka
James W. Ajioka
Cambridge
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Polymorphic secreted kinases are key virulence factors in toxoplasmosis
JPJ Saeij, JP Boyle, S Coller, S Taylor, LD Sibley, ET Brooke-Powell, ...
Science 314 (5806), 1780-1783, 2006
6852006
Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages
C Su, A Khan, P Zhou, D Majumdar, D Ajzenberg, ML Dardé, XQ Zhu, ...
Proceedings of the National Academy of Sciences 109 (15), 5844-5849, 2012
4682012
Recent expansion of Toxoplasma through enhanced oral transmission
C Su, D Evans, RH Cole, JC Kissinger, JW Ajioka, LD Sibley
Science 299 (5605), 414-416, 2003
4532003
Genetic analyses of atypical Toxoplasma gondii strains reveal a fourth clonal lineage in North America
A Khan, JP Dubey, C Su, JW Ajioka, BM Rosenthal, LD Sibley
International journal for parasitology 41 (6), 645-655, 2011
3942011
Population Structure of Toxoplasma gondii: Clonal Expansion Driven by Infrequent Recombination and Selective Sweeps
LD Sibley, JW Ajioka
Annu. Rev. Microbiol. 62 (1), 329-351, 2008
3262008
Genetic diversity of Toxoplasma gondii in animals and humans
LD Sibley, A Khan, JW Ajioka, BM Rosenthal
Philosophical Transactions of the Royal Society B: Biological Sciences 364 …, 2009
3182009
Lack of polymorphism on the Drosophila fourth chromosome resulting from selection.
AJ Berry, JW Ajioka, M Kreitman
Genetics 129 (4), 1111-1117, 1991
3181991
Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes
H Lorenzi, A Khan, MS Behnke, S Namasivayam, LS Swapna, ...
Nature communications 7 (1), 10147, 2016
2842016
Recent transcontinental sweep of Toxoplasma gondii driven by a single monomorphic chromosome
A Khan, B Fux, C Su, JP Dubey, ML Dardé, JW Ajioka, BM Rosenthal, ...
Proceedings of the National Academy of Sciences 104 (37), 14872-14877, 2007
2572007
Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent …
G Hermes, JW Ajioka, KA Kelly, E Mui, F Roberts, K Kasza, T Mayr, ...
Journal of neuroinflammation 5, 1-37, 2008
2552008
Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii
A Khan, S Taylor, C Su, AJ Mackey, J Boyle, R Cole, D Glover, K Tang, ...
Nucleic acids research 33 (9), 2980-2992, 2005
2502005
Identification of quantitative trait loci controlling acute virulence in Toxoplasma gondii
C Su, DK Howe, JP Dubey, JW Ajioka, LD Sibley
Proceedings of the National Academy of Sciences 99 (16), 10753-10758, 2002
2342002
A family of transmembrane microneme proteins of Toxoplasma gondii contain EGF-like domains and function as escorters
M Meissner, M Reiss, N Viebig, VB Carruthers, C Toursel, S Tomavo, ...
Journal of cell science 115 (3), 563-574, 2002
2262002
Molecular characterisation of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2
KL Wan, VB Carruthers, LD Sibley, JW Ajioka
Molecular and biochemical parasitology 84 (2), 203-214, 1997
2261997
Gene discovery by EST sequencing in Toxoplasma gondiireveals sequences restricted to the apicomplexa
JW Ajioka, JC Boothroyd, BP Brunk, A Hehl, L Hillier, ID Manger, M Marra, ...
Genome research 8 (1), 18-28, 1998
2191998
Mapping the Drosophila genome with yeast artificial chromosomes
D Garza, JW Ajioka, DT Burke, DL Hartl
Science 246 (4930), 641-646, 1989
1761989
Selection at a Single Locus Leads to Widespread Expansion of Toxoplasma gondii Lineages That Are Virulent in Mice
A Khan, S Taylor, JW Ajioka, BM Rosenthal, LD Sibley
PLoS Genetics 5 (3), e1000404, 2009
1682009
Just one cross appears capable of dramatically altering the population biology of a eukaryotic pathogen like Toxoplasma gondii
JP Boyle, B Rajasekar, JPJ Saeij, JW Ajioka, M Berriman, I Paulsen, ...
Proceedings of the National Academy of Sciences 103 (27), 10514-10519, 2006
1592006
The genomic organization and transcription of the ubiquitin genes of Trypanosoma cruzi.
J Swindle, J Ajioka, H Eisen, B Sanwal, C Jacquemot, Z Browder, G Buck
The EMBO Journal 7 (4), 1121-1127, 1988
1411988
Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii
M Gissot, KA Kelly, JW Ajioka, JM Greally, K Kim
PLoS pathogens 3 (6), e77, 2007
1352007
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