| Protein tyrosine kinase regulation by ubiquitination: critical roles of Cbl-family ubiquitin ligases B Mohapatra, G Ahmad, S Nadeau, N Zutshi, W An, S Scheffe, L Dong, ... Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1833 (1), 122-139, 2013 | 245 | 2013 |
| Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC) CM Robb, JI Contreras, S Kour, MA Taylor, M Abid, YA Sonawane, ... Chemical communications 53 (54), 7577-7580, 2017 | 227 | 2017 |
| Novel arylsulfoanilide− oxindole hybrid as an anticancer agent that inhibits translation initiation A Natarajan, Y Guo, F Harbinski, YH Fan, H Chen, L Luus, J Diercks, ... Journal of medicinal chemistry 47 (21), 4979-4982, 2004 | 200 | 2004 |
| Impact of structurally modifying hyaluronic acid on CD44 interaction DS Bhattacharya, D Svechkarev, JJ Souchek, TK Hill, MA Taylor, ... Journal of Materials Chemistry B 5 (41), 8183-8192, 2017 | 179 | 2017 |
| Cyclin dependent kinase 9 inhibitors for cancer therapy: miniperspective YA Sonawane, MA Taylor, JV Napoleon, S Rana, JI Contreras, ... Journal of medicinal chemistry 59 (19), 8667-8684, 2016 | 154 | 2016 |
| Selective degradation of CDK6 by a palbociclib based PROTAC S Rana, M Bendjennat, S Kour, HM King, S Kizhake, M Zahid, ... Bioorganic & medicinal chemistry letters 29 (11), 1375-1379, 2019 | 124 | 2019 |
| 3, 3-Diaryl-1, 3-dihydroindol-2-ones as antiproliferatives mediated by translation initiation inhibition A Natarajan, YH Fan, H Chen, Y Guo, J Iyasere, F Harbinski, WJ Christ, ... Journal of medicinal chemistry 47 (8), 1882-1885, 2004 | 119 | 2004 |
| Isatin derived spirocyclic analogues with α-methylene-γ-butyrolactone as anticancer agents: a structure–activity relationship study S Rana, EC Blowers, C Tebbe, JI Contreras, P Radhakrishnan, S Kizhake, ... Journal of medicinal chemistry 59 (10), 5121-5127, 2016 | 106 | 2016 |
| Anticancer activity of Celastrol in combination with ErbB2-targeted therapeutics for treatment of ErbB2-overexpressing breast cancers SM Raja, RJ Clubb, C Ortega-Cava, SH Williams, TA Bailey, L Duan, ... Cancer biology & therapy 11 (2), 263-276, 2011 | 84 | 2011 |
| RAC1 GTPase promotes the survival of breast cancer cells in response to hyper-fractionated radiation treatment AL Hein, CM Post, YM Sheinin, I Lakshmanan, A Natarajan, CA Enke, ... Oncogene 35 (49), 6319-6329, 2016 | 78 | 2016 |
| Small molecule adenosine 5′-monophosphate activated protein kinase (AMPK) modulators and human diseases S Rana, EC Blowers, A Natarajan Journal of medicinal chemistry 58 (1), 2-29, 2015 | 77 | 2015 |
| Perturbing pro-survival proteins using quinoxaline derivatives: A structure–activity relationship study R Rajule, VC Bryant, H Lopez, X Luo, A Natarajan Bioorganic & medicinal chemistry 20 (7), 2227-2234, 2012 | 68 | 2012 |
| Synthesis and biological evaluation of thiazolidine-2, 4-dione and 2, 4-thione derivatives as inhibitors of translation initiation H Chen, YH Fan, A Natarajan, Y Guo, J Iyasere, F Harbinski, L Luus, ... Bioorganic & medicinal chemistry letters 14 (21), 5401-5405, 2004 | 67 | 2004 |
| Human apurinic/apyrimidinic endonuclease (APE1) is acetylated at DNA damage sites in chromatin, and acetylation modulates its DNA repair activity S Roychoudhury, S Nath, H Song, ML Hegde, LJ Bellot, AK Mantha, ... Molecular and cellular biology 37 (6), e00401-16, 2017 | 63 | 2017 |
| Micellar formulation of indocyanine green for phototherapy of melanoma V Mundra, Y Peng, S Rana, A Natarajan, RI Mahato Journal of Controlled Release 220, 130-140, 2015 | 61 | 2015 |
| Synthetic Studies toward Aryl-(4-aryl-4H-[1,2,4]triazole-3-yl)-amine from 1,3-Diarylthiourea as Urea Mimetics A Natarajan, Y Guo, H Arthanari, G Wagner, JA Halperin, M Chorev The Journal of organic chemistry 70 (16), 6362-6368, 2005 | 57 | 2005 |
| Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders M Naramura, S Nadeau, B Mohapatra, G Ahmad, C Mukhopadhyay, ... Oncotarget 2 (3), 245, 2011 | 55 | 2011 |
| 2, 3-Substituted quinoxalin-6-amine analogs as antiproliferatives: a structure–activity relationship study Q Chen, VC Bryant, H Lopez, DL Kelly, X Luo, A Natarajan Bioorganic & medicinal chemistry letters 21 (7), 1929-1932, 2011 | 52 | 2011 |
| Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT–phosphoprotein interaction A Simeonov, A Yasgar, A Jadhav, GL Lokesh, C Klumpp, S Michael, ... Analytical biochemistry 375 (1), 60-70, 2008 | 51 | 2008 |
| Structure–activity requirements for the antiproliferative effect of troglitazone derivatives mediated by depletion of intracellular calcium YH Fan, H Chen, A Natarajan, Y Guo, F Harbinski, J Iyasere, W Christ, ... Bioorganic & medicinal chemistry letters 14 (10), 2547-2550, 2004 | 50 | 2004 |
Sandeep RanaNCATS/ NIHAdresse e-mail validée de nih.gov
