Articles avec mandats d'accès public - Douglas K BrubakerEn savoir plus
Disponibles quelque part : 23
Tissue-specific oncogenic activity of KRASA146T
EJ Poulin, AK Bera, J Lu, YJ Lin, SD Strasser, JA Paulo, TQ Huang, ...
Cancer discovery 9 (6), 738-755, 2019
Exigences : US National Science Foundation, US Department of Energy, US Department of …
Translating preclinical models to humans
DK Brubaker, DA Lauffenburger
Science 367 (6479), 742-743, 2020
Exigences : US National Institutes of Health
Proteogenomic network analysis of context-specific KRAS signaling in mouse-to-human cross-species translation
DK Brubaker, JA Paulo, S Sheth, EJ Poulin, O Popow, BA Joughin, ...
Cell systems 9 (3), 258-270. e6, 2019
Exigences : US National Science Foundation, US National Institutes of Health, Cancer …
Computational translation of genomic responses from experimental model systems to humans
DK Brubaker, EA Proctor, KM Haigis, DA Lauffenburger
PLoS computational biology 15 (1), e1006286, 2019
Exigences : US Department of Defense, US National Institutes of Health
An interspecies translation model implicates integrin signaling in infliximab-resistant inflammatory bowel disease
DK Brubaker, MP Kumar, EL Chiswick, C Gregg, A Starchenko, PN Vega, ...
Science Signaling 13 (643), eaay3258, 2020
Exigences : US Department of Defense, US National Institutes of Health, US Department of …
Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis
J Lyons, DK Brubaker, PC Ghazi, KR Baldwin, A Edwards, M Boukhali, ...
Science signaling 11 (519), eaan3580, 2018
Exigences : US National Science Foundation, US Department of Defense, US National …
Coagulopathy signature precedes and predicts severity of end‐organ heat stroke pathology in a mouse model
EA Proctor, SM Dineen, SC Van Nostrand, MK Kuhn, CD Barrett, ...
Journal of thrombosis and haemostasis 18 (8), 1900-1910, 2020
Exigences : US Department of Defense, US National Institutes of Health
Substrate-based kinase activity inference identifies MK2 as driver of colitis
SD Strasser, PC Ghazi, A Starchenko, M Boukhali, A Edwards, ...
Integrative Biology 11 (7), 301-314, 2019
Exigences : US National Science Foundation, US Department of Defense, US National …
Drug intervention response predictions with PARADIGM (DIRPP) identifies drug resistant cancer cell lines and pathway mechanisms of resistance
D Brubaker, A Difeo, Y Chen, T Pearl, K Zhai, G Bebek, M Chance, ...
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 125, 2014
Exigences : US National Institutes of Health
Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling
AR Berard, DK Brubaker, K Birse, A Lamont, RD Mackelprang, ...
Cell Reports 42 (5), 2023
Exigences : Bill & Melinda Gates Foundation, US Department of Defense, US National …
Integrated microRNA and mRNA network analysis of the human myometrial transcriptome in the transition from quiescence to labor
WE Ackerman IV, IA Buhimschi, D Brubaker, S Maxwell, KM Rood, ...
Biology of Reproduction 98 (6), 834-845, 2018
Exigences : US National Institutes of Health
Finding lost genes in GWAS via integrative—omics analysis reveals novel sub-networks associated with preterm birth
D Brubaker, Y Liu, J Wang, H Tan, G Zhang, B Jacobsson, L Muglia, ...
Human Molecular Genetics 25 (23), 5254-5264, 2016
Exigences : US National Institutes of Health
A dynamical systems model of progesterone receptor interactions with inflammation in human parturition
D Brubaker, A Barbaro, M R. Chance, S Mesiano
BMC systems biology 10, 1-14, 2016
Exigences : US National Institutes of Health
Computational interspecies translation between Alzheimer’s disease mouse models and human subjects identifies innate immune complement, TYROBP, and TAM receptor agonist …
MJ Lee, C Wang, MJ Carroll, DK Brubaker, BT Hyman, DA Lauffenburger
Frontiers in Neuroscience 15, 727784, 2021
Exigences : US National Science Foundation, US Department of Defense, US National …
Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms
JC Kester, DK Brubaker, J Velazquez, C Wright, DA Lauffenburger, ...
Antimicrobial agents and chemotherapy 64 (4), 10.1128/aac. 01404-19, 2020
Exigences : US National Institutes of Health
Endogenous production of hyaluronan, PRG4, and cytokines is sensitive to cyclic loading in synoviocytes
M Pendyala, PS Woods, DK Brubaker, EA Blaber, TA Schmidt, DD Chan
Plos one 17 (12), e0267921, 2022
Exigences : US National Science Foundation
Engineering logical inflammation sensing circuit for gut modulation
LN Merk, AS Shur, A Pandey, RM Murray, LN Green
bioRxiv 10 (2020.11), 10.377085, 2020
Exigences : US National Science Foundation
Frequent subgraph mining of personalized signaling pathway networks groups patients with frequently dysregulated disease pathways and predicts prognosis
A Durmaz, TAD Henderson, D Brubaker, G Bebek
PACIFIC SYMPOSIUM ON BIOCOMPUTING 2017, 402-413, 2017
Exigences : US National Institutes of Health
Cross-Species Modeling Identifies Gene Signatures in Type 2 Diabetes Mouse Models Predictive of Inflammatory and Estrogen Signaling Pathways Associated with Alzheimer’s Disease …
BK Ball, EA Proctor, DK Brubaker
Biocomputing 2025: Proceedings of the Pacific Symposium, 426-440, 2024
Exigences : US National Science Foundation, US National Institutes of Health
Cross-species transcriptomic signatures predict response to MK2 inhibition in mouse models of chronic inflammation
L Suarez-Lopez, B Shui, DK Brubaker, M Hill, A Bergendorf, ...
Iscience 24 (12), 2021
Exigences : US Department of Defense, US National Institutes of Health
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