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Wilbur Kearse Milhous
Wilbur Kearse Milhous
Professor and Associate Dean for Research
Adresse e-mail validée de health.usf.edu
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Reversal of Chloroquine Resistance in Plasmodium falciparum by Verapamil
SK Martin, AMJ Oduola, WK Milhous
Science 235 (4791), 899-901, 1987
8111987
Efflux of Chloroquine from Plasmodium falciparum: Mechanism of Chloroquine Resistance
DJ Krogstad, IY Gluzman, DE Kyle, AMJ Oduola, SK Martin, WK Milhous, ...
Science 238 (4831), 1283-1285, 1987
7741987
Evidence for the shikimate pathway in apicomplexan parasites
F Roberts, CW Roberts, JJ Johnson, DE Kyle, T Krell, JR Coggins, ...
Nature 393 (6687), 801-805, 1998
6391998
Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria.
DS Peterson, WK Milhous, TE Wellems
Proceedings of the National Academy of Sciences 87 (8), 3018-3022, 1990
5541990
Arteether, a new antimalarial drug: synthesis and antimalarial properties
A Brossi, B Venugopalan, L Dominguez Gerpe, HJC Yeh, ...
Journal of medicinal chemistry 31 (3), 645-650, 1988
4451988
Isolation of artemisinin (qinghaosu) from Artemisia annua growing in the United States
DL Klayman, AJ Lin, N Acton, JP Scovill, JM Hoch, WK Milhous, ...
Journal of natural products 47 (4), 715-717, 1984
3991984
Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand
CM Wilson, SK Volkman, S Thaithong, RK Martin, DE Kyle, WK Milhous, ...
Molecular and biochemical parasitology 57 (1), 151-160, 1993
3591993
Reversal of Chloroquine Resistance in Malaria Parasite Plasmodium falciparum by Desipramine
AJ Bitonti, A Sjoerdsma, PP McCann, DE Kyle, AMJ Oduola, RN Rossan, ...
Science 242 (4883), 1301-1303, 1988
3131988
Antimalarial activity of new water-soluble dihydroartemisinin derivatives
AJ Lin, DL Klayman, WK Milhous
Journal of medicinal chemistry 30 (11), 2147-2150, 1987
3111987
In vitro activities of and mechanisms of resistance to antifol antimalarial drugs
WK Milhous, NF Weatherly, JH Bowdre, RE Desjardins
Antimicrobial agents and chemotherapy 27 (4), 525-530, 1985
2771985
Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered …
GH Posner, CH Oh, D Wang, L Gerena, WK Milhous, SR Meshnick, ...
Journal of medicinal chemistry 37 (9), 1256-1258, 1994
2581994
Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I
R McLeod, SP Muench, JB Rafferty, DE Kyle, EJ Mui, MJ Kirisits, DG Mack, ...
International journal for parasitology 31 (2), 109-113, 2001
2552001
The shikimate pathway and its branches in apicomplexan parasites
CW Roberts, F Roberts, RE Lyons, MJ Kirisits, EJ Mui, J Finnerty, ...
The Journal of infectious diseases 185 (Supplement_1), S25-S36, 2002
2462002
Dispiro-1, 2, 4, 5-tetraoxanes: a new class of antimalarial peroxides
JL Vennerstrom, HN Fu, WY Ellis, AL Ager Jr, JK Wood, SL Andersen, ...
Journal of medicinal chemistry 35 (16), 3023-3027, 1992
2361992
Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance.
MG Zalis, L Pang, MS Silveira, WK Milhous, DF Wirth
The American journal of tropical medicine and hygiene 58 (5), 630-637, 1998
1881998
Plasmodium falciparum: induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro
AMJ Oduola, WK Milhous, NF Weatherly, JH Bowdre, RE Desjardins
Experimental parasitology 67 (2), 354-360, 1988
1861988
Plasmodium falciparum crossresistance between trimethoprim and pyrimethamine
JK Iyer, WK Milhous, JF Cortese, JG Kublin, CV Plowe
The Lancet 358 (9287), 1066-1067, 2001
1812001
Assessment of Azithromycin in Combination with Other Antimalarial Drugs against Plasmodium falciparum In Vitro
C Ohrt, GD Willingmyre, P Lee, C Knirsch, W Milhous
Antimicrobial agents and chemotherapy 46 (8), 2518-2524, 2002
1802002
Structure-activity relationship study of antimalarial indolo [2, 1-b] quinazoline-6, 12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of …
AK Bhattacharjee, MG Hartell, DA Nichols, RP Hicks, B Stanton, ...
European journal of medicinal chemistry 39 (1), 59-67, 2004
1722004
Bisquinolines. 1. N, N-bis (7-chloroquinolin-4-yl) alkanediamines with potential against chloroquine-resistant malaria
JL Vennerstrom, WY Ellis, AL Ager Jr, SL Andersen, L Gerena, ...
Journal of medicinal chemistry 35 (11), 2129-2134, 1992
1721992
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