Suivre
Karthik mallilankaraman
Karthik mallilankaraman
University of Pennsylvania Perlman School of Medicine
Adresse e-mail validée de pennmedicine.upenn.edu
Titre
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Année
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
110792021
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca2+ uptake that regulates cell survival
K Mallilankaraman, P Doonan, C Cárdenas, HC Chandramoorthy, ...
Cell 151 (3), 630-644, 2012
6972012
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
K Mallilankaraman, C Cárdenas, PJ Doonan, HC Chandramoorthy, ...
Nature cell biology 14 (12), 1336-1343, 2012
5782012
S-glutathionylation activates STIM1 and alters mitochondrial homeostasis
BJ Hawkins, KM Irrinki, K Mallilankaraman, YC Lien, Y Wang, ...
Journal of Cell Biology 190 (3), 391-405, 2010
2672010
Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation
RK Gandhirajan, S Meng, HC Chandramoorthy, K Mallilankaraman, ...
The Journal of clinical investigation 123 (2), 2013
2332013
A DNA vaccine against chikungunya virus is protective in mice and induces neutralizing antibodies in mice and nonhuman primates
K Mallilankaraman, DJ Shedlock, H Bao, OU Kawalekar, P Fagone, ...
PLoS neglected tropical diseases 5 (1), e928, 2011
2192011
PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy
SHM Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R ...
Cell Research, 1-16, 2018
169*2018
EMRE is a matrix Ca2+ sensor that governs gatekeeping of the mitochondrial Ca2+ uniporter
H Vais, K Mallilankaraman, DOD Mak, H Hoff, R Payne, JE Tanis, ...
Cell reports 14 (3), 403-410, 2016
1692016
SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress–mediated cell death
NE Hoffman, HC Chandramoorthy, S Shanmughapriya, XQ Zhang, ...
Molecular biology of the cell 25 (6), 936-947, 2014
1592014
Inflammasomes: sensors of metabolic stresses for vascular inflammation
Y Yin, JL Pastrana, X Li, X Huang, ET Choi, M Madesh, H Wang, XF Yang
Frontiers in bioscience: a journal and virtual library 18, 638, 2013
1542013
NF-κB protects cells from interferon-γ-induced RIP1-dependent necroptosis.
RJ Thapa, S Basagoudanavar, S Nogusa, K Irrinki, K Mallilankaraman, ...
Molecular and cellular biology, MCB. 05445-11, 2011
153*2011
MICU1 motifs define mitochondrial calcium uniporter binding and activity
NE Hoffman, HC Chandramoorthy, S Shamugapriya, X Zhang, S Rajan, ...
Cell reports 5 (6), 1576-1588, 2013
1502013
Requirement of FADD, NEMO and BAX/BAK for aberrant mitochondrial function in TNFα-induced necrosis
KM Irrinki, K Mallilankaraman, RJ Thapa, HC Chandramoorthy, FJ Smith, ...
Molecular and cellular biology, MCB. 05303-11, 2011
1242011
TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria
BA Miller, NE Hoffman, S Merali, XQ Zhang, JF Wang, S Rajan, ...
Journal of Biological Chemistry 289 (11), 7615-7629, 2014
1032014
MCUR1, CCDC90A, is a regulator of the mitochondrial calcium uniporter
H Vais, JE Tanis, M Müller, R Payne, K Mallilankaraman, JK Foskett
Cell metabolism 22 (4), 533-535, 2015
982015
Hyperhomocysteinemia impairs endothelium-derived hyperpolarizing factor–mediated vasorelaxation in transgenic cystathionine beta synthase–deficient mice
Z Cheng, X Jiang, WD Kruger, D Praticò, S Gupta, K Mallilankaraman, ...
Blood, The Journal of the American Society of Hematology 118 (7), 1998-2006, 2011
902011
Hyperhomocysteinemia and hyperglycemia induce and potentiate endothelial dysfunction via μ-calpain activation
Z Cheng, X Jiang, M Pansuria, P Fang, J Mai, K Mallilankaraman, ...
Diabetes 64 (3), 947-959, 2015
892015
The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury
BA Miller, JF Wang, I Hirschler-Laszkiewicz, E Gao, J Song, XQ Zhang, ...
American Journal of Physiology-Heart and Circulatory Physiology 304 (7 …, 2013
812013
Inhibition of the cardiomyocyte-specific kinase TNNI3K limits oxidative stress, injury, and adverse remodeling in the ischemic heart
RJ Vagnozzi, GJ Gatto Jr, LS Kallander, NE Hoffman, K Mallilankaraman, ...
Science translational medicine 5 (207), 207ra141-207ra141, 2013
742013
Epigenetic regulation of microglial phosphatidylinositol 3‐kinase pathway involved in long‐term potentiation and synaptic plasticity in rats
G Saw, K Krishna, N Gupta, TW Soong, K Mallilankaraman, S Sajikumar, ...
Glia 68 (3), 656-669, 2020
722020
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