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Nahum Sonenberg
Nahum Sonenberg
Gilman Cheney Professor in Biochemistry
Adresse e-mail validée de mcgill.ca - Page d'accueil
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Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
W Filipowicz, SN Bhattacharyya, N Sonenberg
Nature reviews genetics 9 (2), 102-114, 2008
65692008
Upstream and downstream of mTOR
N Hay, N Sonenberg
Genes & development 18 (16), 1926-1945, 2004
55312004
Regulation of translation initiation in eukaryotes: mechanisms and biological targets
N Sonenberg, AG Hinnebusch
Cell 136 (4), 731-745, 2009
38352009
Regulation of mRNA translation and stability by microRNAs
MR Fabian, N Sonenberg, W Filipowicz
Annual review of biochemistry 79 (1), 351-379, 2010
37042010
eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation
AC Gingras, B Raught, N Sonenberg
Annual review of biochemistry 68 (1), 913-963, 1999
27691999
Internal initiation of translation of eukaryotic mRNA directed by a sequence derived from poliovirus RNA
J Pelletier, N Sonenberg
Nature 334 (6180), 320-325, 1988
26401988
Regulation of translation initiation by FRAP/mTOR
AC Gingras, B Raught, N Sonenberg
Genes & development 15 (7), 807-826, 2001
17732001
Translational control in stress and apoptosis
M Holcik, N Sonenberg
Nature reviews Molecular cell biology 6 (4), 318-327, 2005
17152005
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
AC Gingras, SP Gygi, B Raught, RD Polakiewicz, RT Abraham, ...
Genes & development 13 (11), 1422-1437, 1999
16861999
Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function
A Pause, GJ Belsham, AC Gingras, O Donzé, TA Lin, JC Lawrence Jr, ...
Nature 371 (6500), 762-767, 1994
16271994
Metformin is an AMP kinase–dependent growth inhibitor for breast cancer cells
M Zakikhani, R Dowling, IG Fantus, N Sonenberg, M Pollak
Cancer research 66 (21), 10269-10273, 2006
13462006
Regulation of cap-dependent translation by eIF4E inhibitory proteins
JD Richter, N Sonenberg
Nature 433 (7025), 477-480, 2005
12612005
Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5'cap
A Lazaris-Karatzas, KS Montine, N Sonenberg
Nature 345 (6275), 544-547, 1990
12491990
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
AL Shaffer, M Shapiro-Shelef, NN Iwakoshi, AH Lee, SB Qian, H Zhao, ...
Immunity 21 (1), 81-93, 2004
12212004
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
MR Fabian, N Sonenberg
Nature structural & molecular biology 19 (6), 586-593, 2012
12072012
Hierarchical phosphorylation of the translation inhibitor 4E-BP1
AC Gingras, B Raught, SP Gygi, A Niedzwiecka, M Miron, SK Burley, ...
Genes & development 15 (21), 2852-2864, 2001
11602001
Metformin inhibits mammalian target of rapamycin–dependent translation initiation in breast cancer cells
RJO Dowling, M Zakikhani, IG Fantus, M Pollak, N Sonenberg
Cancer research 67 (22), 10804-10812, 2007
11482007
4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt (PKB) signaling pathway
AC Gingras, SG Kennedy, MA O’Leary, N Sonenberg, N Hay
Genes & development 12 (4), 502-513, 1998
11451998
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
DF Stojdl, B Lichty, S Knowles, R Marius, H Atkins, N Sonenberg, JC Bell
Nature medicine 6 (7), 821-825, 2000
10852000
Translational control by 5′-untranslated regions of eukaryotic mRNAs
AG Hinnebusch, IP Ivanov, N Sonenberg
Science 352 (6292), 1413-1416, 2016
10732016
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