| HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency T Schaller, KE Ocwieja, J Rasaiyaah, AJ Price, TL Brady, SL Roth, S Hué, ... PLoS pathogens 7 (12), e1002439, 2011 | 560 | 2011 |
| HIV-1 evades innate immune recognition through specific cofactor recruitment J Rasaiyaah, CP Tan, AJ Fletcher, AJ Price, C Blondeau, L Hilditch, ... Nature 503 (7476), 402-405, 2013 | 536 | 2013 |
| CPSF6 defines a conserved capsid interface that modulates HIV-1 replication AJ Price, AJ Fletcher, T Schaller, T Elliott, KE Lee, VN KewalRamani, ... Public Library of Science 8 (8), e1002896, 2012 | 305 | 2012 |
| Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly AJ Price, DA Jacques, WA McEwan, AJ Fletcher, S Essig, JW Chin, ... PLoS pathogens 10 (10), e1004459, 2014 | 296 | 2014 |
| Sequential ubiquitination and deubiquitination enzymes synchronize the dual sensor and effector functions of TRIM21 AJ Fletcher, DL Mallery, RE Watkinson, CF Dickson, LC James Proceedings of the National Academy of Sciences 112 (32), 10014-10019, 2015 | 126 | 2015 |
| Trivalent RING assembly on retroviral capsids activates TRIM5 ubiquitination and innate immune signaling AJ Fletcher, M Vaysburd, S Maslen, J Zeng, JM Skehel, GJ Towers, ... Cell host & microbe 24 (6), 761-775. e6, 2018 | 97 | 2018 |
| TRIM 5α requires Ube2W to anchor Lys63‐linked ubiquitin chains and restrict reverse transcription AJ Fletcher, DE Christensen, C Nelson, CP Tan, T Schaller, PJ Lehner, ... The EMBO journal 34 (15), 2078-2095, 2015 | 95 | 2015 |
| Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21 C Dickson, AJ Fletcher, M Vaysburd, JC Yang, DL Mallery, J Zeng, ... Elife 7, e32660, 2018 | 87 | 2018 |
| Cyclophilin A levels dictate infection efficiency of human immunodeficiency virus type 1 capsid escape mutants A92E and G94D LMJ Ylinen, T Schaller, A Price, AJ Fletcher, M Noursadeghi, LC James, ... Journal of Virology 83 (4), 2044-2047, 2009 | 75 | 2009 |
| Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity PD Mabbitt, A Loreto, MA Déry, AJ Fletcher, M Stanley, KC Pao, NT Wood, ... Nature chemical biology 16 (11), 1227-1236, 2020 | 63 | 2020 |
| Drosophila pico and its mammalian ortholog lamellipodin activate serum response factor and promote cell proliferation E Lyulcheva, E Taylor, M Michael, A Vehlow, S Tan, A Fletcher, M Krause, ... Developmental cell 15 (5), 680-690, 2008 | 60 | 2008 |
| Coordinated neutralization and immune activation by the cytosolic antibody receptor TRIM21 AJ Fletcher, LC James Journal of virology 90 (10), 4856-4859, 2016 | 50 | 2016 |
| Endoplasmic reticulum degradation–enhancing α‐mannosidase–like protein 1 targets misfolded HLA–B27 dimers for endoplasmic reticulum–associated degradation DB Guiliano, H Fussell, I Lenart, E Tsao, D Nesbeth, AJ Fletcher, ... Arthritis & rheumatology 66 (11), 2976-2988, 2014 | 43 | 2014 |
| Inhibition of retroviral replication by members of the TRIM protein family AJ Fletcher, GJ Towers Intrinsic Immunity, 29-66, 2013 | 38 | 2013 |
| Hare TRIM5α restricts divergent retroviruses and exhibits significant sequence variation from closely related lagomorpha TRIM5 genes AJ Fletcher, S Hué, T Schaller, D Pillay, GJ Towers Journal of virology 84 (23), 12463-12468, 2010 | 35 | 2010 |
| Photocrosslinking activity-based probes for ubiquitin RING E3 ligases S Mathur, AJ Fletcher, E Branigan, RT Hay, S Virdee Cell Chemical Biology 27 (1), 74-82. e6, 2020 | 34 | 2020 |
| Antibodies attenuate the capacity of dendritic cells to stimulate HIV-specific cytotoxic T lymphocytes W Posch, S Cardinaud, C Hamimi, A Fletcher, A Mühlbacher, K Loacker, ... Journal of allergy and clinical immunology 130 (6), 1368-1374. e2, 2012 | 33 | 2012 |
| Inhibition of human immunodeficiency virus replication by cell membrane-crossing oligomers W Posch, S Piper, T Lindhorst, B Werner, A Fletcher, H Bock, C Lass-Flörl, ... Molecular Medicine 18, 111-122, 2012 | 7 | 2012 |
| EDEM1 targets misfolded HLA-B27 dimers for endoplasmic reticulum associated degradation DB Guiliano, H Fussell, I Lenart, E Tsao, D Nesbeth, AJ Fletcher, ... Arthritis & rheumatology (Hoboken, NJ) 66 (11), 2976, 2014 | 2 | 2014 |
