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Murphy
Murphy
Biology, Zoology
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Structure and function of matrix metalloproteinases and TIMPs
H Nagase, R Visse, G Murphy
Cardiovascular research 69 (3), 562-573, 2006
44342006
Metalloproteinase inhibitors: biological actions and therapeutic opportunities
AH Baker, DR Edwards, G Murphy
Journal of cell science 115 (19), 3719-3727, 2002
17462002
Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.
DR Edwards, G Murphy, JJ Reynolds, SE Whitham, AJ Docherty, P Angel, ...
The EMBO journal 6 (7), 1899-1904, 1987
15811987
Analysis of the acute and chronic wound environments: the role of proteases and their inhibitors
NJ Trengove, MC Stacey, S Macauley, N Bennett, J Gibson, F Burslem, ...
Wound Repair and Regeneration 7 (6), 442-452, 1999
11921999
Biochemical characterization of human collagenase-3
V Knäuper, C López-Otin, B Smith, G Knight, G Murphy
Journal of Biological Chemistry 271 (3), 1544-1550, 1996
11731996
Progress in matrix metalloproteinase research
G Murphy, H Nagase
Molecular aspects of medicine 29 (5), 290-308, 2008
10362008
Cellular mechanisms for human procollagenase-3 (MMP-13) activation: evidence that MT1-MMP (MMP-14) and gelatinase A (MMP-2) are able to generate active enzyme
V Knäuper, H Will, C López-Otin, B Smith, SJ Atkinson, H Stanton, ...
Journal of Biological Chemistry 271 (29), 17124-17131, 1996
9111996
Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity
AJP Docherty, A Lyons, BJ Smith, EM Wright, PE Stephens, TJR Harris, ...
Nature 318 (6041), 66-69, 1985
8701985
A novel coumarin-labelled peptide for sensitive continuous assays of the matrix metalloproteinases
CG Knight, F Willenbrock, G Murphy
FEBS letters 296 (3), 263-266, 1992
8641992
Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization.
AM Henney, PR Wakeley, MJ Davies, K Foster, R Hembry, G Murphy, ...
Proceedings of the National Academy of Sciences 88 (18), 8154-8158, 1991
8381991
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2
JH Qi, Q Ebrahem, N Moore, G Murphy, L Claesson-Welsh, M Bond, ...
Nature medicine 9 (4), 407-415, 2003
8312003
TNF-α converting enzyme (TACE) is inhibited by TIMP-3
A Amour, PM Slocombe, A Webster, M Butler, CG Knight, BJ Smith, ...
FEBS letters 435 (1), 39-44, 1998
8301998
Tumor necrosis factor-α-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)
KJ Garton, PJ Gough, CP Blobel, G Murphy, DR Greaves, PJ Dempsey, ...
Journal of Biological Chemistry 276 (41), 37993-38001, 2001
8082001
The matrix metalloproteinases and their inhibitors
G Murphy, AJP Docherty
American journal of respiratory cell and molecular biology 7, 120-120, 1992
7981992
The TIMP2 membrane type 1 metalloproteinase “receptor” regulates the concentration and efficient activation of progelatinase A: a kinetic study
GS Butler, MJ Butler, SJ Atkinson, H Will, T Tamura, SS van Westrum, ...
Journal of Biological Chemistry 273 (2), 871-880, 1998
7671998
The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation: regulation by TIMP …
H Will, SJ Atkinson, GS Butler, B Smith, G Murphy
Journal of Biological Chemistry 271 (29), 17119-17123, 1996
7151996
The ADAMs: signalling scissors in the tumour microenvironment
G Murphy
Nature Reviews Cancer 8 (12), 932-941, 2008
6602008
Plasmin and matrix metalloproteinases in vascular remodeling
HR Lijnen
Thrombosis and haemostasis 86 (07), 324-333, 2001
6442001
Stromelysin, a connective tissue-degrading metalloendopeptidase secreted by stimulated rabbit synovial fibroblasts in parallel with collagenase. Biosynthesis, isolation …
JR Chin, G Murphy, Z Werb
Journal of Biological Chemistry 260 (22), 12367-12376, 1985
6251985
Mechanisms for pro matrix metalloproteinase activation
G Murphy, H Stanton, S Cowell, G Butler, V KNÄUPER, S ATKINSON, ...
Apmis 107 (1‐6), 38-44, 1999
6121999
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