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Santosh Chauhan
Santosh Chauhan
Senior Principal Scientist; Wellcome-DBT & EMBO GIN Fellow; CSIR-CCMB & Institute of Life Sciences
Adresse e-mail validée de ccmb.res.in - Page d'accueil
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
13667*2016
Secretory autophagy
M Ponpuak, MA Mandell, T Kimura, S Chauhan, C Cleyrat, V Deretic
Current opinion in cell biology 35, 106-116, 2015
5072015
TRIMs and galectins globally cooperate and TRIM16 and galectin-3 co-direct autophagy in endomembrane damage homeostasis
S Chauhan, S Kumar, A Jain, M Ponpuak, MH Mudd, T Kimura, SW Choi, ...
Developmental cell 39 (1), 13-27, 2016
4262016
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition
MA Mandell, A Jain, J Arko-Mensah, S Chauhan, T Kimura, C Dinkins, ...
Developmental cell 30 (4), 394-409, 2014
3452014
ZKSCAN3 is a master transcriptional repressor of autophagy
S Chauhan, JG Goodwin, S Chauhan, G Manyam, J Wang, AM Kamat, ...
Molecular cell 50 (1), 16-28, 2013
2912013
Neutral lipid stores and lipase PNPLA5 contribute to autophagosome biogenesis
N Dupont, S Chauhan, J Arko-Mensah, EF Castillo, A Masedunskas, ...
Current Biology 24 (6), 609-620, 2014
2532014
IRGM governs the core autophagy machinery to conduct antimicrobial defense
S Chauhan, MA Mandell, V Deretic
Molecular cell 58 (3), 507-521, 2015
2512015
The Crohn’s disease risk factor IRGM limits NLRP3 inflammasome activation by impeding its assembly and by mediating its selective autophagy
S Mehto, KK Jena, P Nath, S Chauhan, SP Kolapalli, SK Das, PK Sahoo, ...
Molecular cell 73 (3), 429-445. e7, 2019
1842019
Immunologic manifestations of autophagy
V Deretic, T Kimura, G Timmins, P Moseley, S Chauhan, M Mandell
The Journal of clinical investigation 125 (1), 75-84, 2015
1612015
Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential
S Chauhan, Z Ahmed, SB Bradfute, J Arko-Mensah, MA Mandell, ...
Nature communications 6 (1), 8620, 2015
1552015
Autophagy as an immune effector against tuberculosis
SB Bradfute, EF Castillo, J Arko-Mensah, S Chauhan, S Jiang, M Mandell, ...
Current opinion in microbiology 16 (3), 355-365, 2013
1302013
TRIM16 controls assembly and degradation of protein aggregates by modulating the p62‐NRF2 axis and autophagy
KK Jena, SP Kolapalli, S Mehto, P Nath, B Das, PK Sahoo, A Ahad, ...
The EMBO journal 37 (18), e98358, 2018
1142018
Cooperative binding of phosphorylated DevR to upstream sites is necessary and sufficient for activation of the Rv3134c-devRS operon in Mycobacterium tuberculosis: implication …
S Chauhan, JS Tyagi
Journal of bacteriology 190 (12), 4301-4312, 2008
932008
Transcription and autoregulation of the Rv3134c-devR-devS operon of Mycobacterium tuberculosis
G Bagchi, S Chauhan, D Sharma, JS Tyagi
Microbiology 151 (12), 4045-4053, 2005
872005
Comprehensive insights into Mycobacterium tuberculosis DevR (DosR) regulon activation switch
S Chauhan, D Sharma, A Singh, A Surolia, JS Tyagi
Nucleic acids research 39 (17), 7400-7414, 2011
762011
Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response
KK Jena, S Mehto, P Nath, NR Chauhan, R Sahu, K Dhar, SK Das, ...
EMBO reports 21 (9), e50051, 2020
572020
Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy
S Chauhan, MA Mandell, V Deretic
Autophagy 12 (2), 429-431, 2016
522016
Galectins and TRIMs directly interact and orchestrate autophagic response to endomembrane damage
S Kumar, S Chauhan, A Jain, M Ponpuak, SW Choi, M Mudd, R Peters, ...
Autophagy 13 (6), 1086-1087, 2017
512017
CmtR, a cadmium‐sensing ArsR–SmtB repressor, cooperatively interacts with multiple operator sites to autorepress its transcription in Mycobacterium tuberculosis
S Chauhan, A Kumar, A Singhal, JS Tyagi, H Krishna Prasad
The FEBS journal 276 (13), 3428-3439, 2009
452009
IRGM restrains NLRP3 inflammasome activation by mediating its SQSTM1/p62-dependent selective autophagy
S Mehto, S Chauhan, KK Jena, NR Chauhan, P Nath, R Sahu, K Dhar, ...
Autophagy 15 (9), 1645-1647, 2019
432019
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