Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2 XJ Wang, Z Sun, NF Villeneuve, S Zhang, F Zhao, Y Li, W Chen, X Yi, ... Carcinogenesis 29 (6), 1235-1243, 2008 | 971 | 2008 |
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62 A Lau, XJ Wang, F Zhao, NF Villeneuve, T Wu, T Jiang, Z Sun, E White, ... Molecular and cellular biology 30 (13), 3275-3285, 2010 | 900 | 2010 |
Dual roles of Nrf2 in cancer A Lau, NF Villeneuve, Z Sun, PK Wong, DD Zhang Pharmacological research 58 (5-6), 262-270, 2008 | 808 | 2008 |
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism D Feng, T Liu, Z Sun, A Bugge, SE Mullican, T Alenghat, XS Liu, MA Lazar Science's STKE 331 (6022), 1315, 2011 | 757 | 2011 |
Direct interaction between Nrf2 and p21Cip1/WAF1 upregulates the Nrf2-mediated antioxidant response W Chen, Z Sun, XJ Wang, T Jiang, Z Huang, D Fang, DD Zhang Molecular cell 34 (6), 663-673, 2009 | 731 | 2009 |
Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response Z Sun, YE Chin, DD Zhang Molecular and cellular biology, 2009 | 444 | 2009 |
Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response Z Sun, Z Huang, DD Zhang PloS one 4 (8), e6588, 2009 | 398 | 2009 |
Keap1 controls postinduction repression of the Nrf2-mediated antioxidant response by escorting nuclear export of Nrf2 Z Sun, S Zhang, JY Chan, DD Zhang Molecular and cellular biology, 2007 | 394 | 2007 |
Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway DD Zhang, SC Lo, Z Sun, GM Habib, MW Lieberman, M Hannink Journal of Biological Chemistry 280 (34), 30091-30099, 2005 | 359 | 2005 |
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration Z Sun, RA Miller, RT Patel, J Chen, R Dhir, H Wang, D Zhang, MJ Graham, ... Nature Medicine 18 (6), 934-942, 2012 | 357 | 2012 |
Discrete functions of nuclear receptor Rev-erbα couple metabolism to the clock Y Zhang, B Fang, MJ Emmett, M Damle, Z Sun, D Feng, SM Armour, ... Science 348 (6242), 1488-1492, 2015 | 332 | 2015 |
Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor Z Sun, D Feng, B Fang, SE Mullican, SH You, HW Lim, LJ Everett, ... Molecular cell 52 (6), 769-782, 2013 | 261 | 2013 |
Circadian enhancers coordinate multiple phases of rhythmic gene transcription in vivo B Fang, LJ Everett, J Jager, E Briggs, SM Armour, D Feng, A Roy, ... Cell 159 (5), 1140-1152, 2014 | 234 | 2014 |
Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo SH You, HW Lim, Z Sun, M Broache, KJ Won, MA Lazar Nature structural & molecular biology 20 (2), 182-187, 2013 | 226 | 2013 |
Genome-nuclear lamina interactions regulate cardiac stem cell lineage restriction A Poleshko, PP Shah, M Gupta, A Babu, MP Morley, LJ Manderfield, ... Cell 171 (3), 573-587. e14, 2017 | 200 | 2017 |
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer NA Zhao, J Cao, L Xu, Q Tang, LE Dobrolecki, X Lv, M Talukdar, Y Lu, ... The Journal of clinical investigation 128 (4), 1283-1299, 2018 | 195 | 2018 |
Dissociating fatty liver and diabetes Z Sun, MA Lazar Trends in Endocrinology & Metabolism 24 (1), 4-12, 2013 | 169 | 2013 |
Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1–Cul3 interaction XJ Wang, Z Sun, W Chen, Y Li, NF Villeneuve, DD Zhang Toxicology and applied pharmacology 230 (3), 383-389, 2008 | 158 | 2008 |
KPNA6 (Importin α7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response Z Sun, T Wu, F Zhao, A Lau, CM Birch, DD Zhang Molecular and cellular biology, 2011 | 135 | 2011 |
USP15 negatively regulates Nrf2 through deubiquitination of Keap1 NF Villeneuve, W Tian, T Wu, Z Sun, A Lau, E Chapman, D Fang, ... Molecular cell 51 (1), 68-79, 2013 | 124 | 2013 |