Suivre
Kevin G. Hoff
Kevin G. Hoff
Sr. Director, Protein Engineerin & Oprtimization
Adresse e-mail validée de metagenomi.co
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Année
Transfer of sulfur from IscS to IscU during Fe/S cluster assembly
HD Urbina, JJ Silberg, KG Hoff, LE Vickery
Journal of Biological Chemistry 276 (48), 44521-44526, 2001
3372001
Reprogramming cellular behavior with RNA controllers responsive to endogenous proteins
SJ Culler, KG Hoff, CD Smolke
Science 330 (6008), 1251-1255, 2010
3212010
Interaction of the iron–sulfur cluster assembly protein IscU with the Hsc66/Hsc20 molecular chaperone system of Escherichia coli
KG Hoff, JJ Silberg, LE Vickery
Proceedings of the National Academy of Sciences 97 (14), 7790-7795, 2000
2792000
Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly
SA Garland, K Hoff, LE Vickery, VC Culotta
Journal of molecular biology 294 (4), 897-907, 1999
2271999
Insights into the sirtuin mechanism from ternary complexes containing NAD+ and acetylated peptide
KG Hoff, JL Avalos, K Sens, C Wolberger
Structure 14 (8), 1231-1240, 2006
1782006
Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase
A Hinman, CR Holst, JC Latham, JJ Bruegger, G Ulas, KP McCusker, ...
PLoS one 13 (8), e0201369, 2018
1622018
Model‐guided design of ligand‐regulated RNAi for programmable control of gene expression
CL Beisel, TS Bayer, KG Hoff, CD Smolke
Molecular systems biology 4 (1), 224, 2008
1542008
Jac1, a mitochondrial J-type chaperone, is involved in the biogenesis of Fe/S clusters in Saccharomyces cerevisiae
C Voisine, YC Cheng, M Ohlson, B Schilke, K Hoff, H Beinert, J Marszalek, ...
Proceedings of the National Academy of Sciences 98 (4), 1483-1488, 2001
1532001
Structural insights into intermediate steps in the Sir2 deacetylation reaction
WF Hawse, KG Hoff, DG Fatkins, A Daines, OV Zubkova, VL Schramm, ...
Structure 16 (9), 1368-1377, 2008
1442008
Hsc66 substrate specificity is directed toward a discrete region of the iron-sulfur cluster template protein IscU
KG Hoff, DT Ta, TL Tapley, JJ Silberg, LE Vickery
Journal of Biological Chemistry 277 (30), 27353-27359, 2002
1432002
Design of small molecule-responsive microRNAs based on structural requirements for Drosha processing
CL Beisel, YY Chen, SJ Culler, KG Hoff, CD Smolke
Nucleic acids research 39 (7), 2981-2994, 2011
1282011
The Fe/S assembly protein IscU behaves as a substrate for the molecular chaperone Hsc66 from Escherichia coli
JJ Silberg, KG Hoff, TL Tapley, LE Vickery
Journal of Biological Chemistry 276 (3), 1696-1700, 2001
1242001
The Hsc66-Hsc20 Chaperone System inEscherichia coli: Chaperone Activity and Interactions with the DnaK-DnaJ-GrpE System
JJ Silberg, KG Hoff, LE Vickery
Journal of bacteriology 180 (24), 6617-6624, 1998
1141998
Regulation of the HscA ATPase reaction cycle by the co-chaperone HscB and the iron-sulfur cluster assembly protein IscU
JJ Silberg, TL Tapley, KG Hoff, LE Vickery
Journal of Biological Chemistry 279 (52), 53924-53931, 2004
1132004
Contributions of the LPPVK motif of the iron-sulfur template protein IscU to interactions with the Hsc66-Hsc20 chaperone system
KG Hoff, JR Cupp-Vickery, LE Vickery
Journal of Biological Chemistry 278 (39), 37582-37589, 2003
812003
Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy
AH Kahn-Kirby, A Amagata, CI Maeder, JJ Mei, S Sideris, Y Kosaka, ...
PLoS One 14 (3), e0214250, 2019
702019
Tal-effector assembly platform, customized services, kits and assays
F Katzen, J Chesnut, F Notka, M Arnold, K Hoff, S Whiteside
US Patent App. 13/856,978, 2013
702013
In vivo fluorescent detection of Fe-S clusters coordinated by human GRX2
KG Hoff, SJ Culler, PQ Nguyen, RM McGuire, JJ Silberg, CD Smolke
Chemistry & biology 16 (12), 1299-1308, 2009
462009
A genetically encoded and gate for cell-targeted metabolic labeling of proteins
A Mahdavi, TH Segall-Shapiro, S Kou, GA Jindal, KG Hoff, S Liu, ...
Journal of the American Chemical Society 135 (8), 2979-2982, 2013
392013
Functional selection and systematic analysis of intronic splicing elements identify active sequence motifs and associated splicing factors
SJ Culler, KG Hoff, RB Voelker, JA Berglund, CD Smolke
Nucleic acids research 38 (15), 5152-5165, 2010
392010
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