Genetics of gene expression surveyed in maize, mouse and man EE Schadt, SA Monks, TA Drake, AJ Lusis, N Che, V Colinayo, TG Ruff, ... Nature 422 (6929), 297-302, 2003 | 1914 | 2003 |
Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer’s disease B Zhang, C Gaiteri, LG Bodea, Z Wang, J McElwee, AA Podtelezhnikov, ... Cell 153 (3), 707-720, 2013 | 1800 | 2013 |
Genetics of gene expression and its effect on disease V Emilsson, G Thorleifsson, B Zhang, AS Leonardson, F Zink, J Zhu, ... Nature 452 (7186), 423-428, 2008 | 1617 | 2008 |
An integrative genomics approach to infer causal associations between gene expression and disease EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ... Nature genetics 37 (7), 710-717, 2005 | 1244 | 2005 |
Mapping the genetic architecture of gene expression in human liver EE Schadt, C Molony, E Chudin, K Hao, X Yang, PY Lum, A Kasarskis, ... PLoS biology 6 (5), e107, 2008 | 1204 | 2008 |
Variations in DNA elucidate molecular networks that cause disease Y Chen, J Zhu, PY Lum, X Yang, S Pinto, DJ MacNeil, C Zhang, J Lamb, ... Nature 452 (7186), 429-435, 2008 | 1079 | 2008 |
Tetratrico peptide repeat interactions: to TPR or not to TPR? JR Lamb, S Tugendreich, P Hieter Trends in biochemical sciences 20 (7), 257-259, 1995 | 846 | 1995 |
Overexpression of a kinase‐inactive ATR protein causes sensitivity to DNA‐damaging agents and defects in cell cycle checkpoints WA Cliby, CJ Roberts, KA Cimprich, CM Stringer, JR Lamb, SL Schreiber, ... The EMBO journal, 1998 | 667 | 1998 |
Co-regulatory networks of human serum proteins link genetics to disease V Emilsson, M Ilkov, JR Lamb, N Finkel, EF Gudmundsson, R Pitts, ... Science 361 (6404), 769-773, 2018 | 506 | 2018 |
Specific complex formation between yeast RAD6 and RAD18 proteins: a potential mechanism for targeting RAD6 ubiquitin-conjugating activity to DNA damage sites. V Bailly, J Lamb, P Sung, S Prakash, L Prakash Genes & development 8 (7), 811-820, 1994 | 389 | 1994 |
Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks X Yang, JL Deignan, H Qi, J Zhu, S Qian, J Zhong, G Torosyan, S Majid, ... Nature genetics 41 (4), 415-423, 2009 | 328 | 2009 |
Cdc16p, Cdc23p and Cdc27p form a complex essential for mitosis. JR Lamb, WA Michaud, RS Sikorski, PA Hieter The EMBO journal 13 (18), 4321-4328, 1994 | 315 | 1994 |
Diet induction of monocyte chemoattractant protein‐1 and its impact on obesity A Chen, S Mumick, C Zhang, J Lamb, H Dai, D Weingarth, J Mudgett, ... Obesity research 13 (8), 1311-1320, 2005 | 310 | 2005 |
A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients H Dai, L van't Veer, J Lamb, YD He, M Mao, BM Fine, R Bernards, ... Cancer research 65 (10), 4059-4066, 2005 | 298 | 2005 |
An integrative genomics approach to the reconstruction of gene networks in segregating populations J Zhu, PY Lum, J Lamb, D GuhaThakurta, SW Edwards, R Thieringer, ... Cytogenetic and genome research 105 (2-4), 363-374, 2004 | 289 | 2004 |
In vivo discovery of immunotherapy targets in the tumour microenvironment P Zhou, DR Shaffer, DA Alvarez Arias, Y Nakazaki, W Pos, AJ Torres, ... Nature 506 (7486), 52-57, 2014 | 273 | 2014 |
DisProt: intrinsic protein disorder annotation in 2020 A Hatos, B Hajdu-Soltész, AM Monzon, N Palopoli, L Álvarez, ... Nucleic acids research 48 (D1), D269-D276, 2020 | 255 | 2020 |
Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits M Mehrabian, H Allayee, J Stockton, PY Lum, TA Drake, LW Castellani, ... Nature genetics 37 (11), 1224-1233, 2005 | 245 | 2005 |
microRNA‐122 as a regulator of mitochondrial metabolic gene network in hepatocellular carcinoma J Burchard, C Zhang, AM Liu, RTP Poon, NPY Lee, KF Wong, PC Sham, ... Molecular systems biology 6 (1), 402, 2010 | 244 | 2010 |
Inhibition of DYRK1A and GSK3B induces human β-cell proliferation W Shen, B Taylor, Q Jin, V Nguyen-Tran, S Meeusen, YQ Zhang, ... Nature communications 6 (1), 8372, 2015 | 233 | 2015 |