β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection T Noma, A Lemaire, SVN Prasad, L Barki-Harrington, DG Tilley, J Chen, ... The Journal of clinical investigation 117 (9), 2445-2458, 2007 | 542 | 2007 |
Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system DH Maurice, D Palmer, DG Tilley, HA Dunkerley, SJ Netherton, ... Molecular pharmacology 64 (3), 533-546, 2003 | 424 | 2003 |
β-Blockers alprenolol and carvedilol stimulate β-arrestin-mediated EGFR transactivation IM Kim, DG Tilley, J Chen, NC Salazar, EJ Whalen, JD Violin, ... Proceedings of the National Academy of Sciences 105 (38), 14555-14560, 2008 | 330 | 2008 |
Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway Y Yin, X Li, X Sha, H Xi, YF Li, Y Shao, J Mai, A Virtue, J Lopez-Pastrana, ... Arteriosclerosis, thrombosis, and vascular biology 35 (4), 804-816, 2015 | 212 | 2015 |
G protein–dependent and G protein–independent signaling pathways and their impact on cardiac function DG Tilley Circulation research 109 (2), 217-230, 2011 | 191 | 2011 |
β-arrestin–biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction R Carr III, J Schilling, J Song, RL Carter, Y Du, SM Yoo, CJ Traynham, ... Proceedings of the National Academy of Sciences 113 (28), E4107-E4116, 2016 | 134 | 2016 |
β-Arrestin mediates β1-adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling DG Tilley, IM Kim, PA Patel, JD Violin, HA Rockman Journal of Biological Chemistry 284 (30), 20375-20386, 2009 | 123 | 2009 |
BAG3: a new player in the heart failure paradigm T Knezevic, VD Myers, J Gordon, DG Tilley, TE Sharp, JF Wang, K Khalili, ... Heart failure reviews 20, 423-434, 2015 | 115 | 2015 |
Role of β-adrenergic receptor signaling and desensitization in heart failure: new concepts and prospects for treatment DG Tilley, HA Rockman Expert review of cardiovascular therapy 4 (3), 417-432, 2006 | 109 | 2006 |
Expression of phosphodiesterase 4D (PDE4D) is regulated by both the cyclic AMP-dependent protein kinase and mitogen-activated protein kinase signaling pathways: a potential … H Liu, D Palmer, SL Jimmo, DG Tilley, HA Dunkerley, SC Pang, ... Journal of Biological Chemistry 275 (34), 26615-26624, 2000 | 108 | 2000 |
Role of epidermal growth factor receptor and endoplasmic reticulum stress in vascular remodeling induced by angiotensin II T Takayanagi, T Kawai, SJ Forrester, T Obama, T Tsuji, Y Fukuda, ... Hypertension 65 (6), 1349-1355, 2015 | 106 | 2015 |
Decreased levels of BAG3 in a family with a rare variant and in idiopathic dilated cardiomyopathy AM Feldman, RL Begay, T Knezevic, VD Myers, DB Slavov, W Zhu, ... Journal of cellular physiology 229 (11), 1697-1702, 2014 | 97 | 2014 |
GRK5-mediated exacerbation of pathological cardiac hypertrophy involves facilitation of nuclear NFAT activity JE Hullmann, LA Grisanti, CA Makarewich, E Gao, JI Gold, JK Chuprun, ... Circulation research 115 (12), 976-985, 2014 | 94 | 2014 |
The role of leukocytes in diabetic cardiomyopathy A Bajpai, DG Tilley Frontiers in physiology 9, 1547, 2018 | 85 | 2018 |
Interleukin-10 inhibits bone marrow fibroblast progenitor cell–mediated cardiac fibrosis in pressure-overloaded myocardium SK Verma, VNS Garikipati, P Krishnamurthy, SM Schumacher, LA Grisanti, ... Circulation 136 (10), 940-953, 2017 | 84 | 2017 |
Nuclear translocation of cardiac G protein-Coupled Receptor kinase 5 downstream of select Gq-activating hypertrophic ligands is a calmodulin-dependent process JI Gold, JS Martini, J Hullmann, E Gao, JK Chuprun, L Lee, DG Tilley, ... PloS one 8 (3), e57324, 2013 | 80 | 2013 |
BAG3 regulates contractility and Ca2+ homeostasis in adult mouse ventricular myocytes AM Feldman, J Gordon, JF Wang, J Song, XQ Zhang, VD Myers, DG Tilley, ... Journal of molecular and cellular cardiology 92, 10-20, 2016 | 79 | 2016 |
Leukocyte-Expressed β2-Adrenergic Receptors Are Essential for Survival After Acute Myocardial Injury LA Grisanti, AM Gumpert, CJ Traynham, JE Gorsky, AA Repas, E Gao, ... Circulation 134 (2), 153-167, 2016 | 77 | 2016 |
Adeno-associated virus serotype 9–driven expression of BAG3 improves left ventricular function in murine hearts with left ventricular dysfunction secondary to a myocardial … T Knezevic, VD Myers, F Su, JF Wang, J Song, XQ Zhang, E Gao, G Gao, ... JACC: Basic to Translational Science 1 (7), 647-656, 2016 | 75 | 2016 |
Vascular smooth muscle cell phosphodiesterase (PDE) 3 and PDE4 activities and levels are regulated by cyclic AMP in vivo DG Tilley, DH Maurice Molecular pharmacology 62 (3), 497-506, 2002 | 74 | 2002 |