Malaria: progress, perils, and prospects for eradication BM Greenwood, DA Fidock, DE Kyle, SHI Kappe, PL Alonso, FH Collins, ... The Journal of clinical investigation 118 (4), 1266-1276, 2008 | 1088 | 2008 |
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum SJ Foote, DE Kyle, RK Martin, AMJ Oduola, K Forsyth, DJ Kemp, ... Nature 345 (6272), 255-258, 1990 | 778 | 1990 |
Efflux of Chloroquine from Plasmodium falciparum: Mechanism of Chloroquine Resistance DJ Krogstad, IY Gluzman, DE Kyle, AMJ Oduola, SK Martin, WK Milhous, ... Science 238 (4831), 1283-1285, 1987 | 774 | 1987 |
Evidence for the shikimate pathway in apicomplexan parasites F Roberts, CW Roberts, JJ Johnson, DE Kyle, T Krell, JR Coggins, ... Nature 393 (6687), 801-805, 1998 | 639 | 1998 |
Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand S Looareesuwan, C Viravan, HK Webster, DE Kyle, DB Hutchinson, ... The American journal of tropical medicine and hygiene 54 (1), 62-66, 1996 | 519 | 1996 |
A novel multiple-stage antimalarial agent that inhibits protein synthesis B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ... Nature 522 (7556), 315-320, 2015 | 468 | 2015 |
Genetic Diversity of Plasmodium falciparum Histidine-Rich Protein 2 (PfHRP2) and Its Effect on the Performance of PfHRP2-Based Rapid Diagnostic Tests J Baker, J McCarthy, M Gatton, DE Kyle, V Belizario, J Luchavez, D Bell, ... The Journal of infectious diseases 192 (5), 870-877, 2005 | 366 | 2005 |
Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand CM Wilson, SK Volkman, S Thaithong, RK Martin, DE Kyle, WK Milhous, ... Molecular and biochemical parasitology 57 (1), 151-160, 1993 | 359 | 1993 |
Cardiac effects of antimalarial treatment with halofantrine F Nosten, FO Ter Kuile, C Luxemburger, C Woodrow, ... The Lancet 341 (8852), 1054-1056, 1993 | 346 | 1993 |
Artemisone—a highly active antimalarial drug of the artemisinin class RK Haynes, B Fugmann, J Stetter, K Rieckmann, HD Heilmann, HW Chan, ... Angewandte Chemie International Edition 45 (13), 2082-2088, 2006 | 322 | 2006 |
Reversal of Chloroquine Resistance in Malaria Parasite Plasmodium falciparum by Desipramine AJ Bitonti, A Sjoerdsma, PP McCann, DE Kyle, AMJ Oduola, RN Rossan, ... Science 242 (4883), 1301-1303, 1988 | 313 | 1988 |
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 311 | 2016 |
Artemisinin-Induced Dormancy in Plasmodium falciparum: Duration, Recovery Rates, and Implications in Treatment Failure F Teuscher, ML Gatton, N Chen, J Peters, DE Kyle, Q Cheng The Journal of infectious diseases 202 (9), 1362-1368, 2010 | 292 | 2010 |
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ... Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014 | 284 | 2014 |
The epidemiology of malaria in a Karen population on the western border of Thailand C Luxemburger, KL Thwai, NJ White, HK Webster, DE Kyle, L Maelankirri, ... Transactions of the Royal Society of Tropical Medicine and Hygiene 90 (2 …, 1996 | 280 | 1996 |
Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 255 | 2013 |
Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I R McLeod, SP Muench, JB Rafferty, DE Kyle, EJ Mui, MJ Kirisits, DG Mack, ... International journal for parasitology 31 (2), 109-113, 2001 | 255 | 2001 |
Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand F Nosten, C Luxemburger, DE Kyle, WR Ballou, J Wittes, EH Wah, ... The lancet 348 (9029), 701-707, 1996 | 238 | 1996 |
Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America RK Mehlotra, H Fujioka, PD Roepe, O Janneh, LMB Ursos, ... Proceedings of the National Academy of Sciences 98 (22), 12689-12694, 2001 | 236 | 2001 |
The shikimate pathway and its branches in apicomplexan parasites CW Roberts, F Roberts, RE Lyons, MJ Kirisits, EJ Mui, J Finnerty, ... The Journal of infectious diseases 185 (Supplement_1), S25-S36, 2002 | 233 | 2002 |