Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 6064 | 2018 |
Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27 M Pagano, SW Tam, AM Theodoras, P Beer-Romero, G Del Sal, V Chau, ... Science 269 (5224), 682-685, 1995 | 2314 | 1995 |
Cyclin D1 is a nuclear protein required for cell cycle progression in G1. V Baldin, J Lukas, MJ Marcote, M Pagano, G Draetta Genes & development 7 (5), 812-821, 1993 | 2139 | 1993 |
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27 AC Carrano, E Eytan, A Hershko, M Pagano Nature cell biology 1 (4), 193-199, 1999 | 1939 | 1999 |
Cyclin A is required at two points in the human cell cycle. M Pagano, R Pepperkok, F Verde, W Ansorge, G Draetta The EMBO journal 11 (3), 961-971, 1992 | 1797 | 1992 |
Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex N Zheng, BA Schulman, L Song, JJ Miller, PD Jeffrey, P Wang, C Chu, ... Nature 416 (6882), 703-709, 2002 | 1756 | 2002 |
Human Cyclin E, a Nuclear Protein Essential for the G1-to-S Phase Transition M Ohtsubo, AM Theodoras, J Schumacher, JM Roberts, M Pagano Molecular and cellular biology 15 (5), 2612-2624, 1995 | 1607 | 1995 |
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas M Loda, B Cukor, SW Tam, P Lavin, M Fiorentinc, GF Draetta, JM Jessup, ... Nature medicine 3 (2), 231-234, 1997 | 1405 | 1997 |
The SCF ubiquitin ligase: insights into a molecular machine T Cardozo, M Pagano Nature reviews Molecular cell biology 5 (9), 739-751, 2004 | 1338 | 2004 |
Deregulated proteolysis by the F-box proteins SKP2 and β-TrCP: tipping the scales of cancer D Frescas, M Pagano Nature Reviews Cancer 8 (6), 438-449, 2008 | 1057 | 2008 |
Regulation of the cdk inhibitor p27 and its deregulation in cancer J Slingerland, M Pagano Journal of cellular physiology 183 (1), 10-17, 2000 | 957 | 2000 |
The F-box protein family ET Kipreos, M Pagano Genome biology 1, 1-7, 2000 | 936 | 2000 |
S6K1-and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth NV Dorrello, A Peschiaroli, D Guardavaccaro, NH Colburn, NE Sherman, ... Science 314 (5798), 467-471, 2006 | 932 | 2006 |
Systematic analysis and nomenclature of mammalian F-box proteins J Jin, T Cardozo, RC Lovering, SJ Elledge, M Pagano, JW Harper Genes & development 18 (21), 2573-2580, 2004 | 803 | 2004 |
Insights into SCF ubiquitin ligases from the structure of the Skp1–Skp2 complex BA Schulman, AC Carrano, PD Jeffrey, Z Bowen, ERE Kinnucan, ... Nature 408 (6810), 381-386, 2000 | 769 | 2000 |
Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation A Montagnoli, F Fiore, E Eytan, AC Carrano, GF Draetta, A Hershko, ... Genes & development 13 (9), 1181-1189, 1999 | 752 | 1999 |
Mechanisms and function of substrate recruitment by F-box proteins JR Skaar, JK Pagan, M Pagano Nature reviews Molecular cell biology 14 (6), 369-381, 2013 | 717 | 2013 |
Control of the SCFSkp2–Cks1 ubiquitin ligase by the APC/CCdh1 ubiquitin ligase T Bashir, NV Dorrello, V Amador, D Guardavaccaro, M Pagano Nature 428 (6979), 190-193, 2004 | 617 | 2004 |
The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27 D Ganoth, G Bornstein, TK Ko, B Larsen, M Tyers, M Pagano, A Hershko Nature cell biology 3 (3), 321-324, 2001 | 615 | 2001 |
SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins L Busino, F Bassermann, A Maiolica, C Lee, PM Nolan, SIH Godinho, ... science 316 (5826), 900-904, 2007 | 603 | 2007 |