Reversal of Chloroquine Resistance in Plasmodium falciparum by Verapamil SK Martin, AMJ Oduola, WK Milhous Science 235 (4791), 899-901, 1987 | 811 | 1987 |
Efflux of Chloroquine from Plasmodium falciparum: Mechanism of Chloroquine Resistance DJ Krogstad, IY Gluzman, DE Kyle, AMJ Oduola, SK Martin, WK Milhous, ... Science 238 (4831), 1283-1285, 1987 | 774 | 1987 |
Evidence for the shikimate pathway in apicomplexan parasites F Roberts, CW Roberts, JJ Johnson, DE Kyle, T Krell, JR Coggins, ... Nature 393 (6687), 801-805, 1998 | 639 | 1998 |
Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria. DS Peterson, WK Milhous, TE Wellems Proceedings of the National Academy of Sciences 87 (8), 3018-3022, 1990 | 554 | 1990 |
Arteether, a new antimalarial drug: synthesis and antimalarial properties A Brossi, B Venugopalan, L Dominguez Gerpe, HJC Yeh, ... Journal of medicinal chemistry 31 (3), 645-650, 1988 | 445 | 1988 |
Isolation of artemisinin (qinghaosu) from Artemisia annua growing in the United States DL Klayman, AJ Lin, N Acton, JP Scovill, JM Hoch, WK Milhous, ... Journal of natural products 47 (4), 715-717, 1984 | 399 | 1984 |
Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand CM Wilson, SK Volkman, S Thaithong, RK Martin, DE Kyle, WK Milhous, ... Molecular and biochemical parasitology 57 (1), 151-160, 1993 | 359 | 1993 |
Reversal of Chloroquine Resistance in Malaria Parasite Plasmodium falciparum by Desipramine AJ Bitonti, A Sjoerdsma, PP McCann, DE Kyle, AMJ Oduola, RN Rossan, ... Science 242 (4883), 1301-1303, 1988 | 313 | 1988 |
Antimalarial activity of new water-soluble dihydroartemisinin derivatives AJ Lin, DL Klayman, WK Milhous Journal of medicinal chemistry 30 (11), 2147-2150, 1987 | 311 | 1987 |
In vitro activities of and mechanisms of resistance to antifol antimalarial drugs WK Milhous, NF Weatherly, JH Bowdre, RE Desjardins Antimicrobial agents and chemotherapy 27 (4), 525-530, 1985 | 277 | 1985 |
Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered … GH Posner, CH Oh, D Wang, L Gerena, WK Milhous, SR Meshnick, ... Journal of medicinal chemistry 37 (9), 1256-1258, 1994 | 258 | 1994 |
Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I R McLeod, SP Muench, JB Rafferty, DE Kyle, EJ Mui, MJ Kirisits, DG Mack, ... International journal for parasitology 31 (2), 109-113, 2001 | 255 | 2001 |
The shikimate pathway and its branches in apicomplexan parasites CW Roberts, F Roberts, RE Lyons, MJ Kirisits, EJ Mui, J Finnerty, ... The Journal of infectious diseases 185 (Supplement_1), S25-S36, 2002 | 246 | 2002 |
Dispiro-1, 2, 4, 5-tetraoxanes: a new class of antimalarial peroxides JL Vennerstrom, HN Fu, WY Ellis, AL Ager Jr, JK Wood, SL Andersen, ... Journal of medicinal chemistry 35 (16), 3023-3027, 1992 | 236 | 1992 |
Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance. MG Zalis, L Pang, MS Silveira, WK Milhous, DF Wirth The American journal of tropical medicine and hygiene 58 (5), 630-637, 1998 | 188 | 1998 |
Plasmodium falciparum: induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro AMJ Oduola, WK Milhous, NF Weatherly, JH Bowdre, RE Desjardins Experimental parasitology 67 (2), 354-360, 1988 | 186 | 1988 |
Plasmodium falciparum crossresistance between trimethoprim and pyrimethamine JK Iyer, WK Milhous, JF Cortese, JG Kublin, CV Plowe The Lancet 358 (9287), 1066-1067, 2001 | 181 | 2001 |
Assessment of Azithromycin in Combination with Other Antimalarial Drugs against Plasmodium falciparum In Vitro C Ohrt, GD Willingmyre, P Lee, C Knirsch, W Milhous Antimicrobial agents and chemotherapy 46 (8), 2518-2524, 2002 | 180 | 2002 |
Structure-activity relationship study of antimalarial indolo [2, 1-b] quinazoline-6, 12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of … AK Bhattacharjee, MG Hartell, DA Nichols, RP Hicks, B Stanton, ... European journal of medicinal chemistry 39 (1), 59-67, 2004 | 172 | 2004 |
Bisquinolines. 1. N, N-bis (7-chloroquinolin-4-yl) alkanediamines with potential against chloroquine-resistant malaria JL Vennerstrom, WY Ellis, AL Ager Jr, SL Andersen, L Gerena, ... Journal of medicinal chemistry 35 (11), 2129-2134, 1992 | 172 | 1992 |