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| A comparative study of available software for high‐accuracy homology modeling: From sequence alignments to structural models A Nayeem, D Sitkoff, S Krystek Jr Protein Science 15 (4), 808-824, 2006 | 225 | 2006 |
| Outcome of a workshop on applications of protein models in biomedical research T Schwede, A Sali, B Honig, M Levitt, HM Berman, D Jones, SE Brenner, ... Structure 17 (2), 151-159, 2009 | 158 | 2009 |
| Pharmacological and x-ray structural characterization of a novel selective androgen receptor modulator: potent hyperanabolic stimulation of skeletal muscle with hypostimulation … J Ostrowski, JE Kuhns, JA Lupisella, MC Manfredi, BC Beehler, ... Endocrinology 148 (1), 4-12, 2007 | 154 | 2007 |
| Affinity and specificity of serine endopeptidase-protein inhibitor interactions: empirical free energy calculations based on X-ray crystallographic structures S Krystek, T Stouch, J Novotny Journal of molecular biology 234 (3), 661-679, 1993 | 146 | 1993 |
| Conformational isomerism of endothelin in acidic aqueous media: a quantitative NOESY analysis NH Andersen, C Chen, TM Marschner, SR Krystek Jr, DA Bassolino Biochemistry 31 (5), 1280-1295, 1992 | 135 | 1992 |
| Structures of adnectin/protein complexes reveal an expanded binding footprint V Ramamurthy, SR Krystek, A Bush, A Wei, SL Emanuel, RD Gupta, ... Structure 20 (2), 259-269, 2012 | 119 | 2012 |
| AggScore: prediction of aggregation‐prone regions in proteins based on the distribution of surface patches K Sankar, SR Krystek Jr, SM Carl, T Day, JKX Maier Proteins: Structure, Function, and Bioinformatics 86 (11), 1147-1156, 2018 | 106 | 2018 |
| High-throughput and virtual screening: core lead discovery technologies move towards integration AC Good, SR Krystek, JS Mason Drug discovery today 5, S61-S69, 2000 | 102 | 2000 |
| Mapping the energetic epitope of an antibody/interleukin-23 interaction with hydrogen/deuterium exchange, fast photochemical oxidation of proteins mass spectrometry, and … J Li, H Wei, SR Krystek Jr, D Bond, TM Brender, D Cohen, J Feiner, ... Analytical chemistry 89 (4), 2250-2258, 2017 | 91 | 2017 |
| Polynucleotides and polypeptides encoding a novel metalloprotease, Protease-40b J Chen, S Krystek, J Feder, T Nelson US Patent App. 10/980,669, 2005 | 90 | 2005 |
| Mutation of peptide binding site in transmembrane region of a G protein-coupled receptor accounts for endothelin receptor subtype selectivity. SR Krystek Jr, PS Patel, PM Rose, SM Fisher, BK Kienzle, DA Lach, ... Journal of Biological Chemistry 269 (17), 12383-12386, 1994 | 88 | 1994 |
| Isomerization and oxidation in the complementarity-determining regions of a monoclonal antibody: a study of the modification–structure–function correlations by hydrogen … Y Yan, H Wei, Y Fu, S Jusuf, M Zeng, R Ludwig, SR Krystek Jr, G Chen, ... Analytical chemistry 88 (4), 2041-2050, 2016 | 87 | 2016 |
| Discovery of Potent, Orally-Active, and Muscle-Selective Androgen Receptor Modulators Based on an N-Aryl-hydroxybicyclohydantoin Scaffold C Sun, JA Robl, TC Wang, Y Huang, JE Kuhns, JA Lupisella, BC Beehler, ... Journal of medicinal chemistry 49 (26), 7596-7599, 2006 | 82 | 2006 |
| Method for the treatment of a condition remediable by administration of a selective androgen receptor modulator ME Salvati, MM Gottardis, RM Attar, SR Krystek Jr, JS Sack US Patent 6,960,474, 2005 | 82 | 2005 |
| Structure based approach to the design of bicyclic-1H-isoindole-1,3(2H)-dione based androgen receptor antagonists ME Salvati, A Balog, W Shan, DD Wei, D Pickering, RM Attar, J Geng, ... Bioorganic & medicinal chemistry letters 15 (2), 271-276, 2005 | 74 | 2005 |
| Metalloprotease highly expressed in the testis, MMP-29 S Wu, J Chen, JN Feder, L Lee, SR Krystek US Patent 7,285,633, 2007 | 72 | 2007 |
| Discovery of potent and muscle selective androgen receptor modulators through scaffold modifications JJ Li, JC Sutton, A Nirschl, Y Zou, H Wang, C Sun, Z Pi, R Johnson, ... Journal of medicinal chemistry 50 (13), 3015-3025, 2007 | 64 | 2007 |
| Conformation of endothelin in aqueous ethylene glycol determined by 1H-NMR and molecular dynamics simulations SR Krystek Jr, DA Bassolino, J Novotny, C Chen, TM Marschner, ... FEBS letters 281 (1-2), 212-218, 1991 | 59 | 1991 |
| Inhibitors of 11-beta hydroxysteroid dehydrogenase type I J Li, L Hamann, Z Ruan, C Cooper, S Wu, L Simpkins, H Wang, ... US Patent App. 11/403,092, 2006 | 52 | 2006 |