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Amarendra Pegu
Amarendra Pegu
Head, Antibody Research, Virology core, VRC, NIAID, NIH
Adresse e-mail validée de niaid.nih.gov
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Evaluation of the mRNA-1273 vaccine against SARS-CoV-2 in nonhuman primates
KS Corbett, B Flynn, KE Foulds, JR Francica, S Boyoglu-Barnum, ...
New England Journal of Medicine 383 (16), 1544-1555, 2020
12132020
Durability of mRNA-1273 vaccine–induced antibodies against SARS-CoV-2 variants
A Pegu, SE O’Connell, SD Schmidt, S O’Dell, CA Talana, L Lai, J Albert, ...
Science 373 (6561), 1372-1377, 2021
5702021
Infection and vaccine-induced neutralizing-antibody responses to the SARS-CoV-2 B. 1.617 variants
VV Edara, BA Pinsky, MS Suthar, L Lai, ME Davis-Gardner, K Floyd, ...
New England Journal of Medicine 385 (7), 664-666, 2021
4032021
Enhanced neonatal Fc receptor function improves protection against primate SHIV infection
SY Ko, A Pegu, RS Rudicell, Z Yang, MG Joyce, X Chen, K Wang, S Bao, ...
Nature 514 (7524), 642-645, 2014
3882014
A single injection of anti-HIV-1 antibodies protects against repeated SHIV challenges
R Gautam, Y Nishimura, A Pegu, MC Nason, F Klein, A Gazumyan, ...
Nature 533 (7601), 105-109, 2016
3632016
Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques
L Xu, A Pegu, E Rao, N Doria-Rose, J Beninga, K McKee, DM Lord, ...
Science 358 (6359), 85-90, 2017
3252017
Enhanced Potency of a Broadly Neutralizing HIV-1 Antibody In Vitro Improves Protection against Lentiviral Infection In Vivo
RS Rudicell, YD Kwon, SY Ko, A Pegu, MK Louder, IS Georgiev, X Wu, ...
Journal of virology 88 (21), 12669-12682, 2014
3182014
Early Events in Mycobacterium tuberculosis Infection in Cynomolgus Macaques
PL Lin, S Pawar, A Myers, A Pegu, C Fuhrman, TA Reinhart, SV Capuano, ...
Infection and immunity 74 (7), 3790-3803, 2006
2902006
Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults
Clinical & Experimental Immunology 182 (3), 289-301, 2015
2792015
Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor
A Pegu, Z Yang, JC Boyington, L Wu, SY Ko, SD Schmidt, K McKee, ...
Science translational medicine 6 (243), 243ra88-243ra88, 2014
2582014
New member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency
NA Doria-Rose, JN Bhiman, RS Roark, CA Schramm, J Gorman, ...
Journal of virology 90 (1), 76-91, 2016
2552016
Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants
L Wang, T Zhou, Y Zhang, ES Yang, CA Schramm, W Shi, A Pegu, ...
Science 373 (6556), eabh1766, 2021
1982021
Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques
AJ Hessell, JP Jaworski, E Epson, K Matsuda, S Pandey, C Kahl, J Reed, ...
Nature medicine 22 (4), 362-368, 2016
1942016
Follicular CD8 T cells accumulate in HIV infection and can kill infected cells in vitro via bispecific antibodies
C Petrovas, S Ferrando-Martinez, MY Gerner, JP Casazza, A Pegu, ...
Science translational medicine 9 (373), eaag2285, 2017
1672017
Human herpesvirus 8 infects and replicates in primary cultures of activated B lymphocytes through DC-SIGN
G Rappocciolo, HR Hensler, M Jais, TA Reinhart, A Pegu, FJ Jenkins, ...
Journal of virology 82 (10), 4793-4806, 2008
1672008
Use of broadly neutralizing antibodies for HIV‐1 prevention
A Pegu, AJ Hessell, JR Mascola, NL Haigwood
Immunological reviews 275 (1), 296-312, 2017
1652017
Broadly neutralizing antibodies target the coronavirus fusion peptide
C Dacon, C Tucker, L Peng, CCD Lee, TH Lin, M Yuan, Y Cong, L Wang, ...
Science 377 (6607), 728-735, 2022
1642022
Human lymphatic endothelial cells express multiple functional TLRs
A Pegu, S Qin, BA Fallert Junecko, RE Nisato, MS Pepper, TA Reinhart
The Journal of Immunology 180 (5), 3399-3405, 2008
1502008
Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B. 1.1. 529
T Zhou, L Wang, J Misasi, A Pegu, Y Zhang, DR Harris, AS Olia, ...
Science 376 (6591), eabn8897, 2022
1382022
A platform incorporating trimeric antigens into self-assembling nanoparticles reveals SARS-CoV-2-spike nanoparticles to elicit substantially higher neutralizing responses than …
B Zhang, CW Chao, Y Tsybovsky, OM Abiona, GB Hutchinson, JI Moliva, ...
Scientific reports 10 (1), 18149, 2020
1282020
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