The IL-12 family of cytokines in infection, inflammation and autoimmune disorders K Gee, C Guzzo, NF Che Mat, W Ma, A Kumar Inflammation & Allergy-Drug Targets (Formerly Current Drug Targets …, 2009 | 502 | 2009 |
Interleukin-27 induces a STAT1/3-and NF-κB-dependent proinflammatory cytokine profile in human monocytes C Guzzo, NFC Mat, K Gee Journal of Biological Chemistry 285 (32), 24404-24411, 2010 | 132 | 2010 |
IL-27 enhances LPS-induced proinflammatory cytokine production via upregulation of TLR4 expression and signaling in human monocytes C Guzzo, A Ayer, S Basta, BW Banfield, K Gee The Journal of Immunology 188 (2), 864-873, 2012 | 127 | 2012 |
Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for Toll-like receptor activation and cellular signaling S Abdulkhalek, SR Amith, SL Franchuk, P Jayanth, M Guo, T Finlay, ... Journal of Biological Chemistry 286 (42), 36532-36549, 2011 | 115 | 2011 |
Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer Q Liu, P Acharya, MA Dolan, P Zhang, C Guzzo, J Lu, A Kwon, D Gururani, ... Nature structural & molecular biology 24 (4), 370-378, 2017 | 109 | 2017 |
The incorporation of host proteins into the external HIV-1 envelope J Burnie, C Guzzo Viruses 11 (1), 85, 2019 | 67 | 2019 |
Virion incorporation of integrin α4β7 facilitates HIV-1 infection and intestinal homing C Guzzo, D Ichikawa, C Park, D Phillips, Q Liu, P Zhang, A Kwon, H Miao, ... Science immunology 2 (11), eaam7341, 2017 | 67 | 2017 |
Interdomain stabilization impairs CD4 binding and improves immunogenicity of the HIV-1 envelope trimer P Zhang, J Gorman, H Geng, Q Liu, Y Lin, Y Tsybovsky, EP Go, B Dey, ... Cell Host & Microbe 23 (6), 832-844. e6, 2018 | 50 | 2018 |
IL-27 enhances LPS-induced IL-1β in human monocytes and murine macrophages C Petes, C Wynick, C Guzzo, D Mehta, S Logan, BW Banfield, S Basta, ... Journal of leukocyte biology 102 (1), 83-94, 2017 | 43 | 2017 |
Tyrosine sulfation in the second variable loop (V2) of HIV-1 gp120 stabilizes V2–V3 interaction and modulates neutralization sensitivity R Cimbro, TR Gallant, MA Dolan, C Guzzo, P Zhang, Y Lin, H Miao, ... Proceedings of the National Academy of Sciences 111 (8), 3152-3157, 2014 | 43 | 2014 |
The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1 C Guzzo, J Fox, Y Lin, H Miao, R Cimbro, BF Volkman, AS Fauci, P Lusso PLoS pathogens 9 (12), e1003852, 2013 | 43 | 2013 |
Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo TM Finlay, S Abdulkhalek, A Gilmour, C Guzzo, P Jayanth, SR Amith, ... Glycoconjugate journal 27, 583-600, 2010 | 43 | 2010 |
IL-27 increases BST-2 expression in human monocytes and T cells independently of type I IFN C Guzzo, M Jung, A Graveline, BW Banfield, K Gee Scientific reports 2 (1), 974, 2012 | 41 | 2012 |
Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Gα i … TM Finlay, P Jayanth, SR Amith, A Gilmour, C Guzzo, K Gee, R Beyaert, ... Glycoconjugate journal 27, 329-348, 2010 | 40 | 2010 |
Impact of HIV infection, highly active antiretroviral therapy, and hepatitis C coinfection on serum interleukin-27 C Guzzo, WM Hopman, NFC Mat, W Wobeser, K Gee Aids 24 (9), 1371-1374, 2010 | 34 | 2010 |
The TLR2 agonists lipoteichoic acid and Pam3CSK4 induce greater pro-inflammatory responses than inactivated Mycobacterium butyricum V Gambhir, C Yildiz, R Mulder, S Siddiqui, C Guzzo, M Szewczuk, K Gee, ... Cellular immunology 280 (1), 101-107, 2012 | 33 | 2012 |
Engineering metamorphic chemokine lymphotactin/XCL1 into the GAG-binding, HIV-inhibitory dimer conformation JC Fox, RC Tyler, C Guzzo, RL Tuinstra, FC Peterson, P Lusso, ... ACS chemical biology 10 (11), 2580-2588, 2015 | 30 | 2015 |
Interleukin-23-induced interleukin-23 receptor subunit expression is mediated by the Janus kinase/signal transducer and activation of transcription pathway in human CD4 T cells NF Che Mat, X Zhang, C Guzzo, K Gee Journal of Interferon & Cytokine Research 31 (4), 363-371, 2011 | 28 | 2011 |
IL-27-induced gene expression is downregulated in HIV-infected subjects C Guzzo, WM Hopman, NF Che Mat, W Wobeser, K Gee Public Library of Science 7 (9), e45706, 2012 | 21 | 2012 |
Structural determinants for the selective anti-HIV-1 activity of the all-β alternative conformer of XCL1 C Guzzo, JC Fox, H Miao, BF Volkman, P Lusso Journal of virology 89 (17), 9061-9067, 2015 | 20 | 2015 |