| The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ... Nature medicine 21 (10), 1199-1208, 2015 | 452 | 2015 |
| The MLL3/MLL4 branches of the COMPASS family function as major histone H3K4 monomethylases at enhancers D Hu, X Gao, MA Morgan, HM Herz, ER Smith, A Shilatifard Molecular and cellular biology 33 (23), 4745-4754, 2013 | 446 | 2013 |
| Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells S Liu, H Zhang, M Li, D Hu, C Li, B Ge, B Jin, Z Fan Cell Death & Differentiation 20 (3), 456-464, 2013 | 334 | 2013 |
| A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers J Cheng, R Blum, C Bowman, D Hu, A Shilatifard, S Shen, BD Dynlacht Molecular cell 53 (6), 979-992, 2014 | 256 | 2014 |
| Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion Z Li, P Qian, W Shao, H Shi, XC He, M Gogol, Z Yu, Y Wang, M Qi, Y Zhu, ... Cell research 28 (9), 904-917, 2018 | 249 | 2018 |
| The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells D Hu, AS Garruss, X Gao, MA Morgan, M Cook, ER Smith, A Shilatifard Nature structural & molecular biology 20 (9), 1093-1097, 2013 | 210 | 2013 |
| Enhancer malfunction in cancer HM Herz, D Hu, A Shilatifard Molecular cell 53 (6), 859-866, 2014 | 203 | 2014 |
| Integrator regulates transcriptional initiation and pause release following activation A Gardini, D Baillat, M Cesaroni, D Hu, JM Marinis, EJ Wagner, MA Lazar, ... Molecular cell 56 (1), 128-139, 2014 | 188 | 2014 |
| Epigenetics of hematopoiesis and hematological malignancies D Hu, A Shilatifard Genes & development 30 (18), 2021-2041, 2016 | 183 | 2016 |
| Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates W Wang, CK Hu, A Zeng, D Alegre, D Hu, K Gotting, A Ortega Granillo, ... Science 369 (6508), eaaz3090, 2020 | 171 | 2020 |
| A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer D Fantini, AP Glaser, KJ Rimar, Y Wang, M Schipma, N Varghese, ... Oncogene 37 (14), 1911-1925, 2018 | 142 | 2018 |
| Promoter bivalency favors an open chromatin architecture in embryonic stem cells G Mas, E Blanco, C Ballaré, M Sansó, YG Spill, D Hu, Y Aoi, F Le Dily, ... Nature genetics 50 (10), 1452-1462, 2018 | 138 | 2018 |
| PCBP-1 regulates alternative splicing of the CD44 gene and inhibits invasion in human hepatoma cell line HepG2 cells T Zhang, XH Huang, L Dong, D Hu, C Ge, YQ Zhan, WX Xu, M Yu, W Li, ... Molecular Cancer 9, 1-10, 2010 | 127 | 2010 |
| The little elongation complex regulates small nuclear RNA transcription ER Smith, C Lin, AS Garrett, J Thornton, N Mohaghegh, D Hu, J Jackson, ... Molecular cell 44 (6), 954-965, 2011 | 102 | 2011 |
| Not all H3K4 methylations are created equal: Mll2/COMPASS dependency in primordial germ cell specification D Hu, X Gao, K Cao, MA Morgan, G Mas, ER Smith, AG Volk, ET Bartom, ... Molecular cell 65 (3), 460-475. e6, 2017 | 99 | 2017 |
| Codependency of H2B monoubiquitination and nucleosome reassembly on Chd1 JS Lee, AS Garrett, K Yen, YH Takahashi, D Hu, J Jackson, C Seidel, ... Genes & development 26 (9), 914-919, 2012 | 89 | 2012 |
| An evolutionary conserved epigenetic mark of polycomb response elements implemented by Trx/MLL/COMPASS R Rickels, D Hu, CK Collings, AR Woodfin, A Piunti, M Mohan, HM Herz, ... Molecular cell 63 (2), 318-328, 2016 | 77 | 2016 |
| Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis KJ Frankowski, C Wang, S Patnaik, FJ Schoenen, N Southall, D Li, ... Science translational medicine 10 (441), eaap8307, 2018 | 70 | 2018 |
| The little elongation complex functions at initiation and elongation phases of snRNA gene transcription D Hu, ER Smith, AS Garruss, N Mohaghegh, JM Varberg, C Lin, ... Molecular cell 51 (4), 493-505, 2013 | 68 | 2013 |
| BCMab1, A Monoclonal Antibody against Aberrantly Glycosylated Integrin α3β1, Has Potent Antitumor Activity of Bladder Cancer In Vivo C Li, Z Yang, Y Du, H Tang, J Chen, D Hu, Z Fan Clinical cancer research 20 (15), 4001-4013, 2014 | 64 | 2014 |
Ali ShilatifardProfessor and Chairman of Biochemistry, Director of Simpson Querrey Institute for EpigeneticsAdresse e-mail validée de northwestern.edu
