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Hy Levitsky
Hy Levitsky
Professor of Oncology, Medicine, Urology
Adresse e-mail validée de jhmi.edu
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Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor …
G Dranoff, E Jaffee, A Lazenby, P Golumbek, H Levitsky, K Brose, ...
Proceedings of the National Academy of Sciences 90 (8), 3539-3543, 1993
34321993
The Central Role of CD4+ T Cells in the Antitumor Immune Response
K Hung, R Hayashi, A Lafond-Walker, C Lowenstein, D Pardoll, ...
The Journal of experimental medicine 188 (12), 2357-2368, 1998
17211998
Role of LAG-3 in regulatory T cells
CT Huang, CJ Workman, D Flies, X Pan, AL Marson, G Zhou, EL Hipkiss, ...
Immunity 21 (4), 503-513, 2004
16472004
Role of bone marrow-derived cells in presenting MHC class I-restricted tumor antigens
AYC Huang, P Golumbek, M Ahmadzadeh, E Jaffee, D Pardoll, H Levitsky
Science 264 (5161), 961-965, 1994
15291994
Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy
CH Ries, MA Cannarile, S Hoves, J Benz, K Wartha, V Runza, ...
Cancer cell 25 (6), 846-859, 2014
13782014
Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response
ER Fearon, DM Pardoll, T Itaya, P Golumbek, HI Levitsky, JW Simons, ...
Cell 60 (3), 397-403, 1990
12631990
Treatment of established tumors with a novel vaccine that enhances major histocompatibility class II presentation of tumor antigen
KY Lin, FG Guarnieri, KF Staveley-O'Carroll, HI Levitsky, JT August, ...
Cancer research 56 (1), 21-26, 1996
12181996
Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4
PT Golumbek, AJ Lazenby, HI Levitsky, LM Jaffee, H Karasuyama, ...
Science 254 (5032), 713-716, 1991
9511991
Induction of antigen-specific T cell anergy: an early event in the course of tumor progression
K Staveley-O’Carroll, E Sotomayor, J Montgomery, I Borrello, L Hwang, ...
Proceedings of the National Academy of Sciences 95 (3), 1178-1183, 1998
9211998
Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte …
JW Simons, B Mikhak, JF Chang, AM DeMarzo, MA Carducci, M Lim, ...
Cancer research 59 (20), 5160-5168, 1999
5651999
Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by ex Vivo Granulocyte-Macrophage Colony-stimulating Factor Gene Transfer
JW Simons, EM Jaffee, CE Weber, HI Levitsky, WG Nelson, MA Carducci, ...
Cancer research 57 (8), 1537-1546, 1997
5411997
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40
EM Sotomayor, I Borrello, E Tubb, FM Rattis, H Bien, Z Lu, S Fein, ...
Nature medicine 5 (7), 780-787, 1999
5241999
High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease
L Luznik, J Bolaños-Meade, M Zahurak, AR Chen, BD Smith, R Brodsky, ...
Blood, The Journal of the American Society of Hematology 115 (16), 3224-3230, 2010
4782010
Depleting tumor-specific Tregs at a single site eradicates disseminated tumors
A Marabelle, H Kohrt, I Sagiv-Barfi, B Ajami, RC Axtell, G Zhou, ...
The Journal of clinical investigation 123 (6), 2447-2463, 2013
4692013
Engineering an intracellular pathway for major histocompatibility complex class II presentation of antigens.
TC Wu, FG Guarnieri, KF Staveley-O'Carroll, RP Viscidi, HI Levitsky, ...
Proceedings of the National Academy of Sciences 92 (25), 11671-11675, 1995
4481995
Amplification of tumor-specific regulatory T cells following therapeutic cancer vaccines
G Zhou, CG Drake, HI Levitsky
Blood 107 (2), 628-636, 2006
3442006
Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunity
DJ Morgan, HTC Kreuwel, S Fleck, HI Levitsky, DM Pardoll, LA Sherman
The Journal of Immunology 160 (2), 643-651, 1998
3101998
In vivo cross-priming of MHC class I–restricted antigens requires the TAP transporter
AYC Huang, AT Bruce, DM Pardoll, HI Levitsky
Immunity 4 (4), 349-355, 1996
3011996
Cell polarity: an examination of its behavioral expression and its consequences for polymorphonuclear leukocyte chemotaxis.
SH Zigmond, HI Levitsky, BJ Kreel
The Journal of cell biology 89 (3), 585-592, 1981
2981981
Natural regulatory T cells and de novo-induced regulatory T cells contribute independently to tumor-specific tolerance
G Zhou, HI Levitsky
The Journal of Immunology 178 (4), 2155-2162, 2007
2682007
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