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Dennis E. Kyle
Dennis E. Kyle
Director, Center for Tropical and Emerging Global Diseases, University of Georgia
Adresse e-mail validée de uga.edu - Page d'accueil
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Malaria: progress, perils, and prospects for eradication
BM Greenwood, DA Fidock, DE Kyle, SHI Kappe, PL Alonso, FH Collins, ...
The Journal of clinical investigation 118 (4), 1266-1276, 2008
10882008
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
SJ Foote, DE Kyle, RK Martin, AMJ Oduola, K Forsyth, DJ Kemp, ...
Nature 345 (6272), 255-258, 1990
7781990
Efflux of Chloroquine from Plasmodium falciparum: Mechanism of Chloroquine Resistance
DJ Krogstad, IY Gluzman, DE Kyle, AMJ Oduola, SK Martin, WK Milhous, ...
Science 238 (4831), 1283-1285, 1987
7741987
Evidence for the shikimate pathway in apicomplexan parasites
F Roberts, CW Roberts, JJ Johnson, DE Kyle, T Krell, JR Coggins, ...
Nature 393 (6687), 801-805, 1998
6391998
Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand
S Looareesuwan, C Viravan, HK Webster, DE Kyle, DB Hutchinson, ...
The American journal of tropical medicine and hygiene 54 (1), 62-66, 1996
5191996
A novel multiple-stage antimalarial agent that inhibits protein synthesis
B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ...
Nature 522 (7556), 315-320, 2015
4682015
Genetic Diversity of Plasmodium falciparum Histidine-Rich Protein 2 (PfHRP2) and Its Effect on the Performance of PfHRP2-Based Rapid Diagnostic Tests
J Baker, J McCarthy, M Gatton, DE Kyle, V Belizario, J Luchavez, D Bell, ...
The Journal of infectious diseases 192 (5), 870-877, 2005
3662005
Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand
CM Wilson, SK Volkman, S Thaithong, RK Martin, DE Kyle, WK Milhous, ...
Molecular and biochemical parasitology 57 (1), 151-160, 1993
3591993
Cardiac effects of antimalarial treatment with halofantrine
F Nosten, FO Ter Kuile, C Luxemburger, C Woodrow, ...
The Lancet 341 (8852), 1054-1056, 1993
3461993
Artemisone—a highly active antimalarial drug of the artemisinin class
RK Haynes, B Fugmann, J Stetter, K Rieckmann, HD Heilmann, HW Chan, ...
Angewandte Chemie International Edition 45 (13), 2082-2088, 2006
3222006
Reversal of Chloroquine Resistance in Malaria Parasite Plasmodium falciparum by Desipramine
AJ Bitonti, A Sjoerdsma, PP McCann, DE Kyle, AMJ Oduola, RN Rossan, ...
Science 242 (4883), 1301-1303, 1988
3131988
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond
WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ...
PLoS pathogens 12 (7), e1005763, 2016
3112016
Artemisinin-Induced Dormancy in Plasmodium falciparum: Duration, Recovery Rates, and Implications in Treatment Failure
F Teuscher, ML Gatton, N Chen, J Peters, DE Kyle, Q Cheng
The Journal of infectious diseases 202 (9), 1362-1368, 2010
2922010
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium
MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ...
Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014
2842014
The epidemiology of malaria in a Karen population on the western border of Thailand
C Luxemburger, KL Thwai, NJ White, HK Webster, DE Kyle, L Maelankirri, ...
Transactions of the Royal Society of Tropical Medicine and Hygiene 90 (2 …, 1996
2801996
Quinolone-3-diarylethers: a new class of antimalarial drug
A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ...
Science translational medicine 5 (177), 177ra37-177ra37, 2013
2552013
Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I
R McLeod, SP Muench, JB Rafferty, DE Kyle, EJ Mui, MJ Kirisits, DG Mack, ...
International journal for parasitology 31 (2), 109-113, 2001
2552001
Randomised double-blind placebo-controlled trial of SPf66 malaria vaccine in children in northwestern Thailand
F Nosten, C Luxemburger, DE Kyle, WR Ballou, J Wittes, EH Wah, ...
The lancet 348 (9029), 701-707, 1996
2381996
Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America
RK Mehlotra, H Fujioka, PD Roepe, O Janneh, LMB Ursos, ...
Proceedings of the National Academy of Sciences 98 (22), 12689-12694, 2001
2362001
The shikimate pathway and its branches in apicomplexan parasites
CW Roberts, F Roberts, RE Lyons, MJ Kirisits, EJ Mui, J Finnerty, ...
The Journal of infectious diseases 185 (Supplement_1), S25-S36, 2002
2332002
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