| The calcium store sensor, STIM1, reciprocally controls Orai and CaV1. 2 channels Y Wang, X Deng, S Mancarella, E Hendron, S Eguchi, J Soboloff, ... Science 330 (6000), 105-109, 2010 | 405 | 2010 |
| S-glutathionylation activates STIM1 and alters mitochondrial homeostasis BJ Hawkins, KM Irrinki, K Mallilankaraman, YC Lien, Y Wang, ... Journal of Cell Biology 190 (3), 391-405, 2010 | 267 | 2010 |
| Near-infrared photoactivatable control of Ca2+ signaling and optogenetic immunomodulation L He, Y Zhang, G Ma, P Tan, Z Li, S Zang, X Wu, J Jing, S Fang, L Zhou, ... elife 4, e10024, 2015 | 245 | 2015 |
| Proteomic mapping of ER–PM junctions identifies STIMATE as a regulator of Ca2+ influx J Jing, L He, A Sun, A Quintana, Y Ding, G Ma, P Tan, X Liang, X Zheng, ... Nature cell biology 17 (10), 1339-1347, 2015 | 238 | 2015 |
| Inside-out Ca2+ signalling prompted by STIM1 conformational switch G Ma, M Wei, L He, C Liu, B Wu, SL Zhang, J Jing, X Liang, A Senes, ... Nature communications 6 (1), 1-14, 2015 | 201 | 2015 |
| Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site X Wang, Y Wang, Y Zhou, E Hendron, S Mancarella, MD Andrake, ... Biophysical Journal 106 (2), 314a, 2014 | 190 | 2014 |
| The SOS2-SCaBP8 complex generates and fine-tunes an AtANN4-dependent calcium signature under salt stress L Ma, J Ye, Y Yang, H Lin, L Yue, J Luo, YU Long, H Fu, X Liu, Y Zhang, ... Developmental Cell 48 (5), 697-709. e5, 2019 | 172 | 2019 |
| STIM protein coupling in the activation of Orai channels Y Wang, X Deng, Y Zhou, E Hendron, S Mancarella, MF Ritchie, XD Tang, ... Proceedings of the National Academy of Sciences 106 (18), 7391-7396, 2009 | 168 | 2009 |
| STIM and Orai: dynamic intermembrane coupling to control cellular calcium signals X Deng, Y Wang, Y Zhou, J Soboloff, DL Gill Journal of Biological Chemistry 284 (34), 22501-22505, 2009 | 156 | 2009 |
| The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels Y Zhou, S Mancarella, Y Wang, C Yue, M Ritchie, DL Gill, J Soboloff Journal of Biological Chemistry 284 (29), 19164-19168, 2009 | 147 | 2009 |
| Stim, ORAI and TRPC channels in the control of calcium entry signals in smooth muscle Y Wang, X Deng, T Hewavitharana, J Soboloff, DL Gill Clinical and experimental pharmacology & physiology 35 (9), 1127, 2008 | 143 | 2008 |
| The Orai1 Store-Operated Calcium Channel Functions as a Hexamer*♦ X Cai, Y Zhou, RM Nwokonko, NA Loktionova, X Wang, P Xin, M Trebak, ... Journal of Biological Chemistry 291 (50), 25764-25775, 2016 | 130 | 2016 |
| Targeting calcium signaling induces epigenetic reactivation of tumor suppressor genes in cancer NJM Raynal, JT Lee, Y Wang, A Beaudry, P Madireddi, J Garriga, ... Cancer research 76 (6), 1494-1505, 2016 | 109 | 2016 |
| The STIM1-binding site nexus remotely controls Orai1 channel gating Y Zhou, X Cai, NA Loktionova, X Wang, RM Nwokonko, X Wang, Y Wang, ... Nature communications 7 (1), 13725, 2016 | 105 | 2016 |
| Calcium signaling by STIM and Orai: intimate coupling details revealed Y Wang, X Deng, DL Gill Science signaling 3 (148), pe42-pe42, 2010 | 96 | 2010 |
| STIM1 dimers undergo unimolecular coupling to activate Orai1 channels Y Zhou, X Wang, X Wang, NA Loktionova, X Cai, RM Nwokonko, E Vrana, ... Nature communications 6 (1), 8395, 2015 | 90 | 2015 |
| The STIM-Orai coupling interface and gating of the Orai1 channel Y Zhou, X Cai, RM Nwokonko, NA Loktionova, Y Wang, DL Gill Cell calcium 63, 8-13, 2017 | 89 | 2017 |
| Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle S Mancarella, S Potireddy, Y Wang, H Gao, RK Gandhirajan, M Autieri, ... The FASEB Journal 27 (3), 893, 2013 | 88 | 2013 |
| Cross-linking of Orai1 channels by STIM proteins Y Zhou, RM Nwokonko, X Cai, NA Loktionova, R Abdulqadir, P Xin, ... Proceedings of the National Academy of Sciences 115 (15), E3398-E3407, 2018 | 85 | 2018 |
| Orai channel pore properties and gating by STIM: implications from the Orai crystal structure BS Rothberg, Y Wang, DL Gill Science signaling 6 (267), pe9-pe9, 2013 | 81 | 2013 |
yandong zhouPenn State University College of MedicineAdresse e-mail validée de psu.edu