| Relating structure to mechanism in creatine kinase MJ McLeish, GL Kenyon Critical reviews in biochemistry and molecular biology 40 (1), 1-20, 2005 | 266 | 2005 |
| The Crystal Structure of Benzoylformate Decarboxylase at 1.6 Å Resolution: Diversity of Catalytic Residues in Thiamin Diphosphate-Dependent Enzymes, MS Hasson, A Muscate, MJ McLeish, LS Polovnikova, JA Gerlt, ... Biochemistry 37 (28), 9918-9930, 1998 | 229 | 1998 |
| Involvement of Electrostatic Interactions in the Mechanism of Peptide Folding Induced by Sodium Dodecyl Sulfate Binding, R Montserret, MJ McLeish, A Böckmann, C Geourjon, F Penin Biochemistry 39 (29), 8362-8373, 2000 | 154 | 2000 |
| The 2.1 Å Structure of Torpedo californica Creatine Kinase Complexed with the ADP-Mg2+−NO3-−Creatine Transition-State Analogue Complex, SD Lahiri, PF Wang, PC Babbitt, MJ McLeish, GL Kenyon, KN Allen Biochemistry 41 (47), 13861-13867, 2002 | 151 | 2002 |
| An unusually low p K a for Cys282 in the active site of human muscle creatine kinase PF Wang, MJ McLeish, MM Kneen, G Lee, GL Kenyon Biochemistry 40 (39), 11698-11705, 2001 | 135 | 2001 |
| Structural and kinetic analysis of catalysis by a thiamin diphosphate-dependent enzyme, benzoylformate decarboxylase ES Polovnikova, MJ McLeish, EA Sergienko, JT Burgner, NL Anderson, ... Biochemistry 42 (7), 1820-1830, 2003 | 125 | 2003 |
| Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida P Siegert, MJ McLeish, M Baumann, H Iding, MM Kneen, GL Kenyon, ... Protein Engineering Design and Selection 18 (7), 345-357, 2005 | 110 | 2005 |
| Characterization of benzaldehyde lyase from Pseudomonas fluorescens: A versatile enzyme for asymmetric C–C bond formation E Janzen, M Müller, D Kolter-Jung, MM Kneen, MJ McLeish, M Pohl Bioorganic chemistry 34 (6), 345-361, 2006 | 96 | 2006 |
| Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents AD Andricopulo, MB Akoachere, R Krogh, C Nickel, MJ McLeish, ... Bioorganic & medicinal chemistry letters 16 (8), 2283-2292, 2006 | 95 | 2006 |
| Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity E Davioud-Charvet, MJ McLeish, DM Veine, D Giegel, LD Arscott, ... Biochemistry 42 (45), 13319-13330, 2003 | 88 | 2003 |
| High-performance liquid chromatographic determination of the alkaloids in betel nut JL Huang, MJ McLeish Journal of Chromatography A 475 (2), 447-450, 1989 | 87 | 1989 |
| Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT JL Martin, J Begun, MJ McLeish, JM Caine, GL Grunewald Structure 9 (10), 977-985, 2001 | 80 | 2001 |
| Elucidation of the chemistry of enzyme-bound thiamin diphosphate prior to substrate binding: defining internal equilibria among tautomeric and ionization states N Nemeria, L Korotchkina, MJ McLeish, GL Kenyon, MS Patel, F Jordan Biochemistry 46 (37), 10739-10744, 2007 | 64 | 2007 |
| Conformational analysis of LYS (11− 36), a peptide derived from the β-sheet region of T4 lysozyme, in TFE and SDS LV Najbar, DJ Craik, JD Wade, D Salvatore, MJ McLeish Biochemistry 36 (38), 11525-11533, 1997 | 61 | 1997 |
| Saturation mutagenesis of putative catalytic residues of benzoylformate decarboxylase provides a challenge to the accepted mechanism A Yep, GL Kenyon, MJ McLeish Proceedings of the National Academy of Sciences 105 (15), 5733-5738, 2008 | 58 | 2008 |
| Characterization of a thiamin diphosphate‐dependent phenylpyruvate decarboxylase from Saccharomyces cerevisiae MM Kneen, R Stan, A Yep, RP Tyler, C Saehuan, MJ McLeish The FEBS Journal 278 (11), 1842-1853, 2011 | 57 | 2011 |
| Spectroscopic detection of transient thiamin diphosphate-bound intermediates on benzoylformate decarboxylase EA Sergienko, J Wang, L Polovnikova, MS Hasson, MJ McLeish, ... Biochemistry 39 (45), 13862-13869, 2000 | 56 | 2000 |
| Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors N Drinkwater, H Vu, KM Lovell, KR Criscione, BM Collins, TE Prisinzano, ... Biochemical Journal 431 (1), 51-61, 2010 | 53 | 2010 |
| Determinants of substrate specificity in KdcA, a thiamin diphosphate-dependent decarboxylase A Yep, GL Kenyon, MJ McLeish Bioorganic chemistry 34 (6), 325-336, 2006 | 52 | 2006 |
| Substrate specificity in thiamin diphosphate-dependent decarboxylases FH Andrews, MJ McLeish Bioorganic chemistry 43, 26-36, 2012 | 50 | 2012 |
