Zika viral dynamics and shedding in rhesus and cynomolgus macaques CE Osuna, SY Lim, C Deleage, BD Griffin, D Stein, LT Schroeder, ... Nature medicine 22 (12), 1448, 2016 | 330 | 2016 |
Zika virus persistence in the central nervous system and lymph nodes of rhesus monkeys M Aid, P Abbink, RA Larocca, M Boyd, R Nityanandam, O Nanayakkara, ... Cell 169 (4), 610-620. e14, 2017 | 222 | 2017 |
T-cell receptor repertoires share a restricted set of public and abundant CDR3 sequences that are associated with self-related immunity A Madi, E Shifrut, S Reich-Zeliger, H Gal, K Best, W Ndifon, B Chain, ... Genome research 24 (10), 1603-1612, 2014 | 203 | 2014 |
Tracking global changes induced in the CD4 T-cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence N Thomas, K Best, M Cinelli, S Reich-Zeliger, H Gal, E Shifrut, A Madi, ... Bioinformatics 30 (22), 3181-3188, 2014 | 124 | 2014 |
Quantitative characterization of the T cell receptor repertoire of naïve and memory subsets using an integrated experimental and computational pipeline which is robust … T Oakes, JM Heather, K Best, R Byng-Maddick, C Husovsky, M Ismail, ... Frontiers in immunology 8, 1267, 2017 | 116 | 2017 |
Blood transcriptomic diagnosis of pulmonary and extrapulmonary tuberculosis JK Roe, N Thomas, E Gil, K Best, E Tsaliki, S Morris‑Jones, S Stafford, ... JCI insight 1 (16), 2016 | 108 | 2016 |
Computational analysis of stochastic heterogeneity in PCR amplification efficiency revealed by single molecule barcoding K Best, T Oakes, JM Heather, J Shawe-Taylor, B Chain Scientific reports 5 (1), 1-13, 2015 | 103 | 2015 |
Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies K Best, J Guedj, V Madelain, X de Lamballerie, SY Lim, CE Osuna, ... Proceedings of the National Academy of Sciences 114 (33), 8847-8852, 2017 | 102 | 2017 |
Dynamic perturbations of the T-cell receptor repertoire in chronic HIV infection and following antiretroviral therapy JM Heather, K Best, T Oakes, ER Gray, JK Roe, N Thomas, N Friedman, ... Frontiers in immunology 6, 644, 2016 | 86 | 2016 |
Feature selection using a one dimensional naïve Bayes' classifier increases the accuracy of support vector machine classification of CDR3 repertoires. M Cinelli, Y Sun, K Best, JM Heather, S Reich-Zeliger, E Shifrut, ... Bioinformatics 33 (7), 951-955, 2017 | 76 | 2017 |
Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody M Asokan, J Dias, C Liu, A Maximova, K Ernste, A Pegu, K McKee, W Shi, ... Proceedings of the National Academy of Sciences 117 (31), 18754-18763, 2020 | 66 | 2020 |
Mathematical modeling of within‐host Zika virus dynamics K Best, AS Perelson Immunological reviews 285 (1), 81-96, 2018 | 55 | 2018 |
The impact of DAMP-mediated inflammation in severe COVID-19 and related disorders U Parthasarathy, R Martinelli, EH Vollmann, K Best, AG Therien Biochemical Pharmacology 195, 114847, 2022 | 49 | 2022 |
Specificity, privacy, and degeneracy in the CD4 T cell receptor repertoire following immunization Y Sun, K Best, M Cinelli, JM Heather, S Reich-Zeliger, E Shifrut, ... Frontiers in immunology 8, 430, 2017 | 49 | 2017 |
Principles governing establishment versus collapse of HIV-1 cellular spread JM Hataye, JP Casazza, K Best, CJ Liang, TT Immonen, DR Ambrozak, ... Cell host & microbe 26 (6), 748-763. e20, 2019 | 36 | 2019 |
A direct-acting antiviral drug abrogates viremia in Zika virus–infected rhesus macaques SY Lim, CE Osuna, K Best, R Taylor, E Chen, G Yoon, JL Kublin, D Schalk, ... Science translational medicine 12 (547), eaau9135, 2020 | 25 | 2020 |
The T cell response to the contact sensitizer paraphenylenediamine is characterized by a polyclonal diverse repertoire of antigen-specific receptors T Oakes, AL Popple, J Williams, K Best, JM Heather, M Ismail, G Maxwell, ... Frontiers in immunology 8, 162, 2017 | 21 | 2017 |
Transcriptional profiling of endobronchial ultrasound-guided lymph node samples aids diagnosis of mediastinal lymphadenopathy GS Tomlinson, N Thomas, BM Chain, K Best, N Simpson, G Hardavella, ... Chest 149 (2), 535-544, 2016 | 20 | 2016 |
Pericyte derived chemokines amplify neutrophil recruitment across the cerebrovascular endothelial barrier. E Gil, C Venturini, D Stirling, C Turner, LB Tezera, G Ercoli, T Baker, ... Frontiers in immunology, 4149, 2022 | 13 | 2022 |
Zika virus dynamics: Effects of inoculum dose, the innate immune response and viral interference K Best, DH Barouch, J Guedj, RM Ribeiro, AS Perelson PLoS computational biology 17 (1), e1008564, 2021 | 13 | 2021 |