Chemistry, biology, and medicine of the glycopeptide antibiotics KC Nicolaou, CNC Boddy, S Bräse, N Winssinger Angewandte Chemie International Edition 38 (15), 2096-2152, 1999 | 889 | 1999 |
Portable, on-demand biomolecular manufacturing K Pardee, S Slomovic, PQ Nguyen, JW Lee, N Donghia, D Burrill, ... Cell 167 (1), 248-259. e12, 2016 | 385 | 2016 |
Extending synthetic access to proteins with a removable acyl transfer auxiliary J Offer, CNC Boddy, PE Dawson Journal of the American Chemical Society 124 (17), 4642-4646, 2002 | 333 | 2002 |
Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli K Watanabe, K Hotta, AP Praseuth, K Koketsu, A Migita, CN Boddy, ... Nature chemical biology 2 (8), 423-428, 2006 | 286 | 2006 |
Total Synthesis of Vancomycin Aglycon—Part 1: Synthesis of Amino Acids 4–7 and Construction of the AB‐COD Ring Skeleton KC Nicolaou, S Natarajan, H Li, NF Jain, R Hughes, ME Solomon, ... Angewandte Chemie International Edition 37 (19), 2708-2714, 1998 | 249* | 1998 |
Total synthesis of vancomycin—part 1: design and development of methodology KC Nicolaou, H Li, CNC Boddy, JM Ramanjulu, TY Yue, S Natarajan, ... Chemistry–A European Journal 5 (9), 2584-2601, 1999 | 248 | 1999 |
New synthetic technology for the synthesis of aryl ethers: construction of COD and DOE ring model systems of vancomycin KC Nicolaou, CNC Boddy, S Natarajan, TY Yue, H Li, S Bräse, ... Journal of the American Chemical Society 119 (14), 3421-3422, 1997 | 196 | 1997 |
Total synthesis of vancomycin—Part 2: Retrosynthetic analysis, synthesis of amino acid building blocks and strategy evaluations KC Nicolaou, CNC Boddy, H Li, AE Koumbis, R Hughes, S Natarajan, ... Chemistry–A European Journal 5 (9), 2602-2621, 1999 | 192 | 1999 |
Chemie, Biologie und medizinische Anwendungen der Glycopeptid‐Antibiotika KC Nicolaou, CNC Boddy, S Bräse, N Winssinger Angewandte Chemie 111 (15), 2230-2287, 1999 | 192 | 1999 |
Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate? ME Horsman, TPA Hari, CN Boddy Natural product reports 33 (2), 183-202, 2016 | 190 | 2016 |
ClusterMine360: a database of microbial PKS/NRPS biosynthesis KR Conway, CN Boddy Nucleic acids research 41 (D1), D402-D407, 2012 | 171 | 2012 |
Atropselective macrocyclization of diaryl ether ring systems: application to the synthesis of vancomycin model systems KC Nicolaou, CNC Boddy Journal of the American Chemical Society 124 (35), 10451-10455, 2002 | 137 | 2002 |
Trapping biosynthetic acyl-enzyme intermediates with encoded 2, 3-diaminopropionic acid N Huguenin-Dezot, DA Alonzo, GW Heberlig, M Mahesh, DP Nguyen, ... Nature 565 (7737), 112-117, 2019 | 117 | 2019 |
Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides CN Boddy Journal of Industrial Microbiology and Biotechnology 41 (2), 443-450, 2014 | 109 | 2014 |
Total Synthesis of Crystalline (.+-.)-Fredericamycin A. Use of Radical Spirocyclization DLJ Clive, Y Tao, A Khodabocus, YJ Wu, AG Angoh, SM Bennett, ... Journal of the American Chemical Society 116 (25), 11275-11286, 1994 | 97* | 1994 |
Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases K Watanabe, CCC Wang, CN Boddy, DE Cane, C Khosla Journal of Biological Chemistry 278 (43), 42020-42026, 2003 | 93 | 2003 |
Precursor-Directed Biosynthesis of Epothilone in Escherichia c oli CN Boddy, K Hotta, ML Tse, RE Watts, C Khosla Journal of the American Chemical Society 126 (24), 7436-7437, 2004 | 91 | 2004 |
Probing the ring size of epothilones: total synthesis of [14]‐,[15]‐,[17]‐, and [18] epothilones A KC Nicolaou, F Sarabia, S Ninkovic, MRV Finlay, CNC Boddy Angewandte Chemie International Edition 37 (1‐2), 81-84, 1998 | 88 | 1998 |
Epothilone C macrolactonization and hydrolysis are catalyzed by the isolated thioesterase domain of epothilone polyketide synthase CN Boddy, TL Schneider, K Hotta, CT Walsh, C Khosla Journal of the American Chemical Society 125 (12), 3428-3429, 2003 | 83 | 2003 |
Alternative sigma factor over-expression enables heterologous expression of a type II polyketide biosynthetic pathway in Escherichia coli DC Stevens, KR Conway, N Pearce, LR Villegas-Peñaranda, AG Garza, ... PloS one 8 (5), e64858, 2013 | 78 | 2013 |