STIM proteins: dynamic calcium signal transducers J Soboloff, BS Rothberg, M Madesh, DL Gill Nature reviews Molecular cell biology 13 (9), 549-565, 2012 | 788 | 2012 |
MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca2+ uptake that regulates cell survival K Mallilankaraman, P Doonan, C Cárdenas, HC Chandramoorthy, ... Cell 151 (3), 630-644, 2012 | 697 | 2012 |
Blocker state dependence and trapping in hyperpolarization-activated cation channels: evidence for an intracellular activation gate KS Shin, BS Rothberg, G Yellen The Journal of general physiology 117 (2), 91-102, 2001 | 226 | 2001 |
Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site X Wang, Y Wang, Y Zhou, E Hendron, S Mancarella, MD Andrake, ... Biophysical Journal 106 (2), 314a, 2014 | 190 | 2014 |
Voltage and Ca2+ Activation of Single Large-Conductance Ca2+-Activated K+ Channels Described by a Two-Tiered Allosteric Gating Mechanism BS Rothberg, KL Magleby The Journal of general physiology 116 (1), 75-100, 2000 | 185 | 2000 |
Gating Kinetics of Single Large-Conductance Ca2+-Activated K+ Channels in High Ca2+ Suggest a Two-Tiered Allosteric Gating Mechanism✪ BS Rothberg, KL Magleby The Journal of general physiology 114 (1), 93-124, 1999 | 158 | 1999 |
Mechanism of β4 subunit modulation of BK channels B Wang, BS Rothberg, R Brenner The Journal of general physiology 127 (4), 449-465, 2006 | 138 | 2006 |
Voltage-controlled gating at the intracellular entrance to a hyperpolarization-activated cation channel BS Rothberg, KS Shin, PS Phale, G Yellen The Journal of general physiology 119 (1), 83-91, 2002 | 131 | 2002 |
Inactivation in HCN channels results from reclosure of the activation gate: desensitization to voltage KS Shin, C Maertens, C Proenza, BS Rothberg, G Yellen Neuron 41 (5), 737-744, 2004 | 129 | 2004 |
Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling W Kopec, BS Rothberg, BL de Groot Nature communications 10 (1), 5366, 2019 | 108 | 2019 |
The STIM1-binding site nexus remotely controls Orai1 channel gating Y Zhou, X Cai, NA Loktionova, X Wang, RM Nwokonko, X Wang, Y Wang, ... Nature communications 7 (1), 13725, 2016 | 105 | 2016 |
STIM1 dimers undergo unimolecular coupling to activate Orai1 channels Y Zhou, X Wang, X Wang, NA Loktionova, X Cai, RM Nwokonko, E Vrana, ... Nature communications 6 (1), 8395, 2015 | 90 | 2015 |
Mechanism of increased BK channel activation from a channel mutation that causes epilepsy B Wang, BS Rothberg, R Brenner Biophysical Journal 96 (3), 381a, 2009 | 90 | 2009 |
Orai channel pore properties and gating by STIM: implications from the Orai crystal structure BS Rothberg, Y Wang, DL Gill Science signaling 6 (267), pe9-pe9, 2013 | 81 | 2013 |
A role for the S0 transmembrane segment in voltage-dependent gating of BK channels OM Koval, Y Fan, BS Rothberg The Journal of general physiology 129 (3), 209-220, 2007 | 74 | 2007 |
Kinetic Structure of Large-Conductance Ca2+-activated K+ Channels Suggests that the Gating Includes Transitions through Intermediate or Secondary States: A … BS Rothberg, KL Magleby The Journal of general physiology 111 (6), 751-780, 1998 | 72 | 1998 |
Movements near the gate of a hyperpolarization-activated cation channel BS Rothberg, KS Shin, G Yellen The Journal of general physiology 122 (5), 501-510, 2003 | 64 | 2003 |
The BK channel: a vital link between cellular calcium and electrical signaling BS Rothberg Protein & cell 3, 883-892, 2012 | 53 | 2012 |
Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain VPT Pau, FJ Smith, AB Taylor, LV Parfenova, E Samakai, MM Callaghan, ... Proceedings of the National Academy of Sciences 108 (43), 17684-17689, 2011 | 46 | 2011 |
High Ca2+ concentrations induce a low activity mode and reveal Ca2 (+)‐independent long shut intervals in BK channels from rat muscle. BS Rothberg, RA Bello, L Song, KL Magleby The Journal of physiology 493 (3), 673-689, 1996 | 45 | 1996 |