Steven H. Kleinstein

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Gur YaariYale UniversityAdresse e-mail validée de yale.edu
Jason Anthony Vander HeidenGenentechAdresse e-mail validée de gene.com
Mohamed UdumanDirector, Immuno-Oncology Computational Biology, Dana-Farber Cancer InstituteAdresse e-mail validée de dfci.harvard.edu
Kevin C. O'ConnorProfessor of Neurology and Immunobiology, Yale UniversityAdresse e-mail validée de yale.edu
Susan M. KaechThe Salk Institute for Biological StudiesAdresse e-mail validée de salk.edu
Mark ShlomchikProfessor of Immunology, University of Pittsburgh School of MedicineAdresse e-mail validée de pitt.edu
Kenneth B HoehnGeisel School of Medicine at DartmouthAdresse e-mail validée de dartmouth.edu
Francois VigneaultCSO founder AbVitro, VP Research Juno, research fellow harvard University George Church labAdresse e-mail validée de abvitro.com
David HaflerProfessor of Neurology and Immunobiology, Yale UniversityAdresse e-mail validée de yale.edu
Namita T GuptaYale UniversityAdresse e-mail validée de yale.edu
Robert A. Amezquita, PhDSr Computational ImmunologistAdresse e-mail validée de pfizer.com
Christopher BolenScientist, GenentechAdresse e-mail validée de gene.com
Corey T. WatsonUniversity of Louisville School of MedicineAdresse e-mail validée de louisville.edu
Daniel Gadala-MariaYale UniversityAdresse e-mail validée de yale.edu
Julian Q ZhouWashington University in St LouisAdresse e-mail validée de wustl.edu
Ann HabermanYale UniversityAdresse e-mail validée de yale.edu
Ruth R MontgomeryProfessor, Yale School of MedicineAdresse e-mail validée de yale.edu
Uri HershbergUniversity of Haifa, Facuty of SciencesAdresse e-mail validée de sci.haifa.ac.il
Stuart SealfonIcahn School of Medicine at Mount SinaiAdresse e-mail validée de mssm.edu
Joel N.H. SternProfessor of Neurology, Urology, Molecular Medicine, and Science EducationAdresse e-mail validée de northwell.edu

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Steven H. Kleinstein

Professor, Departments of Pathology and Immunobiology, Yale School of Medicine

Adresse e-mail validée de yale.edu - Page d'accueil

Computational Immunology Systems Immunology Systems Biology Bioinformatics B cell Repertoire Sequencing: AIRR-seq or Rep-seq


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ... Cell 162 (6), 1217-1228, 2015	1388	2015
Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data NT Gupta, JA Vander Heiden, M Uduman, D Gadala-Maria, G Yaari, ... Bioinformatics 31 (20), 3356-3358, 2015	793	2015
Two levels of protection for the B cell genome during somatic hypermutation M Liu, JL Duke, DJ Richter, CG Vinuesa, CC Goodnow, SH Kleinstein, ... Nature 451 (7180), 841-845, 2008	702	2008
Germinal center B cell and T follicular helper cell development initiates in the interfollicular zone SM Kerfoot, G Yaari, JR Patel, KL Johnson, DG Gonzalez, SH Kleinstein, ... Immunity 34 (6), 947-960, 2011	583	2011
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes JNH Stern, G Yaari, JA Vander Heiden, G Church, WF Donahue, ... Science translational medicine 6 (248), 248ra107-248ra107, 2014	491	2014
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires JA Vander Heiden, G Yaari, M Uduman, JNH Stern, KC O’connor, ... Bioinformatics 30 (13), 1930-1932, 2014	478	2014
CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype GV Zuccarino-Catania, S Sadanand, FJ Weisel, MM Tomayko, H Meng, ... Nature immunology 15 (7), 631-637, 2014	470	2014
Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns AE Hauser, T Junt, TR Mempel, MW Sneddon, SH Kleinstein, ... Immunity 26 (5), 655-667, 2007	378	2007
Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4+ cell properties during viral infection HD Marshall, A Chandele, YW Jung, H Meng, AC Poholek, IA Parish, ... Immunity 35 (4), 633-646, 2011	357	2011
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders S Brioschi, WL Wang, V Peng, M Wang, I Shchukina, ZJ Greenberg, ... Science 373 (6553), eabf9277, 2021	343	2021
The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection CX Dominguez, RA Amezquita, T Guan, HD Marshall, NS Joshi, ... Journal of Experimental Medicine 212 (12), 2041-2056, 2015	277	2015
Practical guidelines for B-cell receptor repertoire sequencing analysis G Yaari, SH Kleinstein Genome medicine 7, 1-14, 2015	274	2015
Human germinal centres engage memory and naive B cells after influenza vaccination JS Turner, JQ Zhou, J Han, AJ Schmitz, AA Rizk, WB Alsoussi, T Lei, ... Nature 586 (7827), 127-132, 2020	272	2020
Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity K Bryniarski, W Ptak, A Jayakumar, K Püllmann, MJ Caplan, ... Journal of Allergy and Clinical Immunology 132 (1), 170-181. e9, 2013	262	2013
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ... Frontiers in immunology 4, 358, 2013	260	2013
Salmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells VM Bruno, S Hannemann, M Lara-Tejero, RA Flavell, SH Kleinstein, ... PLoS pathogens 5 (8), e1000538, 2009	251	2009
Polycomb repressive complex 2-mediated chromatin repression guides effector CD8+ T cell terminal differentiation and loss of multipotency SM Gray, RA Amezquita, T Guan, SH Kleinstein, SM Kaech Immunity 46 (4), 596-608, 2017	248	2017
Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children A Ramaswamy, NN Brodsky, TS Sumida, M Comi, H Asashima, ... Immunity 54 (5), 1083-1095. e7, 2021	245	2021
Salmonella infection drives promiscuous B cell activation followed by extrafollicular affinity maturation R Di Niro, SJ Lee, JA Vander Heiden, RA Elsner, N Trivedi, JM Bannock, ... Immunity 43 (1), 120-131, 2015	235	2015
Dynamic expression profiling of type I and type III interferon‐stimulated hepatocytes reveals a stable hierarchy of gene expression CR Bolen, S Ding, MD Robek, SH Kleinstein Hepatology 59 (4), 1262-1272, 2014	234	2014

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