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Jesse Boehm
Jesse Boehm
Institute Scientist, Cancer Program, Broad Institute
Adresse e-mail validée de broadinstitute.org - Page d'accueil
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Année
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
44242010
Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ...
Nature 462 (7269), 108-112, 2009
33322009
A next generation connectivity map: L1000 platform and the first 1,000,000 profiles
A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ...
Cell 171 (6), 1437-1452. e17, 2017
28532017
Next-generation characterization of the cancer cell line encyclopedia
M Ghandi, FW Huang, J Jané-Valbuena, GV Kryukov, CC Lo, ...
Nature 569 (7757), 503-508, 2019
27292019
Defining a cancer dependency map
A Tsherniak, F Vazquez, PG Montgomery, BA Weir, G Kryukov, ...
Cell 170 (3), 564-576. e16, 2017
23452017
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ...
Nature 468 (7326), 968-972, 2010
17512010
Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ...
Nature genetics 49 (12), 1779-1784, 2017
16922017
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ...
Nature 547 (7664), 453-457, 2017
15522017
Organoid modeling of the tumor immune microenvironment
JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ...
Cell 175 (7), 1972-1988. e16, 2018
12062018
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors
VA Adalsteinsson, G Ha, SS Freeman, AD Choudhury, DG Stover, ...
Nature communications 8 (1), 1324, 2017
8772017
CDK8 is a colorectal cancer oncogene that regulates β-catenin activity
R Firestein, AJ Bass, SY Kim, IF Dunn, SJ Silver, I Guney, E Freed, ...
Nature 455 (7212), 547-551, 2008
8162008
Patient-derived xenografts undergo mouse-specific tumor evolution
U Ben-David, G Ha, YY Tseng, NF Greenwald, C Oh, J Shih, ...
Nature genetics 49 (11), 1567-1575, 2017
7522017
Integrative genomic approaches identify IKBKE as a breast cancer oncogene
JS Boehm, JJ Zhao, J Yao, SY Kim, R Firestein, IF Dunn, SK Sjostrom, ...
Cell 129 (6), 1065-1079, 2007
7182007
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis
Y Zou, MJ Palte, AA Deik, H Li, JK Eaton, W Wang, YY Tseng, R Deasy, ...
Nature communications 10 (1), 1617, 2019
6672019
Highly parallel identification of essential genes in cancer cells
B Luo, HW Cheung, A Subramanian, T Sharifnia, M Okamoto, X Yang, ...
Proceedings of the National Academy of Sciences 105 (51), 20380-20385, 2008
6512008
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells
C Scholl, S Fröhling, IF Dunn, AC Schinzel, DA Barbie, SY Kim, SJ Silver, ...
Cell 137 (5), 821-834, 2009
6342009
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer
KM Vasudevan, DA Barbie, MA Davies, R Rabinovsky, CJ McNear, ...
Cancer cell 16 (1), 21-32, 2009
6312009
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer
JG Lohr, VA Adalsteinsson, K Cibulskis, AD Choudhury, M Rosenberg, ...
Nature biotechnology 32 (5), 479-484, 2014
6182014
Somatic ERCC2 Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma
EM Van Allen, KW Mouw, P Kim, G Iyer, N Wagle, H Al-Ahmadie, C Zhu, ...
Cancer discovery 4 (10), 1140-1153, 2014
6172014
Discovering the anticancer potential of non-oncology drugs by systematic viability profiling
SM Corsello, RT Nagari, RD Spangler, J Rossen, M Kocak, JG Bryan, ...
Nature cancer 1 (2), 235-248, 2020
6162020
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