| Computational design of high-affinity epitope scaffolds by backbone grafting of a linear epitope ML Azoitei, YEA Ban, JP Julien, S Bryson, A Schroeter, O Kalyuzhniy, ... Journal of molecular biology 415 (1), 175-192, 2012 | 114 | 2012 |
| Choice of adaptive sampling strategy impacts state discovery, transition probabilities, and the apparent mechanism of conformational changes MI Zimmerman, JR Porter, X Sun, RR Silva, GR Bowman Journal of chemical theory and computation 14 (11), 5459-5475, 2018 | 83 | 2018 |
| Electron cryo-microscopy structure of Ebola virus nucleoprotein reveals a mechanism for nucleocapsid-like assembly Z Su, C Wu, L Shi, P Luthra, GD Pintilie, B Johnson, JR Porter, P Ge, ... Cell 172 (5), 966-978. e12, 2018 | 63 | 2018 |
| Cooperative changes in solvent exposure identify cryptic pockets, switches, and allosteric coupling JR Porter, KE Moeder, CA Sibbald, MI Zimmerman, KM Hart, ... Biophysical Journal 116 (5), 818-830, 2019 | 62 | 2019 |
| Enspara: Modeling molecular ensembles with scalable data structures and parallel computing JR Porter, MI Zimmerman, GR Bowman The Journal of chemical physics 150 (4), 2019 | 53 | 2019 |
| Access to Cα Backbone Dynamics of Biological Solids by 13C T1 Relaxation and Molecular Dynamics Simulation S Asami, JR Porter, OF Lange, B Reif Journal of the American Chemical Society 137 (3), 1094-1100, 2015 | 33 | 2015 |
| Conformational distributions of isolated myosin motor domains encode their mechanochemical properties JR Porter, A Meller, MI Zimmerman, MJ Greenberg, GR Bowman Elife 9, e55132, 2020 | 32 | 2020 |
| SARS-CoV-2 simulations go exascale to capture spike opening and reveal cryptic pockets across the proteome MI Zimmerman, JR Porter, MD Ward, S Singh, N Vithani, A Meller, ... BioRxiv, 2020.06. 27.175430, 2020 | 29 | 2020 |
| Robust and highly accurate automatic NOESY assignment and structure determination with Rosetta Z Zhang, J Porter, K Tripsianes, OF Lange Journal of biomolecular NMR 59, 135-145, 2014 | 29 | 2014 |
| Computational design of protein antigens that interact with the CDR H3 loop of HIV broadly neutralizing antibody 2F5 ML Azoitei, YA Ban, O Kalyuzhny, J Guenaga, A Schroeter, J Porter, ... Proteins: Structure, Function, and Bioinformatics 82 (10), 2770-2782, 2014 | 21 | 2014 |
| Extending RosettaDock with water, sugar, and pH for prediction of complex structures and affinities for CAPRI rounds 20–27 KP Kilambi, MS Pacella, J Xu, JW Labonte, JR Porter, P Muthu, K Drew, ... Proteins: Structure, Function, and Bioinformatics 81 (12), 2201-2209, 2013 | 21 | 2013 |
| Site-specific analysis of heteronuclear Overhauser effects in microcrystalline proteins JML Amo, V Agarwal, R Sarkar, J Porter, S Asami, M Rübbelke, U Fink, ... Journal of biomolecular NMR 59, 241-249, 2014 | 20 | 2014 |
| Antagonism between substitutions in β-lactamase explains a path not taken in the evolution of bacterial drug resistance CA Brown, L Hu, Z Sun, MP Patel, S Singh, JR Porter, B Sankaran, ... Journal of Biological Chemistry 295 (21), 7376-7390, 2020 | 19 | 2020 |
| A framework to simplify combined sampling strategies in Rosetta JR Porter, BD Weitzner, OF Lange PLOS one 10 (9), e0138220, 2015 | 15 | 2015 |
| Discovery of a cryptic allosteric site in Ebola’s ‘undruggable’VP35 protein using simulations and experiments MA Cruz, TE Frederick, S Singh, N Vithani, MI Zimmerman, JR Porter, ... BioRxiv 17, 2020.02. 09.940510, 2020 | 12 | 2020 |
| Naturally occurring genetic variants in the oxytocin receptor alter receptor signaling profiles M Malik, MD Ward, Y Fang, JR Porter, MI Zimmerman, T Koelblen, M Roh, ... ACS Pharmacology & Translational Science 4 (5), 1543-1555, 2021 | 9 | 2021 |
| Human PLCG2 Haploinsufficiency Results in a Novel NK Cell Immunodeficiency JB Alinger, EM Mace, JR Porter, AY Mah-Som, AL Daugherty, S Li, ... Journal of Allergy and Clinical Immunology, 2023 | 8 | 2023 |
| Electron cryo-microscopy structure of Ebola nucleoprotein reveals a mechanism for nucleocapsid-like assembly Z Su, C Wu, L Shi, P Luthra, GD Pintilie, B Johnson, JR Porter, P Ge, ... | | |
Gregory R. BowmanProfessor, University of PennsylvaniaAdresse e-mail validée de seas.upenn.edu
