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Yihao Li
Yihao Li
Research Chief, Beigene
Adresse e-mail validée de beigene.com
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Année
TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis
L Zhang, F Zhou, AG de Vinuesa, EM de Kruijf, WE Mesker, L Hui, ...
Molecular cell 51 (5), 559-572, 2013
2462013
Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling
FF Zhou, Y Drabsch, TJA Dekker, AG De Vinuesa, Y Li, LJAC Hawinkels, ...
Nature communications 5 (1), 3388, 2014
2042014
c-Myb enhances breast cancer invasion and metastasis through the Wnt/β-catenin/Axin2 pathway
Y Li, K Jin, GW van Pelt, H van Dam, X Yu, WE Mesker, P ten Dijke, ...
Cancer research 76 (11), 3364-3375, 2016
1372016
In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy target
X Wang, C Tokheim, SS Gu, B Wang, Q Tang, Y Li, N Traugh, Z Zeng, ...
Cell 184 (21), 5357-5374. e22, 2021
1212021
Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models
Y Li, Y Drabsch, P Pujuguet, J Ren, T van Laar, L Zhang, H van Dam, ...
Breast Cancer Research 17, 1-16, 2015
612015
FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis
F Xie, K Jin, L Shao, Y Fan, Y Tu, Y Li, B Yang, H van Dam, P Ten Dijke, ...
Nature Communications 8 (1), 15021, 2017
492017
Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation
L Zhang, F Zhou, Y Li, Y Drabsch, J Zhang, H van Dam, P ten Dijke
Journal of Biological Chemistry 287 (36), 30701-30710, 2012
482012
HSP70 decreases receptor-dependent phosphorylation of Smad2 and blocks TGF-β-induced epithelial-mesenchymal transition
Y Li, X Kang, Q Wang
Journal of Genetics and Genomics 38 (3), 111-116, 2011
452011
CoBRA: containerized bioinformatics workflow for reproducible ChIP/ATAC-seq analysis
X Qiu, AS Feit, A Feiglin, Y Xie, N Kesten, L Taing, J Perkins, S Gu, Y Li, ...
Genomics, Proteomics and Bioinformatics 19 (4), 652-661, 2021
292021
FGFR-inhibitor-mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance
Y Li, X Qiu, X Wang, H Liu, RC Geck, AK Tewari, T Xiao, A Font-Tello, ...
Nature Cell Biology 23 (11), 1187-1198, 2021
242021
VprBP mitigates TGF-β and Activin signaling by promoting Smurf1-mediated type I receptor degradation
Y Li, C Cui, F Xie, S Kiełbasa, H Mei, M van Dinther, H van Dam, A Bauer, ...
Journal of molecular cell biology 12 (2), 138-151, 2020
162020
CRISPR screens reveal convergent targeting strategies against evolutionarily distinct chemoresistance in cancer
C Zhong, WJ Jiang, Y Yao, Z Li, Y Li, S Wang, X Wang, W Zhu, S Wu, ...
Nature Communications 15 (1), 5502, 2024
32024
Mechanisms regulating TGF-β and Wnt signal transduction in breast cancer
Y Li
Leiden University, 2016
2016
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