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Lorenzo Bonaguro
Lorenzo Bonaguro
University of Bonn, DZNE Bonn & UKB Bonn
Adresse e-mail validée de uni-bonn.de
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Severe COVID-19 is marked by a dysregulated myeloid cell compartment
J Schulte-Schrepping, N Reusch, D Paclik, K Baßler, S Schlickeiser, ...
Cell 182 (6), 1419-1440. e23, 2020
13622020
Human monocyte subsets and phenotypes in major chronic inflammatory diseases
TS Kapellos, L Bonaguro, I Gemünd, N Reusch, A Saglam, ER Hinkley, ...
Frontiers in immunology 10, 2035, 2019
8472019
Swarm learning for decentralized and confidential clinical machine learning
S Warnat-Herresthal, H Schultze, KL Shastry, S Manamohan, ...
Nature 594 (7862), 265-270, 2021
6902021
Neutrophils in COVID-19
N Reusch, E De Domenico, L Bonaguro, J Schulte-Schrepping, K Baßler, ...
Frontiers in immunology 12, 652470, 2021
3082021
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
AC Aschenbrenner, M Mouktaroudi, B Krämer, M Oestreich, N Antonakos, ...
Genome medicine 13, 1-25, 2021
2502021
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19
B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe, ...
Immunity 54 (11), 2650-2669. e14, 2021
2022021
Complement activation induces excessive T cell cytotoxicity in severe COVID-19
P Georg, R Astaburuaga-García, L Bonaguro, S Brumhard, L Michalick, ...
Cell 185 (3), 493-512. e25, 2022
1762022
A guide to systems-level immunomics
L Bonaguro, J Schulte-Schrepping, T Ulas, AC Aschenbrenner, M Beyer, ...
Nature immunology 23 (10), 1412-1423, 2022
572022
Suppressive myeloid cells are a hallmark of severe COVID-19
J Schulte-Schrepping, N Reusch, D Paclik, K Baßler, S Schlickeiser, ...
MedRxiv, 2020.06. 03.20119818, 2020
292020
Alveolar macrophages in early stage COPD show functional deviations with properties of impaired immune activation
K Baßler, W Fujii, TS Kapellos, E Dudkin, N Reusch, A Horne, B Reiz, ...
Frontiers in immunology 13, 917232, 2022
232022
Creld2 function during unfolded protein response is essential for liver metabolism homeostasis
P Kern, NR Balzer, F Bender, A Frolov, K Wunderling, JP Sowa, ...
bioRxiv, 2020.01. 28.923136, 2020
232020
CRELD1 modulates homeostasis of the immune system in mice and humans
L Bonaguro, M Köhne, L Schmidleithner, J Schulte-Schrepping, ...
Nature Immunology 21 (12), 1517-1527, 2020
212020
Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease
TS Kapellos, K Baßler, W Fujii, C Nalkurthi, AC Schaar, L Bonaguro, ...
Cell reports 42 (6), 2023
192023
Optimized workflow for single-cell transcriptomics on infectious diseases including COVID-19
E De Domenico, L Bonaguro, J Schulte-Schrepping, M Becker, K Händler, ...
STAR protocols 1 (3), 100233, 2020
172020
Alterations of multiple alveolar macrophage states in chronic obstructive pulmonary disease
K Baßler, W Fujii, TS Kapellos, A Horne, B Reiz, E Dudkin, M Lücken, ...
BioRxiv, 2020.05. 28.121541, 2020
162020
Human monocyte subsets and phenotypes in major chronic inflammatory diseases. Front Immunol. 2019; 10: 2035
TS Kapellos, L Bonaguro, I Gemünd, N Reusch, A Saglam, ER Hinkley, ...
Epub 2019/09/24. https://doi. org/10.3389/fimmu. 2019.02035 PMID: 31543877, 2019
152019
Creld1 regulates myocardial development and function
V Beckert, S Rassmann, AH Kayvanjoo, C Klausen, L Bonaguro, ...
Journal of Molecular and Cellular Cardiology 156, 45-56, 2021
102021
Induction of Rosette-to-Lumen stage embryoids using reprogramming paradigms in ESCs
J Langkabel, A Horne, L Bonaguro, L Holsten, T Hesse, A Knaus, ...
Nature Communications 12 (1), 7322, 2021
92021
Lung T cell response in COVID-19
MH Shakiba, I Gemünd, M Beyer, L Bonaguro
Frontiers in Immunology 14, 1108716, 2023
82023
Faecal microbial transfer and complex carbohydrates mediate protection against COPD
KF Budden, SD Shukla, KL Bowerman, A Vaughan, SL Gellatly, ...
Gut 73 (5), 751-769, 2024
72024
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