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Christopher Boddy
Christopher Boddy
Department of Chemistry, University of Ottawa
Adresse e-mail validée de uottawa.ca - Page d'accueil
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Chemistry, biology, and medicine of the glycopeptide antibiotics
KC Nicolaou, CNC Boddy, S Bräse, N Winssinger
Angewandte Chemie International Edition 38 (15), 2096-2152, 1999
8891999
Portable, on-demand biomolecular manufacturing
K Pardee, S Slomovic, PQ Nguyen, JW Lee, N Donghia, D Burrill, ...
Cell 167 (1), 248-259. e12, 2016
3852016
Extending synthetic access to proteins with a removable acyl transfer auxiliary
J Offer, CNC Boddy, PE Dawson
Journal of the American Chemical Society 124 (17), 4642-4646, 2002
3332002
Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli
K Watanabe, K Hotta, AP Praseuth, K Koketsu, A Migita, CN Boddy, ...
Nature chemical biology 2 (8), 423-428, 2006
2862006
Total Synthesis of Vancomycin Aglycon—Part 1: Synthesis of Amino Acids 4–7 and Construction of the AB‐COD Ring Skeleton
KC Nicolaou, S Natarajan, H Li, NF Jain, R Hughes, ME Solomon, ...
Angewandte Chemie International Edition 37 (19), 2708-2714, 1998
249*1998
Total synthesis of vancomycin—part 1: design and development of methodology
KC Nicolaou, H Li, CNC Boddy, JM Ramanjulu, TY Yue, S Natarajan, ...
Chemistry–A European Journal 5 (9), 2584-2601, 1999
2481999
New synthetic technology for the synthesis of aryl ethers: construction of COD and DOE ring model systems of vancomycin
KC Nicolaou, CNC Boddy, S Natarajan, TY Yue, H Li, S Bräse, ...
Journal of the American Chemical Society 119 (14), 3421-3422, 1997
1961997
Total synthesis of vancomycin—Part 2: Retrosynthetic analysis, synthesis of amino acid building blocks and strategy evaluations
KC Nicolaou, CNC Boddy, H Li, AE Koumbis, R Hughes, S Natarajan, ...
Chemistry–A European Journal 5 (9), 2602-2621, 1999
1921999
Chemie, Biologie und medizinische Anwendungen der Glycopeptid‐Antibiotika
KC Nicolaou, CNC Boddy, S Bräse, N Winssinger
Angewandte Chemie 111 (15), 2230-2287, 1999
1921999
Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?
ME Horsman, TPA Hari, CN Boddy
Natural product reports 33 (2), 183-202, 2016
1902016
ClusterMine360: a database of microbial PKS/NRPS biosynthesis
KR Conway, CN Boddy
Nucleic acids research 41 (D1), D402-D407, 2012
1712012
Atropselective macrocyclization of diaryl ether ring systems: application to the synthesis of vancomycin model systems
KC Nicolaou, CNC Boddy
Journal of the American Chemical Society 124 (35), 10451-10455, 2002
1372002
Trapping biosynthetic acyl-enzyme intermediates with encoded 2, 3-diaminopropionic acid
N Huguenin-Dezot, DA Alonzo, GW Heberlig, M Mahesh, DP Nguyen, ...
Nature 565 (7737), 112-117, 2019
1172019
Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides
CN Boddy
Journal of Industrial Microbiology and Biotechnology 41 (2), 443-450, 2014
1092014
Total Synthesis of Crystalline (.+-.)-Fredericamycin A. Use of Radical Spirocyclization
DLJ Clive, Y Tao, A Khodabocus, YJ Wu, AG Angoh, SM Bennett, ...
Journal of the American Chemical Society 116 (25), 11275-11286, 1994
97*1994
Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases
K Watanabe, CCC Wang, CN Boddy, DE Cane, C Khosla
Journal of Biological Chemistry 278 (43), 42020-42026, 2003
932003
Precursor-Directed Biosynthesis of Epothilone in Escherichia c oli
CN Boddy, K Hotta, ML Tse, RE Watts, C Khosla
Journal of the American Chemical Society 126 (24), 7436-7437, 2004
912004
Probing the ring size of epothilones: total synthesis of [14]‐,[15]‐,[17]‐, and [18] epothilones A
KC Nicolaou, F Sarabia, S Ninkovic, MRV Finlay, CNC Boddy
Angewandte Chemie International Edition 37 (1‐2), 81-84, 1998
881998
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase
CN Boddy, TL Schneider, K Hotta, CT Walsh, C Khosla
Journal of the American Chemical Society 125 (12), 3428-3429, 2003
832003
Alternative sigma factor over-expression enables heterologous expression of a type II polyketide biosynthetic pathway in Escherichia coli
DC Stevens, KR Conway, N Pearce, LR Villegas-Peñaranda, AG Garza, ...
PloS one 8 (5), e64858, 2013
782013
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