Bosch Jürgen

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Coauteurs

Lauren E. BoucherAbbVieAdresse e-mail validée de abbvie.com
Daniel J. KlionskyUniversity of MichiganAdresse e-mail validée de umich.edu
Wesley Van VoorhisProfessor of Medicine, Univ of WAAdresse e-mail validée de uw.edu
Daisy D Colon-LopezJohns Hopkins UniversityAdresse e-mail validée de jhu.edu
Christophe LMJ VerlindeAssociate professor of Biochemistry, University of Washington, SeattleAdresse e-mail validée de u.washington.edu
Ethan A MerrittResearch Associate Professor, Biochemistry, University of WashingtonAdresse e-mail validée de u.washington.edu
liz wortheyuabAdresse e-mail validée de uabmc.edu
Peter J MylerUniversity of WashingtonAdresse e-mail validée de seattlechildrens.org
Joseph R LuftHauptman-WoodwardAdresse e-mail validée de hwi.buffalo.edu
Caren Freel MeyersJohns Hopkins School of MedicineAdresse e-mail validée de jhmi.edu
Michael MatunisJohns Hopkins University, Bloomberg School of Public HealthAdresse e-mail validée de jhu.edu
Craig HodgesCase Western Reserve UniversityAdresse e-mail validée de case.edu
Carlos Andres BuscagliaIIBio (UNSAM-CONICET)Adresse e-mail validée de iib.unsam.edu.ar
Akhil B VaidyaProfessor of Microbiology and Immunology, Drexel University College of Medicine, PhiladelphiaAdresse e-mail validée de drexelmed.edu
Isabelle CoppensJohns Hopkins UniversityAdresse e-mail validée de jhsph.edu
David FidockProfessor of Microbiology & Immunology and of Medical Sciences (in Medicine), Columbia UniversityAdresse e-mail validée de columbia.edu
David BarteeNational Center for Advancing Translational Sciences (NCATS)Adresse e-mail validée de nih.gov
Craig A. TownsendA. H. Corwin Professor of Chemistry, Johns Hopkins UniversityAdresse e-mail validée de jhu.edu
George DimopoulosProfessor, Bloomberg School of Public Health, Johns Hopkins UniversityAdresse e-mail validée de jhu.edu
Raúl G. SaraivaJohns Hopkins Bloomberg School of Public HealthAdresse e-mail validée de jhu.edu

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Bosch Jürgen

Case Western Reserve University & Johns Hopkins University

Adresse e-mail validée de case.edu

Malaria Cancer CFTR Antifungals Protein-protein interaction X-ray crystallography Structure based drug design


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ... Autophagy 12 (1), 1-222, 2016	13970*	2016
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016	311	2016
The apicomplexan glideosome and adhesins – Structures and function LE Boucher, J Bosch Journal of Structural Biology, 2015	128	2015
Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite J Bosch, CA Buscaglia, B Krumm, BP Ingason, R Lucas, C Roach, ... Proceedings of the National Academy of Sciences 104 (17), 7015-7020, 2007	109	2007
Structure of the MTIP–MyoA complex, a key component of the malaria parasite invasion motor J Bosch, S Turley, TM Daly, SM Bogh, ML Villasmil, C Roach, N Zhou, ... Proceedings of the National Academy of Sciences 103 (13), 4852-4857, 2006	89	2006
Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase J Bosch, MA Robien, C Mehlin, E Boni, A Riechers, FS Buckner, ... Journal of medicinal chemistry 49 (20), 5939-5946, 2006	78	2006
The closed MTIP-myosin A-tail complex from the malaria parasite invasion machinery J Bosch, S Turley, CM Roach, TM Daly, LW Bergman, WGJ Hol Journal of molecular biology 372 (1), 77-88, 2007	68	2007
Microfluidic assessment of red blood cell mediated microvascular occlusion Y Man, E Kucukal, R An, QD Watson, J Bosch, PA Zimmerman, JA Little, ... Lab on a Chip 20 (12), 2086-2099, 2020	63	2020
Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction AUP Hain, RR Weltzer, H Hammond, B Jayabalasingham, RR Dinglasan, ... Journal of structural biology 180 (3), 551-562, 2012	61	2012
Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum … JB AU Hain, D Bartee, NG Sanders, AS Miller,DJ Sullivan, J Levitskaya, CF Meyers Journal of Medicinal Chemistry 57 (11), 4521–4531, 2014	55	2014
Crystal structure of glyceraldehyde‐3‐phosphate dehydrogenase from Plasmodium falciparum at 2.25 Å resolution reveals intriguing extra electron density in the active site MA Robien, J Bosch, FS Buckner, WCE Van Voorhis, EA Worthey, P Myler, ... Proteins: Structure, Function, and Bioinformatics 62 (3), 570-577, 2006	52	2006
Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin RG Saraiva, CR Huitt-Roehl, A Tripathi, YQ Cheng, J Bosch, ... Scientific reports 8 (1), 6176, 2018	49	2018
Autophagy in Plasmodium, a multifunctional pathway? AUP Hain, J Bosch Computational and structural biotechnology journal 8 (11), e201308002, 2013	44	2013
DXP Synthase‐Catalyzed C N Bond Formation: Nitroso Substrate Specificity Studies Guide Selective Inhibitor Design F Morris, R Vierling, L Boucher, J Bosch, CL Freel Meyers ChemBioChem 14 (11), 1309-1315, 2013	44	2013
Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium CLMJ Verlinde, E Fan, S Shibata, Z Zhang, Z Sun, W Deng, J Ross, J Kim, ... Current topics in medicinal chemistry 9 (18), 1678-1687, 2009	44	2009
Structural genomics of pathogenic protozoa: an overview E Fan, D Baker, S Fields, MH Gelb, FS Buckner, WC Van Voorhis, ... Structural Proteomics: High-Throughput Methods, 497-513, 2008	41	2008
Characterization of the ATG8-conjugation system in 2 Plasmodium species with special focus on the liver stage: possible linkage between the apicoplastic and autophagic systems? B Jayabalasingham, C Voss, K Ehrenman, JD Romano, ME Smith, ... Autophagy 10 (2), 269-284, 2014	40	2014
High-throughput activity assay for screening inhibitors of the SARS-CoV-2 Mac1 macrodomain M Dasovich, J Zhuo, JA Goodman, A Thomas, RL McPherson, ... ACS chemical biology 17 (1), 17-23, 2021	38	2021
Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum J Bosch, MH Paige, AB Vaidya, LW Bergman, WGJ Hol Journal of structural biology 178 (1), 61-73, 2012	38	2012
Structure of a ribulose 5‐phosphate 3‐epimerase from Plasmodium falciparum J Caruthers, J Bosch, F Buckner, W Van Voorhis, P Myler, E Worthey, ... PROTEINS: Structure, Function, and Bioinformatics 62 (2), 338-342, 2006	35	2006

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