Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3498 | 2017 |
The GTEx Consortium atlas of genetic regulatory effects across human tissues GTEx Consortium Science 369 (6509), 1318-1330, 2020 | 3071 | 2020 |
Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants BL Pierce, H Ahsan, TJ VanderWeele International journal of epidemiology 40 (3), 740-752, 2011 | 1253 | 2011 |
Efficient design for Mendelian randomization studies: subsample and 2-sample instrumental variable estimators BL Pierce, S Burgess American journal of epidemiology 178 (7), 1177-1184, 2013 | 1123 | 2013 |
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... Nature genetics 53 (9), 1300-1310, 2021 | 1049 | 2021 |
Arsenic exposure from drinking water, and all-cause and chronic-disease mortalities in Bangladesh (HEALS): a prospective cohort study M Argos, T Kalra, PJ Rathouz, Y Chen, B Pierce, F Parvez, T Islam, ... The Lancet 376 (9737), 252-258, 2010 | 858 | 2010 |
Elevated biomarkers of inflammation are associated with reduced survival among breast cancer patients BL Pierce, R Ballard-Barbash, L Bernstein, RN Baumgartner, ... Journal of Clinical Oncology 27 (21), 3437-3444, 2009 | 827 | 2009 |
The impact of sex on gene expression across human tissues M Oliva, M Muñoz-Aguirre, S Kim-Hellmuth, V Wucher, ADH Gewirtz, ... Science 369 (6509), eaba3066, 2020 | 805 | 2020 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 658 | 2019 |
Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 583 | 2017 |
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis U Võsa, A Claringbould, HJ Westra, MJ Bonder, P Deelen, B Zeng, ... BioRxiv, 447367, 2018 | 511 | 2018 |
Determinants of telomere length across human tissues K Demanelis, F Jasmine, LS Chen, M Chernoff, L Tong, D Delgado, ... Science 369 (6509), eaaz6876, 2020 | 392 | 2020 |
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood T Qi, Y Wu, J Zeng, F Zhang, A Xue, L Jiang, Z Zhu, K Kemper, L Yengo, ... Nature communications 9 (1), 2282, 2018 | 355 | 2018 |
A quantitative proteome map of the human body L Jiang, M Wang, S Lin, R Jian, X Li, J Chan, G Dong, H Fang, ... Cell 183 (1), 269-283. e19, 2020 | 347 | 2020 |
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits E Porcu, S Rüeger, K Lepik, FA Santoni, A Reymond, Z Kutalik Nature communications 10 (1), 3300, 2019 | 263 | 2019 |
Genome-wide association study identifies chromosome 10q24. 32 variants associated with arsenic metabolism and toxicity phenotypes in Bangladesh BL Pierce, MG Kibriya, L Tong, F Jasmine, M Argos, S Roy, R Paul-Brutus, ... PLoS genetics 8 (2), e1002522, 2012 | 198 | 2012 |
Drinking water arsenic contamination, skin lesions, and malignancies: a systematic review of the global evidence MR Karagas, A Gossai, B Pierce, H Ahsan Current environmental health reports 2, 52-68, 2015 | 195 | 2015 |
Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study VI Dimitrakopoulou, KK Tsilidis, PC Haycock, NL Dimou, K Al-Dabhani, ... bmj 359, 2017 | 190 | 2017 |
Co-expression networks reveal the tissue-specific regulation of transcription and splicing A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ... Genome research 27 (11), 1843-1858, 2017 | 180 | 2017 |
A prospective study of arsenic exposure from drinking water and incidence of skin lesions in Bangladesh M Argos, T Kalra, BL Pierce, Y Chen, F Parvez, T Islam, A Ahmed, ... American journal of epidemiology 174 (2), 185-194, 2011 | 171 | 2011 |