| CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ... Nature communications 8 (1), 14432, 2017 | 538 | 2017 |
| Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration S Balaban, RF Shearer, LS Lee, M van Geldermalsen, M Schreuder, ... Cancer & metabolism 5, 1-14, 2017 | 387 | 2017 |
| TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes T Gudjonsson, M Altmeyer, V Savic, L Toledo, C Dinant, M Grøfte, ... Cell 150 (4), 697-709, 2012 | 372 | 2012 |
| Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities L Belfiore, DN Saunders, M Ranson, KJ Thurecht, G Storm, KL Vine Journal of controlled release 277, 1-13, 2018 | 270 | 2018 |
| Walking the tightrope: proteostasis and neurodegenerative disease JJ Yerbury, L Ooi, A Dillin, DN Saunders, DM Hatters, PM Beart, ... Journal of neurochemistry 137 (4), 489-505, 2016 | 230 | 2016 |
| Revisiting the biological roles of PAI2 (SERPINB2) in cancer DR Croucher, DN Saunders, S Lobov, M Ranson Nature Reviews Cancer 8 (7), 535-545, 2008 | 213 | 2008 |
| Systematic approaches to identify E3 ligase substrates M Iconomou, DN Saunders Biochemical Journal 473 (22), 4083-4101, 2016 | 199 | 2016 |
| Adipocyte–tumor cell metabolic crosstalk in breast cancer AJ Hoy, S Balaban, DN Saunders Trends in molecular medicine 23 (5), 381-392, 2017 | 152 | 2017 |
| Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions NE Farrawell, IA Lambert-Smith, ST Warraich, IP Blair, DN Saunders, ... Scientific reports 5 (1), 13416, 2015 | 150 | 2015 |
| Functional roles of the E3 ubiquitin ligase UBR5 in cancer RF Shearer, M Iconomou, CKW Watts, DN Saunders Molecular Cancer Research 13 (12), 1523-1532, 2015 | 144 | 2015 |
| Distinct requirement for an intact dimer interface in wild‐type, V600E and kinase‐dead B‐Raf signalling M Röring, R Herr, GJ Fiala, K Heilmann, S Braun, AE Eisenhardt, ... The EMBO journal 31 (11), 2629-2647, 2012 | 139 | 2012 |
| Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta SL Withington, AN Scott, DN Saunders, KL Floro, JI Preis, J Michalicek, ... Developmental biology 294 (1), 67-82, 2006 | 127 | 2006 |
| Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS P Ciryam, IA Lambert-Smith, DM Bean, R Freer, F Cid, GG Tartaglia, ... Proceedings of the National Academy of Sciences 114 (20), E3935-E3943, 2017 | 114 | 2017 |
| Germline mutations in CDH1 are infrequent in women with early-onset or familial lobular breast cancers KA Schrader, S Masciari, N Boyd, C Salamanca, J Senz, DN Saunders, ... Journal of medical genetics 48 (1), 64-68, 2011 | 112 | 2011 |
| Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway DR Croucher, F Hochgräfe, L Zhang, L Liu, RJ Lyons, D Rickwood, ... Cancer research 73 (6), 1969-1980, 2013 | 103 | 2013 |
| Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro LG Horvath, SM Henshall, JG Kench, DN Saunders, CS Lee, D Golovsky, ... Clinical cancer research 10 (2), 615-625, 2004 | 103 | 2004 |
| Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity GE Stillfried, DN Saunders, M Ranson Breast Cancer Research 9, 1-11, 2007 | 102 | 2007 |
| Experimental design for stable genetic manipulation in mammalian cell lines: lentivirus and alternatives R Shearer, S Darren Genes to Cells, 2014 | 94 | 2014 |
| MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer A Cipponi, DL Goode, J Bedo, MJ McCabe, M Pajic, DR Croucher, ... Science 368 (6495), 1127-1131, 2020 | 93 | 2020 |
| SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer NLE Harris, C Vennin, JRW Conway, KL Vine, M Pinese, MJ Cowley, ... Oncogene 36 (30), 4288-4298, 2017 | 91 | 2017 |
Marie RansonSchool of Chemistry and Molecular Bioscience, Molecular Horizons, University of WollongongAdresse e-mail validée de uow.edu.au